The formation, ionisation, and spectra of some alkylamino-pteridines,-purines, and -pyrimidines

Abstract

Under preparative conditions, 2-chloropteridine is shown to react with t-butylamine about 20,000 times faster than does 2-chloropyrimidine, but 2-chloro-6,9-dimethylpurine is butylaminated a little more slowly than is the corresponding 2-chloro-4,6-dimethylpyrimidine. The formation of twelve new alkylaminopteridines and purines are recorded; their ionisation constatns and ultraviolet spectra are compared with those of twanty analogous pyrimidines. Syntheses of three 2-carboxypyrimidines are recorded.