Issue 0, 1966

The chemotherapy of schistosomiasis. Part VII. 2-Methyl- and 2-(substituted methyl)-4-aminophenyl ethers

Abstract

Chloromethylation of p-nitrophenol or its alkyl ethers gave reactive 2-chloromethyl intermediates which have been converted into 2-hydroxymethyl-(VII), 2-mercaptomethyl-(II), or 2-aminomethyl-4-nitrophenyl ethers (X), and various acyl, alkyl, aryl, and sulphone derivatives. The amines (VIII) obtained on reduction have been studied as schistosomicides.

Article information

Article type
Paper

J. Chem. Soc. C, 1966, 873-880

The chemotherapy of schistosomiasis. Part VII. 2-Methyl- and 2-(substituted methyl)-4-aminophenyl ethers

R. F. Collins and M. Davis, J. Chem. Soc. C, 1966, 873 DOI: 10.1039/J39660000873

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements