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Correction: An immunological electrospun scaffold for tumor cell killing and healthy tissue regeneration

Xingzhi Liua, Hongbo Zhangbcdef, Ruoyu Chenga, Yanzheng Gua, Yin Yind, Zhiyong Suna, Guoqing Pana, Zhongbin Dengi, Huilin Yanga, Lianfu Dengbc, Wenguo Cui*bc, Hélder A. Santos*gh and Qin Shi*aj
aDepartment of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedic Institute, Soochow University, 708 Renmin Road, Suzhou, Jiangsu 215006, P. R. China. E-mail: shiqin@suda.edu.cn
bShanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai 200025, P. R. China. E-mail: wgcui80@hotmail.com
cState Key Laboratory of Molecular Engineering of Polymers, Fudan University, No. 220 Handan Road, Shanghai 200433, P. R. China
dAnimal Experimental Center, Soochow University, 99 Renai Road, Suzhou, Jiangsu 215023, P. R. China
eDepartment of Pharmaceutical Sciences Laboratory, Åbo Akademi University, FI-00520, Finland
fTurku Center for Biotechnology, University of Turku and Åbo Akademi University, FI-00520, Finland
gDrug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki FI-00014, Finland
hHelsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki FI-00014, Finland. E-mail: helder.santos@helsinki.fi
iDepartment of Medicine, James Graham Brown Cancer Center, University of Louisville, 505 South Hancock Street, Louisville, KY 40202, USA
jKey Laboratory of Stem Cells and Biomedical Materials of Jiangsu Province and Chinese Ministry of Science and Technology, 199 Renai Rd, Suzhou, 215123, China

Received 7th October 2025 , Accepted 7th October 2025

First published on 14th October 2025


Abstract

Correction for ‘An immunological electrospun scaffold for tumor cell killing and healthy tissue regeneration’ by Xingzhi Liu et al., Mater. Horiz., 2018, 5, 1082–1091, https://doi.org/10.1039/C8MH00704G.


The authors regret errors in Fig. 2c and in Fig. 4c.
image file: d5mh90127h-f2.tif
Fig. 2 The anti-proliferation effect of CD40mAb released from PLLA-PDA-CD40mAb scaffolds for 24 h towards MDA-MB-231 cells. (a) Cell viability of MDA-MB-231. (b) The relative gene expressions of Bax and Bcl-2 of MDA-MB-231 cells (data are represented as fold changes normalized by cells cultured in cell medium). (c) Flow cytometry assay (FCA) for MDA-MB-231 cell apoptosis. Control: cells seeding onto the plate (compared with the PLLA group; *p < 0.05).

image file: d5mh90127h-f4.tif
Fig. 4 In vivo anticancer efficiency of PLLA-PDA-CD40mAb membranes. (a) The representative photographs of the tumors after various treatments and quantification of tumor masses in the different groups indicated. (b) The volumes of tumor masses. (c) H&E stained images, immunohistochemical analysis and TUNEL apoptosis assay (green: apoptotic cells; blue: nuclei) of tumor tissues after membrane-treated therapy. (d) Quantification of the expression of Ki67, TUNEL, H&E assay (***p < 0.001).

In Fig. 2c the incorrect data was used for PLLA-PDA and in Fig. 4c the incorrect image was used for Ki67 PLLA-PDA-IgG.

The corrected figures are shown here.

Independent experts have viewed the corrected figures and the raw data, and they have confirmed that the corrected figures are consistent with the discussions and conclusions presented.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


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