Themed collection Contributions from the chemical industry
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Greening the synthesis of peptide therapeutics: an industrial perspective
This review highlights the efforts made to date to promote greener peptide synthesis, from an industrial perspective.
RSC Adv., 2020,10, 42457-42492
https://doi.org/10.1039/D0RA07204D
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Understanding GPCR recognition and folding from NMR studies of fragments
Cotranslational protein folding is a vectorial process, and for membrane proteins, N-terminal helical segments are the first that become available for membrane insertion. Here fragments corresponding to these segments are investigated by NMR.
RSC Adv., 2018,8, 9858-9870
https://doi.org/10.1039/C8RA01520A
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New N-acyl amino acid-functionalized biodegradable polyesters for pharmaceutical and biomedical applications
Aminoacyl PGA: a biodegradable polyester modified with amino acids to provide a range of physicochemical characteristics for interaction with drugs.
RSC Adv., 2016,6, 109401-109405
https://doi.org/10.1039/C6RA21464A
Self-assembled collagen-like-peptide implants as alternatives to human donor corneal transplantation
PEG-conjugated collagen-like peptides promote corneal regeneration in a pig cornea.
RSC Adv., 2016,6, 55745-55749
https://doi.org/10.1039/C6RA08895C
Copper-catalysed reductive amination of nitriles and organic-group reductions using dimethylamine borane
A mild convenient method for the aqueous reduction of a range of organic functionalities and the reductive amination of nitriles using a heterogeneous copper catalyst formed in situ.
RSC Adv., 2014,4, 51845-51849
https://doi.org/10.1039/C4RA11193A
Synthesis of 3-aryl-1H-indazoles via iridium-catalysed C–H borylation and Suzuki–Miyaura coupling
The regioselective iridium-catalysed C3-borylation of 1H-indazoles has been achieved. Subsequent Suzuki–Miyaura coupling of the boronate esters with aryl chlorides, bromides and iodides affords 3-aryl-1H-indazoles in good yields.
RSC Adv., 2014,4, 27726-27729
https://doi.org/10.1039/C4RA04235B
Copper-catalysed amidation of 2-chloro-pyridines
The simple and inexpensive N,N-dimethylcyclohexane-1,2-diamine/CuI catalytic system provides a versatile, easy and efficient access to an array of N-(2-pyridin-2-yl)-amides from 2-chloro-pyridine derivatives.
RSC Adv., 2013,3, 18787-18790
https://doi.org/10.1039/C3RA43368D
Synthesis of 2-substituted quinazolines via iridium catalysis
An iridium-catalysed hydrogen transfer reaction was successfully applied in the synthesis of 2-substituted quinazolines in moderate yields starting from aldehydes or alcohols with 2-aminobenzylamines.
RSC Adv., 2013,3, 334-336
https://doi.org/10.1039/C2RA22278G
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Automated glycan assembly of Streptococcus pneumoniae type 14 capsular polysaccharide fragments
A streamlined automated synthesis for S. pneumoniae type 14 and Group B Streptococcus type III capsular oligosaccharides with only one set of three building blocks is presented. Competitive ELISA provides some insight into minimal epitope.
RSC Adv., 2020,10, 23668-23674
https://doi.org/10.1039/D0RA01803A
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Lithium metal deposition/dissolution under uniaxial pressure with high-rigidity layered polyethylene separator
The use of a high rigidity separator and application of an appropriate amount of pressure are effective approaches to control lithium metal growth and improve its cycle performance.
RSC Adv., 2020,10, 17805-17815
https://doi.org/10.1039/D0RA02788J
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Applicability of electro-osmotic flow for the analysis of the surface zeta potential
Detail comparison of two different electrokinetic phenomena EOF and SP method for the SZP determination with taking into account various materials with different surface and bulk properties.
RSC Adv., 2020,10, 6777-6789
https://doi.org/10.1039/C9RA10414C
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A strained alkyne-containing bipyridine reagent; synthesis, reactivity and fluorescence properties
A bipyridyl reagent containing a strained alkyne 7, reacts with benzyl azide to give a significantly more flexible product 10 and an increase in fluorescence is observed. Upon addition of Zn(II), the fluorescence is enhanced further.
RSC Adv., 2019,9, 36154-36161
https://doi.org/10.1039/C9RA06866J
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Antibacterial effect of boron nitride flakes with controlled orientation in polymer composites
Vertically oriented boron nitride flakes on a polymer surface exhibit bactericidal activity.
RSC Adv., 2019,9, 33454-33459
https://doi.org/10.1039/C9RA06773F
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Ionic association analysis of LiTDI, LiFSI and LiPF6 in EC/DMC for better Li-ion battery performances
Insight is given on the type of ion-pairs that could be formed in EC/DMC by Li-salts LiTDI, LiFSI and LiPF6.
RSC Adv., 2019,9, 4599-4608
https://doi.org/10.1039/C8RA08430K
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Biocatalytic asymmetric Michael addition reaction of L-arginine to fumarate for the green synthesis of N-(([(4S)-4-amino-4-carboxy-butyl]amino)iminomethyl)-L-aspartic acid lithium salt (L-argininosuccinic acid lithium salt)
The biocatalytic asymmetric Michael addition of L-arginine to fumarate using argininosuccinate lyase (ASL) has enabled the synthesis of the key metabolite L-argininosuccinic acid lithium salt 1 for the first time, with excellent yield and purity.
RSC Adv., 2017,7, 48952-48957
https://doi.org/10.1039/C7RA10236D
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Catalytic glycerol hydrogenolysis to 1,3-propanediol in a gas–solid fluidized bed
We report the gas-phase hydrogenolysis of glycerol to 1,3-propanediol over Pt/WO3/Al2O3 in a fluidized bed operating above 240 °C and at ambient pressure.
RSC Adv., 2017,7, 3853-3860
https://doi.org/10.1039/C6RA27248G
Green alternative solvents for the copper-catalysed arylation of phenols and amides
The use of alkyl acetates as green organic solvents for the Cu-catalysed arylation of phenols and amides is reported.
RSC Adv., 2016,6, 70025-70032
https://doi.org/10.1039/C6RA02265K
The effect of protein concentration on the viscosity of a recombinant albumin solution formulation
The effect of protein concentration on solution viscosity in a commercially available biopharmaceutical formulation of recombinant albumin (rAlbumin) was studied.
RSC Adv., 2016,6, 15143-15154
https://doi.org/10.1039/C5RA21068B
Catalytic CO2 hydrogenation to formic acid over carbon nanotube-graphene supported PdNi alloy catalysts
Pure formic acid was produced via CO2 hydrogenation over a heterogeneous PdNi alloy catalyst on carbon nanotube-graphene support in water solvent without a base additive.
RSC Adv., 2015,5, 105560-105566
https://doi.org/10.1039/C5RA21017H
Synthesis and serum protein binding of novel ring-substituted harmine derivatives
Potential anticancer derivatives of the β-carboline alkaloid harmine exhibit substituent dependent serum protein binding.
RSC Adv., 2015,5, 53809-53818
https://doi.org/10.1039/C5RA06426K
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Synthesis and morphological characterization of phenyl-modified macroporous–mesoporous hybrid silica monoliths
We present a comprehensive approach to characterize the one-pot synthesis, macropore space morphology, and chromatographic performance of phenyl-modified macro–mesoporous silica monoliths.
RSC Adv., 2015,5, 20283-20294
https://doi.org/10.1039/C4RA16519E
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First synthesis of naphthalene annulated oxepins
Highly condensed oxepins have been prepared in good yields from their corresponding diols by etherification using p-toluenesulfonic acid.
RSC Adv., 2014,4, 60473-60477
https://doi.org/10.1039/C4RA10652K
About this collection
We are very pleased to present our 10th Anniversary collection on contributions from the chemical industry!Looking back over the last 10 years, we would like to showcase some of the very best articles that have been published in RSC Advances. Many of these papers have been cited hundreds of times, providing valuable advances for further research, and some continue to be among the journal’s most downloaded articles as of today.
We hope you enjoy our 10th Anniversary collection on contributions from the chemical industry!