Recent advances in the application of deep eutectic solvents as sustainable media as well as catalysts in organic reactions

Peng Liu, Jian-Wu Hao, Li-Ping Mo and Zhan-Hui Zhang

RSC Adv., 2015, 5, 48675
DOI: 10.1039/C5RA05746A

Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature

Alireza Hasaninejad and Maryam Beyrati

RSC Adv., 2018, 8, 1934
DOI: 10.1039/C7RA13133J

An extremely efficient and green method for the acylation of secondary alcohols, phenols and naphthols with a deep eutectic solvent as the catalyst

Hai Truong Nguyen and Phuong Hoang Tran

RSC Adv., 2016, 6, 98365
DOI: 10.1039/C6RA22757K

Green synthesis and antitumor activity of (E)-diethyl 2-styrylquinoline-3,4-dicarboxylates

Hong Zhang, Jianyuan Wang, Cheng Li, Di Zhao, Tianyu Liang and Yang Li

RSC Adv., 2024, 14, 26820
DOI: 10.1039/D4RA04588B

The deep eutectic melt of sorbitol and metformin hydrochloride: synthesis of 3-substituted 2-aminonaphtho[2,3-b]furan-4,9-diones and their photophysical properties

Kurosh Rad-Moghadam, Seyyed Ali Reza Mousazadeh Hassani and Saeedeh Toorchi Roudsari

RSC Adv., 2016, 6, 13152
DOI: 10.1039/C5RA19619A

Synthesis and characterization of phenol–furfural resins using lignin modified by a low transition temperature mixture

Jun Liu, Ju Wang, Yan Fu and Jie Chang

RSC Adv., 2016, 6, 94588
DOI: 10.1039/C6RA17877D

One-pot three-component synthesis of 1,2,3-triazoles using magnetic NiFe2O4–glutamate–Cu as an efficient heterogeneous catalyst in water

Jun Lu, Er-Qian Ma, Yu-Heng Liu, Ya-Meng Li, Li-Ping Mo and Zhan-Hui Zhang

RSC Adv., 2015, 5, 59167
DOI: 10.1039/C5RA09517D

Determination of phenolic acids in Prunella vulgaris L.: a safe and green extraction method using alcohol-based deep eutectic solvents

Bohou Xia, Dong Yan, Yubing Bai, Jiachi Xie, Yi Cao, Duanfang Liao and Limei Lin

Anal. Methods, 2015, 7, 9354
DOI: 10.1039/C5AY02035B

Preparation of catalytic deep eutectic solvent-based silica microreactors using a non-aqueous sol–gel route

Charlie Batarseh, Anat Levi-Zada and Raed Abu-Reziq

J. Mater. Chem. A, 2019, 7, 2242
DOI: 10.1039/C8TA09021A

Improved stability of salvianolic acid B from Radix Salviae miltiorrhizae in deep eutectic solvents

Jue Chen, Shi-fei Li, Zhi-feng Yao, Da-wei Yang and Li-wei Zhang

Anal. Methods, 2016, 8, 2502
DOI: 10.1039/C5AY03351A

Meglumine catalyzed one-pot, three-component combinatorial synthesis of pyrazoles bearing a coumarin unit

Xiao-Tang Li, Yu-Heng Liu, Xin Liu and Zhan-Hui Zhang

RSC Adv., 2015, 5, 25625
DOI: 10.1039/C5RA01677K

A green and efficient method for the synthesis of pyrroles using a deep eutectic solvent ([CholineCl][ZnCl2]3) under solvent-free sonication

Hai Truong Nguyen, Duy-Khiem Nguyen Chau and Phuong Hoang Tran

New J. Chem., 2017, 41, 12481
DOI: 10.1039/C7NJ02396K

An efficient and green method for regio- and chemo-selective Friedel–Crafts acylations using a deep eutectic solvent ([CholineCl][ZnCl2]3)

Phuong Hoang Tran, Hai Truong Nguyen, Poul Erik Hansen and Thach Ngoc Le

RSC Adv., 2016, 6, 37031
DOI: 10.1039/C6RA03551E

Direct conversion of shrimp shells to O-acylated chitin with antibacterial and anti-tumor effects by natural deep eutectic solvents

Mi Feng, Xingmei Lu, Jie Zhang, Yi Li, Chunyan Shi, Lingling Lu and Suojiang Zhang

Green Chem., 2019, 21, 87
DOI: 10.1039/C8GC02506A

Morita–Baylis–Hillman reaction in eutectic solvent under aqueous medium

Sanhu Zhao, Hangyu Zhi, Mi Zhang, Qin Yan, Jianfeng Fan and Jinchang Guo

RSC Adv., 2016, 6, 62778
DOI: 10.1039/C6RA04710F

Magnetically separable graphene oxide anchored sulfonic acid: a novel, highly efficient and recyclable catalyst for one-pot synthesis of 3,6-di(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-5-carbonitriles in deep eutectic solvent under microwave irradiation

