Issue 0, 1967

Quinazolines and 1,4-benzodiazepines. Part XXXII. The acetic anhydride rearrangement of 1,4-benzodiazepinones to isoindoles

Abstract

1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-ones unsubstituted in the 1-position rearrange to 1-acetyliso-indoles in the presence of acetic anhydride and pyridine. The structure of the rearranged products has been established by alternative syntheses, and the mechanism of the rearrangement is discussed.

Article information

Article type
Paper

J. Chem. Soc. C, 1967, 366-367

Quinazolines and 1,4-benzodiazepines. Part XXXII. The acetic anhydride rearrangement of 1,4-benzodiazepinones to isoindoles

R. I. Fryer, B. Brust, J. V. Earley and L. H. Sternbach, J. Chem. Soc. C, 1967, 366 DOI: 10.1039/J39670000366

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