The unambiguous synthesis of 2-amino-7,8-dihydro-4-hydroxypteridine (III; R = H) is described. Reaction of this dihydropteridine with various nucleophiles has been studied, and the possible biochemical significance of the results is discussed.
A. Stuart, H. C. S. Wood and D. Duncan, J. Chem. Soc. C, 1966, 285 DOI: 10.1039/J39660000285
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