Mo Zhang, Peng Liu, Yu-Heng Liu, Ze-Ren Shang, Hai-Chuan Hu and Zhan-Hui Zhang

RSC Adv., 2016, 6, 106160
DOI: 10.1039/C6RA19579B

A magnetic metal–organic framework as a highly active heterogeneous catalyst for one-pot synthesis of 2-substituted alkyl and aryl(indolyl)kojic acid derivatives

Hong-Yan Zhang, Xiao-Peng Hao, Li-Ping Mo, Sha-Sha Liu, Wen-Bo Zhang and Zhan-Hui Zhang

New J. Chem., 2017, 41, 7108
DOI: 10.1039/C7NJ01592E

Insight into Speciation and Electrochemistry of Uranyl Ions in Deep Eutectic Solvents

Ruma Gupta, BalGovind Vats, Ashok K. Pandey, Manoj K. Sharma, Pooja Sahu, A. K. Yadav, Sk. Musharaf Ali and Shanmugaperumal Kannan

J. Phys. Chem. B, 2020, 124, 181
DOI: 10.1021/acs.jpcb.9b08197

Molecular Guide for Selecting Green Deep Eutectic Solvents with High Monosaccharide Solubility for Food Applications

Jawaher AlYammahi, Ahmad S. Darwish, Tarek Lemaoui, Abir Boublia, Yacine Benguerba, Inas M. AlNashef and Fawzi Banat

ACS Omega, 2023, 8, 26533
DOI: 10.1021/acsomega.3c03326

An Expeditious and Greener Synthesis of 2-Aminoimidazoles in Deep Eutectic Solvents

Martina Capua, Serena Perrone, Filippo Perna, Paola Vitale, Luigino Troisi, Antonio Salomone and Vito Capriati

Molecules, 2016, 21, 924
DOI: 10.3390/molecules21070924

Novel deep eutectic solvent catalysed Single-Pot open flask synthesis of Tetrasubstituted-1H-Pyrroles

S. Lokesh Kumar, Sumaiya Tabassum and Santhosh Govindaraju

Journal of Molecular Liquids, 2024, 401, 124592
DOI: 10.1016/j.molliq.2024.124592

Recent Progress for the Synthesis of Pyrrole Derivatives – An Update

Dharti Patel, Drashti Shah, Krishi Patel, Ayush Patel, Tushar Bambharoliya, Anjali Mahavar and Ashish Patel

MROC, 2024, 21, 717
DOI: 10.2174/1570193X20666230530161009

A green chemical approach: a straightforward one-pot synthesis of 2-aminothiophene derivatives via Gewald reaction in deep eutectic solvents

Ahmad Shaabani, Seyyed Emad Hooshmand and Hadi Afaridoun

Monatsh Chem, 2017, 148, 711
DOI: 10.1007/s00706-016-1787-6

Can isopiestic method predict the formation of deep eutectic solvents?

Karzan A. Omar and Rahmat Sadeghi

Journal of Molecular Liquids, 2021, 333, 115865
DOI: 10.1016/j.molliq.2021.115865

Database of deep eutectic solvents and their physical properties: A review

Karzan A. Omar and Rahmat Sadeghi

Journal of Molecular Liquids, 2023, 384, 121899
DOI: 10.1016/j.molliq.2023.121899

Deep eutectic solvent (DES) as dual solvent/catalyst for synthesis of α-diazocarbonyl compounds using aldol-type coupling

Maryam Kazemi Miraki, Jamshid Azarnia Mehraban, Elahe Yazdani and Akbar Heydari

Journal of Molecular Liquids, 2017, 234, 129
DOI: 10.1016/j.molliq.2017.03.065

Ternary Choline Chloride-Based Deep Eutectic Solvents: A Review

Abdulalim Ibrahim, Marc Mulamba Tshibangu, Christophe Coquelet and Fabienne Espitalier

ChemEngineering, 2025, 9, 84
DOI: 10.3390/chemengineering9040084

Investigating the Variation in Solvation Interactions of Choline Chloride-Based Deep Eutectic Solvents Formed Using Different Hydrogen Bond Donors

Nabeel Mujtaba Abbasi, Muhammad Qamar Farooq and Jared L. Anderson

ACS Sustainable Chem. Eng., 2021, 9, 11970
DOI: 10.1021/acssuschemeng.1c04375

Preparation of eco-friendly adsorbent for enhancing CO2 adsorption capacity

Farihahusnah Hussin, Mohamed Kheireddine Aroua, Rozita Yusoff and Małgorzata Szlachta

Separation Science and Technology, 2022, 57, 1543
DOI: 10.1080/01496395.2021.1998122

Enhanced CO2 capture performance using deep eutectic solvent-immobilized silica slurry

