Issue 14, 2019
From the journal:

Organic Chemistry Frontiers

Bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]−: synthesis, characterization and its application for trifluoromethylation of activated heteroaryl bromides, chlorides and iodides†

He Liua  and  Qilong Shen ORCID logo *a  

* Corresponding authors

a Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, P. R. China
E-mail: shenql@sioc.ac.cn

Abstract

The synthesis and characterization of a bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]− and its reactions with a variety of activated heteroaryl bromides, chlorides and iodides were described. These results showed that complex [Ph4P]+[Cu(CF3)2]− can serve as a trifluoromethylating reagent.

Graphical abstract: Bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]−: synthesis, characterization and its application for trifluoromethylation of activated heteroaryl bromides, chlorides and iodides

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Article information

DOI
https://doi.org/10.1039/C9QO00527G
Article type
Research Article
Submitted
18 Apr 2019
Accepted
11 May 2019
First published
13 May 2019

Org. Chem. Front., 2019,6, 2324-2328

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Bistrifluoromethylated organocuprate [Ph4P]+[Cu(CF3)2]−: synthesis, characterization and its application for trifluoromethylation of activated heteroaryl bromides, chlorides and iodides

H. Liu and Q. Shen, Org. Chem. Front., 2019, 6, 2324 DOI: 10.1039/C9QO00527G

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