Recent advances in the (3+2) cycloaddition of azomethine ylide

Abstract

Nitrogen-containing heterocyclic compounds are some of the most significant compounds that are produced artificially or naturally. These heterocyclic rings are virtually always present in the biological system, from the smallest eukaryotes to the largest prokaryotic cell. The compounds that are synthesized by the help of azomethine ylides that fall in this category are quite important because they bind with our biological living cells. One cannot ignore the possibility of using different derivatives of these azomethine ylide skeletons not only as medications but also as organo-electroznic materials, fluorescent probes, etc. The synthesis of several scaffold derivatives during the last few years utilizing a range of methods is the main topic of this review. We outlined the precise synthetic routes for each technique and highlighted the yield variance from a variety of perspectives.