Sahar Foorginezhad and Xiaoyan Ji

Results in Engineering, 2025, 26, 105162
DOI: 10.1016/j.rineng.2025.105162

One-Pot Multicomponent Reactions in Deep Eutectic Solvents

Aslıhan Ayvaz, Sinem Gorkem Demirbaş, Ahmet Demirbaş and Neslihan Demirbaş

COC, 2023, 27, 585
DOI: 10.2174/1385272827666230427101210

Choline chloride and itaconic acid-based deep eutectic solvent as an efficient and reusable medium for the preparation of 13-aryl-5H-dibenzo[b,i]xanthene-5,7,12,14(13H)-tetraones

Peng Liu, Jian-Wu Hao, Shao-Juan Liang, Guang-Li Liang, Jin-Yu Wang and Zhan-Hui Zhang

Monatsh Chem, 2016, 147, 801
DOI: 10.1007/s00706-015-1571-z

Low melting oxalic acid dihydrate: proline mixture as dual solvent/catalyst for synthesis of spiro[indoline-3,9′-xanthene]trione and dibarbiturate derivatives

D.R. Chandam, A.A. Patravale, S.D. Jadhav and M.B. Deshmukh

Journal of Molecular Liquids, 2017, 240, 98
DOI: 10.1016/j.molliq.2017.05.070

A facile and efficient synthesis of highly functionalized pyrroles via a four-component one-pot reaction in the presence of Ni(II) Schiff base/SBA-15 heterogeneous catalyst

Ghasem Rezanejade Bardajee, Hossein Mahmoodian, Seyed Ata Boraghi, Fatemeh Aghazadeh and Zahir Rezanejad

Res Chem Intermed, 2023, 49, 1959
DOI: 10.1007/s11164-023-04953-4

A practical multigram-scale method for the green synthesis of 5-substituted-1H-tetrazoles in deep eutectic solvent

Xingquan Xiong, Chao Yi, Xu Liao and Shilin Lai

Tetrahedron Letters, 2019, 60, 402
DOI: 10.1016/j.tetlet.2018.12.037

Synthesis of novel benzo naphtho naphthyridines from 2,4‐dicloroquinolines

Prabha Kolandaivel, Satheeshkumar Rajendran and Rajendra Prasad Karnam Jayarampillai

Journal of Heterocyclic Chem, 2021, 58, 1809
DOI: 10.1002/jhet.4312

Bulk and interfacial nanostructure and properties in deep eutectic solvents: Current perspectives and future directions

Saffron J. Bryant, Andrew J. Christofferson, Tamar L. Greaves, Christopher F. McConville, Gary Bryant and Aaron Elbourne

Journal of Colloid and Interface Science, 2022, 608, 2430
DOI: 10.1016/j.jcis.2021.10.163

Insight into structural properties and molecular interactions of maline (choline chloride + malonic acid) and 1, 4- butanediol based pseudo-binary mixture: A thermophysical, spectral, and simulation portrayal

Anil Kumar Jangir, Anil Kumar Nain and Ketan Kuperkar

Journal of Molecular Liquids, 2021, 334, 116050
DOI: 10.1016/j.molliq.2021.116050

Choline chloride and lactic acid: A natural deep eutectic solvent for one-pot rapid construction of spiro[indoline-3,4′-pyrazolo[3,4-b]pyridines]

Wei-Hong Zhang, Meng-Nan Chen, Yi Hao, Xin Jiang, Xiao-Lin Zhou and Zhan-Hui Zhang

Journal of Molecular Liquids, 2019, 278, 124
DOI: 10.1016/j.molliq.2019.01.065

Unveiling the Hidden Performance of Whole Cells in the Asymmetric Bioreduction of Aryl‐containing Ketones in Aqueous Deep Eutectic Solvents

Paola Vitale, Vincenzo Mirco Abbinante, Filippo Maria Perna, Antonio Salomone, Cosimo Cardellicchio and Vito Capriati

Adv Synth Catal, 2017, 359, 1049
DOI: 10.1002/adsc.201601064

DESs: Green solvents for transition metal catalyzed organic reactions

Lifen Peng, Zhifang Hu, Qichao Lu, Zilong Tang, Yinchun Jiao and Xinhua Xu

Chinese Chemical Letters, 2019, 30, 2151
DOI: 10.1016/j.cclet.2019.05.063

Deep Eutectic Solvent: An Efficient and Recyclable Catalyst for Synthesis of Thioethers.

Preeti L. Pant and Ganapati S. Shankarling

ChemistrySelect, 2017, 2, 7645
DOI: 10.1002/slct.201701318

Glycerol‐K2CO3 Deep Eutectic Solvent as Environmentally Friendly Media with Basic and Dehumidifier Synergistic Effect for Running of Willgerodt‐Kindler Reaction

Iman Radfar, Sepideh Abbasi, Maryam Kazemi Miraki, Elahe Yazdani, Meghdad Karimi and Akbar Heydari

ChemistrySelect, 2018, 3, 3265
DOI: 10.1002/slct.201702906

Brønsted acid catalyzed synthesis of 2‐aryl‐quinazolinones via cyclization of 2‐aminobenzamide with benzonitriles in PEG

