The reaction of phenylacetonitrile with carbon disulphide and the preparation of 4-aryl isothiazoles
Abstract
Dithioacid salts have been prepared in good yield from phenylacetonitrile and related compounds by reaction with carbon disulphide in benzene solution using sodium hydride as the base; substituted isothiazoles are formed on heating these salts, in ethanol solution, with sulphur.