Carcinogenic nitrogen compounds. Part LIII. Thiazole isosteres of dibenzacridines and dibenzocarbazoles
Abstract
Bz-Amino-derivatives of benzothiazole readily underwent Ullmann–Fetvadjian condensation with naphthols and paraformaldehyde, to give thiazole isosteres of carcinogenic dibenzacridines; with 4-hydroxycoumarin, coumarinothiazoloquinolines were obtained. Bz-Hydrazinobenzothiazoles were successfully used for the preparation of thiazole isosteres of carcinogenic dibenzocarbazoles.