Sowbhagya Lakshmi Matcha, Bharat Kumar Karasala, Sathish Mohan Botsa and Siddaiah Vidavalur

Journal of Heterocyclic Chem, 2021, 58, 1955
DOI: 10.1002/jhet.4321

Copper Schiff base complex immobilized on silica‐coated Fe3O4 nanoparticles: a recoverable and efficient catalyst for synthesis of polysubstituted pyrroles

Seyedeh Aghigh Hamrahian, Jamshid Rakhtshah, Seyedeh Mohadeseh Mousavi Davijani and Sadegh Salehzadeh

Applied Organom Chemis, 2018, 32
DOI: 10.1002/aoc.4501

Revisit to the synthesis of 1,2,3,4-tetrasubstituted pyrrole derivatives in lactic acid media as a green solvent and catalyst

Dilek Akbaslar, E. Sultan Giray and Oztekin Algul

Mol Divers, 2021, 25, 2321
DOI: 10.1007/s11030-020-10122-1

Choline Chloride-based Eutectic Mixtures for Greener Synthesis of Quinoxaline-2,3-diol Derivatives and Terephthalaldehyde bis-(2-Aminophenylimine)

Kioumars Aghapoor, Farshid Mohsenzadeh, Hossein Reza Darabi and Hani Sayahi

Organic Preparations and Procedures International, 2022, 54, 157
DOI: 10.1080/00304948.2021.2010467

A General, Effcient and Green Procedure for Synthesis of Dihydropyrimidine‐5‐carboxamides in Low Melting Betaine Hydrochloride/Urea Mixture

Peng Liu, Jianwu Hao and Zhanhui Zhang

Chin. J. Chem., 2016, 34, 637
DOI: 10.1002/cjoc.201500862

A low-molecular-weight, long-wavelength emissive Coumarin: Green synthesis, spectral properties, fluorescence enhancement and solvatochromism application

Mingxue You, Liai Bai, JiaYing Xu, Yanze Chen and Yihui Bai

Journal of Molecular Structure, 2024, 1312, 138599
DOI: 10.1016/j.molstruc.2024.138599

Nanostructure of a deep eutectic solvent at solid interfaces

Aaron Elbourne, Nastaran Meftahi, Tamar L. Greaves, Christopher F. McConville, Gary Bryant, Saffron J. Bryant and Andrew J. Christofferson

Journal of Colloid and Interface Science, 2021, 591, 38
DOI: 10.1016/j.jcis.2021.01.089

Degradation of Deep-Eutectic Solvents Based on Choline Chloride and Carboxylic Acids

Nerea Rodriguez Rodriguez, Adriaan van den Bruinhorst, Laura J. B. M. Kollau, Maaike C. Kroon and Koen Binnemans

ACS Sustainable Chem. Eng., 2019, 7, 11521
DOI: 10.1021/acssuschemeng.9b01378

Electrified interfaces of deep eutectic solvents

Renata Costa, Ana T.S.C. Brandão, Carlos M. Pereira and A. Fernando Silva

Electrochimica Acta, 2023, 461, 142653
DOI: 10.1016/j.electacta.2023.142653

Multicomponent domino reactions in deep eutectic solvent: An efficient strategy to synthesize multisubstituted cyclohexa-1,3-dienamines

Najmedin Azizi, Tahereh Soleymani Ahooie and Mohammad Mahmoudi Hashemi

Journal of Molecular Liquids, 2017, 246, 221
DOI: 10.1016/j.molliq.2017.09.049

Deep Eutectic Solvent: An Efficient Catalyst for C-O Coupling Reactions.

Preeti L. Pant and Ganapati S. Shankarling

ChemistrySelect, 2017, 2, 4892
DOI: 10.1002/slct.201700584

Sulfamic acid promoted expeditious and column chromatography free synthesis of functionalized spiro [indoline-3, 7′-pyrano [3, 2-c: 5, 6-c'] dichromene]-2, 6′, 8′-trione derivatives under reflux conditions

Kajal Mal and Chhanda Mukhopadhyay

Journal of Molecular Structure, 2022, 1253, 132213
DOI: 10.1016/j.molstruc.2021.132213

Glucose:urea:NH4Cl low melting mixture for the synthesis of symmetric azines

Letcy V. Theresa, M. Shaibuna and K. Sreekumar

Synthetic Communications, 2019, 49, 3148
DOI: 10.1080/00397911.2019.1657151

Efficient and promising oxidative desulfurization of fuel using Fenton like deep eutectic solvent

Fatemeh Armandsefat, Sholeh Hamzehzadeh and Najmedin Azizi

Sci Rep, 2024, 14
DOI: 10.1038/s41598-024-62781-x

Deep eutectic solvent immobilized on SBA-15 as a novel separable catalyst for one-pot three-component Mannich reaction

Najmedin Azizi and Mahtab Edrisi

Microporous and Mesoporous Materials, 2017, 240, 130
DOI: 10.1016/j.micromeso.2016.11.009

Natural Deep Eutectic Solvents (NADES): Manufacture, Characteristics, and Their Significance as Designer Solvents

