Asymmetric synthesis. Part III. The reduction of ketones with the ethanol modified lithium aluminium hydride-3-O-benzyl-1,2-O-cyclohexylidene-α-D-glucofuranose complex
Abstract
The asymmetric reduction of ketones with the ethanol modified lithium aluminium hydride–sugar complex yields optically active alcohols of up to 70% optical purity having the R-configuration.