Pinky Satija, Anamika Chambyal, Gurleen Singh, Ritvik, Gurjaspreet Singh, Swati Devi and Jandeep Singh

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202401212

Chromatography free expeditious green synthesis of 3-hydroxy-2-pyrrolidone derivatives under eco-friendly conditions via the oxidation of benzyl amines without catalyst

Kajal Mal and Chhanda Mukhopadhyay

Journal of Molecular Structure, 2022, 1265, 133377
DOI: 10.1016/j.molstruc.2022.133377

Hansen Solubility Parameters Applied to the Extraction of Phytochemicals

Fábio Junior Moreira Novaes, Daliane Cláudia de Faria, Fabio Zamboni Ferraz and Francisco Radler de Aquino Neto

Plants, 2023, 12, 3008
DOI: 10.3390/plants12163008

Deep eutectic solvents as sustainable and extraordinary all-in-one systems for oxidative desulfurization

Fatemeh Armandsefat, Sholeh Hamzehzadeh, Najmedin Azizi and Saber Hosseini

Journal of Molecular Liquids, 2024, 410, 125560
DOI: 10.1016/j.molliq.2024.125560

Expedient multicomponent synthesis of a small library of some novel highly substituted pyrido[2,3-d]pyrimidine derivatives mediated and promoted by deep eutectic solvent and in vitro and quantum mechanical study of their antibacterial and antifungal activities

Reza Aryan, Hamid Beyzaei, Masoomeh Nojavan, Fatemeh Pirani, Hojat Samareh Delarami and Mahmood Sanchooli

Mol Divers, 2019, 23, 93
DOI: 10.1007/s11030-018-9859-7

Solvent‐Controlled Regioselectivity in Nucleophilic Substitution Reactions of 1‐X‐2,4‐Difluorobenzenes with Morpholine Using Deep Eutectic Solvents

Arun Valvi and Shraeddha Tiwari

ChemistrySelect, 2021, 6, 249
DOI: 10.1002/slct.202002806

Magnetic copper ferrite catalyzed homo‐ and cross‐coupling reaction of terminal alkynes under ambient atmosphere

Cui‐Ting Ma, Jiao‐Jiao Wang, Ai‐Dong Zhao, Qing‐Li Wang and Zhan‐Hui Zhang

Applied Organom Chemis, 2017, 31
DOI: 10.1002/aoc.3888

Low melting oxalic acid/proline mixture as dual solvent/catalyst for efficient synthesis of 13-aryl-13 H -benzo[ g ]benzothiazolo[2,3- b ]buinazoline-5,4-diones under microwave irradiation

Cui-Ting Ma, Peng Liu, Wei Wu and Zhan-Hui Zhang

Journal of Molecular Liquids, 2017, 242, 606
DOI: 10.1016/j.molliq.2017.07.060

An inclusive thermophysical and rheology portrayal of deep eutectic solvents (DES) for metal oxides dissolution enhancement

Anil Kumar Jangir, Piyush Sethy, Gunjan Verma, Pratap Bahadur and Ketan Kuperkar

Journal of Molecular Liquids, 2021, 332, 115909
DOI: 10.1016/j.molliq.2021.115909

Practical preparation of mono- and di-O-isopropylidene derivatives of monosaccharides and methyl 4,6-O-benzylidene glycosides from free sugars in a deep eutectic solvent

Sunil M. Rokade and Prakash M. Bhate

Journal of Carbohydrate Chemistry, 2017, 36, 20
DOI: 10.1080/07328303.2017.1347262

One-pot synthesis of per-O-acetylated hemiacetals from free sugars in a deep eutectic solvent

Sunil M. Rokade and Prakash M. Bhate

Carbohydrate Research, 2015, 416, 21
DOI: 10.1016/j.carres.2015.08.007

An effective combination of reusable Pd@MOF catalyst and deep eutectic solvents for high-performance C–C coupling reaction

Minh-Huy Dinh Dang, Trang Thi Thu Nguyen, Bao Quang Gia Le, Linh Ho Thuy Nguyen, Ngoc Xuan Dat Mai, My Van Nguyen, Phuong Hoang Tran and Tan Le Hoang Doan

Journal of Industrial and Engineering Chemistry, 2022, 111, 111
DOI: 10.1016/j.jiec.2022.03.041

Amidosulfonic acid supported on graphitic carbon nitride: novel and straightforward catalyst for Paal–Knorr pyrrole reaction under mild conditions

Asieh Azhdari, Najmedin Azizi, Haleh Sanaeishoar and Elham Tahanpesar

Monatsh Chem, 2021, 152, 625
DOI: 10.1007/s00706-021-02771-1

A green approach for synthesis of naphthoquinone-fused oxazine derivatives in water under ultrasonic irradiation

Ya-Qian Cao, Xin-Ran Li, Wei Wu, Dan Zhang, Zhan-Hui Zhang and Li-Ping Mo

Res Chem Intermed, 2017, 43, 3745
DOI: 10.1007/s11164-016-2854-7

Epoxidation of Soybean Oil Catalyzed by Deep Eutectic Solvents Based on the Choline Chloride–Carboxylic Acid Bifunctional Catalytic System

Ju Wang, Yong Liu, Zhining Zhou, Yan Fu and Jie Chang

Ind. Eng. Chem. Res., 2017, 56, 8224
DOI: 10.1021/acs.iecr.7b01677

Deep Eutectic Solvent of 1,3-Dimethylurea/L-(+)-Tartaric Acid for the Green Synthesis of (E)-2-Styrylquinoline-3-carboxylic Acid Derivatives

Yang Li, Jinding Yuan and Di Zhao

Chinese Journal of Organic Chemistry, 2023, 43, 3268
DOI: 10.6023/cjoc202301015

Hexafluoroisopropanol as solvent and promotor in the Paal-Knorr synthesis of N-substituted diaryl pyrroles

Robert H.E. Schirmacher, Daniel Rösch and Franziska Thomas

Tetrahedron, 2021, 83, 131985
DOI: 10.1016/j.tet.2021.131985

Deep eutectic solvents: designer fluids for chemical processes

Irfan Wazeer, Maan Hayyan and Mohamed K Hadj‐Kali

J of Chemical Tech & Biotech, 2018, 93, 945
DOI: 10.1002/jctb.5491

Synthesis and characterization of a lipase-friendly DES based on cholinium dihydrogen phosphate

María S. Álvarez, María A. Longo, Francisco J. Deive and Ana Rodríguez

Journal of Molecular Liquids, 2021, 340, 117230
DOI: 10.1016/j.molliq.2021.117230

Catalyst Free Synthesis of Bis(Indolyl)Methanes and 3,3‐Bis(Indolyl)oxindoles in Aqueous Ethyl Lactate

Ge Gao, Yi Han and Zhan‐Hui Zhang

ChemistrySelect, 2017, 2, 11561
DOI: 10.1002/slct.201702326

Multicomponent reaction in deep eutectic solvent for synthesis of substituted 1-aminoalkyl-2-naphthols

Najmedin Azizi and Mahtab Edrisi

Res Chem Intermed, 2017, 43, 379
DOI: 10.1007/s11164-016-2628-2

Choline chloride as an efficient catalyst for the synthesis of styryl-pyrazoles

Hardesh K. Maurya, Kripa Shankar Nainawat and Atul Gupta

Synthetic Communications, 2016, 46, 1044
DOI: 10.1080/00397911.2016.1185124

New magnetic-responsive deep eutectic catalyst based on Co2+/choline chloride for the synthesis of tetrahydro-pyrazolopyridines and pyrroles in water

Fatemeh Tamaddon and Ali Khorram

Journal of Molecular Liquids, 2020, 304, 112722
DOI: 10.1016/j.molliq.2020.112722

Urea decomposition: Efficient synthesis of pyrroles using the deep eutectic solvent choline chloride/urea

Lanfang Hu, Juan Luo, Dan Lu and Qiang Tang

Tetrahedron Letters, 2018, 59, 1698
DOI: 10.1016/j.tetlet.2018.03.043

Choline Chloride/ Urea as Mild Media for the Synthesis of the Chromonyl Amidodiester Fragments and Succinimide Derivatives

Hoda Jamaati, Saeed Balalaie, Maryam Kazemi Miraki, Frank Rominger and Hamid Reza Bijanzadeh

ChemistrySelect, 2019, 4, 9074
DOI: 10.1002/slct.201901893

Comparison of the Antibacterial Activity of Selected Deep Eutectic Solvents (DESs) and Deep Eutectic Solvents Comprising Organic Acids (OA‐DESs) Toward Gram‐Positive and Gram‐Negative Species

Tomasz Swebocki, Aleksandra M. Kocot, Alexandre Barras, Helena Arellano, Leila Bonnaud, Kamel Haddadi, Anne‐Laure Fameau, Sabine Szunerits, Magdalena Plotka and Rabah Boukherroub

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202303475

[Bmim]HSO4 loaded on Graphene Oxide: A Green and Retrievable Nanocatalyst for the Synthesis of Polysubstituted Pyrroles; Some of Which are Fluorinated

Maral Shekarchi and Farahnaz K. Behbahani

LOC, 2021, 18, 294
DOI: 10.2174/1570178617999200601170128

Synthesis of 3-Substituted Indoles Using Deep Eutectic Solvent and Ultrasound

Dnyaneshwar T. Nagre, Amol U. Khandebharad, Swapnil R. Sarda, Bharat K. Dhotre and Brijmohan R. Agrawal

Organic Preparations and Procedures International, 2021, 53, 278
DOI: 10.1080/00304948.2021.1875775

Sustainable and chemoselective N-Boc protection of amines in biodegradable deep eutectic solvent

Najmedin Azizi and Fatemeh Shirdel

Monatsh Chem, 2017, 148, 1069
DOI: 10.1007/s00706-016-1856-x

Magnesium Incorporated White Sandstone as a Green and Efficient Heterogeneous Catalyst for One‐Pot Synthesis of 1,2,3,4‐Tetrasubstituted Pyrroles

Ameneh Abolghassemi Fakhree, Zarrin Ghasemi, Aziz Shahrisa and Hossein Mostafavi

ChemistrySelect, 2019, 4, 2959
DOI: 10.1002/slct.201803794

Novel and highly efficient preparation of pyrroles using supported ionic liquid ILCF3SO3@SiO2 as a heterogeneous catalyst

Yang Liu and Yu Lin Hu

J IRAN CHEM SOC, 2018, 15, 1033
DOI: 10.1007/s13738-018-1300-8

A Decenary Update on the Deep Eutectic Solvents in Heterocyclic Scaffold Synthesis-A Green Solvent Approach

Kantharaju Kamanna, Krishnappa B. Badiger and Aravind Kamath

CGC, 2023, 10, 25
DOI: 10.2174/2213346110666230213113824

Magnetic nano-graphene oxide-supported molybdenum (Fe3O4/GO-Mo) as a green, efficient, and recyclable catalyst for synthesis of β-hydroxy hydroperoxides

Yu-Heng Liu, Hai-Chuan Hu, Zi-Chuan Ma, Yan-Fei Dong, Can Wang and Yun-Meng Pang

Monatsh Chem, 2018, 149, 551
DOI: 10.1007/s00706-017-2092-8

Efficient synthesis of benzo[h]carbazol[3,2‐b][1,6]naphthyridines

Yamuna Ezhumalai, Prabakaran Kumaresan, Zeller Matthias and Rajendra Prasad Karnam Jayarampillai

Journal of Heterocyclic Chem, 2022, 59, 1191
DOI: 10.1002/jhet.4459

Recent Advances in the Synthesis of Pyrroles

Sarosh Iqbal, Hina Rasheed, Rabiya Javed Awan, Ramsha Javed Awan, Asma Mukhtar and Mark G. Moloney

COC, 2020, 24, 1196
DOI: 10.2174/1385272824999200528125651

Passerini three-component cascade reactions in deep eutectic solvent: an environmentally benign and rapid system for the synthesis of α-acyloxyamides

Ahmad Shaabani, Ronak Afshari and Seyyed Emad Hooshmand

Res Chem Intermed, 2016, 42, 5607
DOI: 10.1007/s11164-015-2390-x

Deep eutectic solvents in biomass pretreatment for green approach: a comprehensive review

Munir Hussain, Hafiz Tanveer Ashraf, Vikul Vasudev, Sohail Yasin, Muhammad Imran Jamil, Menahil Saleem, Tariq Aziz, Easir Al Afroz, Zhu Feichao, Zhang Huapeng and Yu Bin

Polym. Bull., 2025
DOI: 10.1007/s00289-025-05955-5

Microwave assisted synthesis of 5-ethoxymethylfurfural in one pot from d-fructose by using deep eutectic solvent as catalyst under mild condition

Anil B. Gawade and Ganapati D. Yadav

Biomass and Bioenergy, 2018, 117, 38
DOI: 10.1016/j.biombioe.2018.07.008

Deep Eutectic Solvents (DESs): Emerging viable solvent systems for transition-metal-catalyzed cross-coupling reactions

Sharda Pasricha, Pragya Gahlot, T.M. Rangarajan, Shikha, Deepak, Harsh Pahuja, Divya Yadav, Pratham, Khushboo Pilania and Sachid Anand

Journal of Molecular Liquids, 2025, 426, 127287
DOI: 10.1016/j.molliq.2025.127287

Greener and Additive-Free Reactions in Deep Eutectic Solvent: One-Pot, Three-Component Synthesis of Highly Substituted Pyridines

Najmedin Azizi and Mehran Shahiri Haghayegh

ChemistrySelect, 2017, 2, 8870
DOI: 10.1002/slct.201701682

Recent Advances in Utilization of Deep Eutectic Solvents: An Environmentally Friendly Pathway for Multi-component Synthesis

Ajay Thakur, Monika Verma, Ruchi Bharti and Renu Sharma

COC, 2022, 26, 299
DOI: 10.2174/1385272826666220126165925

Catalyst-Free, Visible-Light Promoted One-Pot Synthesis of Spirooxindole-Pyran Derivatives in Aqueous Ethyl Lactate

Mo Zhang, Qiu-Yang Fu, Ge Gao, He-Ye He, Ying Zhang, Yin-Su Wu and Zhan-Hui Zhang

ACS Sustainable Chem. Eng., 2017, 5, 6175
DOI: 10.1021/acssuschemeng.7b01102

A Bird's‐Eye View on Deep Eutectic Solvent‐Mediated Multicomponent Synthesis of N‐Heterocycles

Lokesh Kumar S, Anushka Servesh, Yash Kumar Sriwastav, Sanjaybala Balasubramanian, Sumaiya Tabassum and Santhosh Govindaraju

ChemistrySelect, 2023, 8
DOI: 10.1002/slct.202301054

NiO Nanoparticles: Efficient Catalyst for Four Component Coupling Reaction for Synthesis of Substituted Pyrroles

Aravind L. Gajengi and Bhalchandra M. Bhanage

Catal Lett, 2016, 146, 1341
DOI: 10.1007/s10562-016-1762-1

Deep eutectic solvents as reusable catalysts and promoter for the greener syntheses of small molecules: Recent advances

Seyyed Emad Hooshmand, Sandeep Kumar, Indra Bahadur, Thishana Singh and Rajender S. Varma

Journal of Molecular Liquids, 2023, 371, 121013
DOI: 10.1016/j.molliq.2022.121013

Visible Light‐Mediated Multicomponent Synthesis of Spirooxindole‐Linked Fused Pyrans: An Eco‐Friendly One‐Pot Strategy

Nurabul Mondal, Darshika Singh, Vidya Kumari and Lokman H. Choudhury

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202402549

l-Tryptophan-catalyzed Paal–Knorr pyrrole cyclocondensation: an efficient, clean and recyclable organocatalyst

Kioumars Aghapoor, Farshid Mohsenzadeh, Hossein Reza Darabi, Hani Sayahi and Yadollah Balavar

Res Chem Intermed, 2016, 42, 407
DOI: 10.1007/s11164-015-2026-1

ChemInform Abstract: Deep Eutectic Solvent Based on Choline Chloride and Malonic Acid as an Efficient and Reusable Catalytic System for One‐Pot Synthesis of Functionalized Pyrroles.

Hai‐Chuan Hu, Yu‐Heng Liu, Bao‐Le Li, Zhen‐Shui Cui and Zhan‐Hui Zhang

ChemInform, 2015, 46
DOI: 10.1002/chin.201525145

Hydrophobic Deep Eutectic Solvents Incorporating Trioctylphosphine Oxide: Advanced Liquid Extractants

Mark Gilmore, Éadaoin N. McCourt, Francis Connolly, Peter Nockemann, Małgorzata Swadźba-Kwaśny and John D. Holbrey

ACS Sustainable Chem. Eng., 2018, 6, 17323
DOI: 10.1021/acssuschemeng.8b04843

Use of deep eutectic solvents as catalyst: A mini-review

Ayşe Ezgi Ünlü, Azime Arıkaya and Serpil Takaç

Green Processing and Synthesis, 2019, 8, 355
DOI: 10.1515/gps-2019-0003

Deep Eutectic Solvents as Catalysts in the Synthesis of Active Pharmaceutical Ingredients and Precursors

Chiara Falcini and Gonzalo de Gonzalo

Catalysts, 2024, 14, 120
DOI: 10.3390/catal14020120

Deep Eutectic Solvents: The Organic Reaction Medium of the Century

Diego A. Alonso, Alejandro Baeza, Rafael Chinchilla, Gabriela Guillena, Isidro M. Pastor and Diego J. Ramón

Eur J Org Chem, 2016, 2016, 612
DOI: 10.1002/ejoc.201501197

Multicomponent Strategy for the Preparation of Pyrrolo[1,2‐a]pyrimidine Derivatives under Catalyst‐Free and Microwave Irradiation Conditions

Zhan Xun, Xian Feng, Jianjun Wang, Daqing Shi and Zhibin Huang

Chin. J. Chem., 2016, 34, 696
DOI: 10.1002/cjoc.201600142

Deep Eutectic Solvent/Lipase: Two Environmentally Benign and Recyclable Media for Efficient Synthesis of N-Aryl Amines

Preeti Lalit Pant and Ganapati Subray Shankarling

Catal Lett, 2017, 147, 1371
DOI: 10.1007/s10562-017-2046-0

Visible Light-Mediated Four-Component synthesis of Polyfunctionalized pyrroles using Eosin-Y via the HAT process

Faezeh Ahmadi, Monire Shariatipour, Masoumeh Jadidi Nejad and Akbar Heydari

Journal of Photochemistry and Photobiology A: Chemistry, 2024, 457, 115863
DOI: 10.1016/j.jphotochem.2024.115863

Choline chloride/urea as a deep eutectic solvent/organocatalyst promoted three-component synthesis of 3-aminoimidazo-fused heterocycles via Groebke–Blackburn–Bienayme process

Ahmad Shaabani and Seyyed Emad Hooshmand

Tetrahedron Letters, 2016, 57, 310
DOI: 10.1016/j.tetlet.2015.12.014

Thermal stability of choline chloride deep eutectic solvents by TGA/FTIR-ATR analysis

Noemí Delgado-Mellado, Marcos Larriba, Pablo Navarro, Victoria Rigual, Miguel Ayuso, Julián García and Francisco Rodríguez

Journal of Molecular Liquids, 2018, 260, 37
DOI: 10.1016/j.molliq.2018.03.076