Rapid and selective DNA-based detection of melamine using α-hemolysin nanopores

Yingying Sheng; Yi You; Zhong Cao; Lei Liu; Hai-Chen Wu

doi:10.1039/C8AN00580J

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Rapid and selective DNA-based detection of melamine using α-hemolysin nanopores†

Yingying Sheng,^ab Yi You,^a Zhong Cao,*^a Lei Liu

*^b and Hai-Chen Wu

Author affiliations

* Corresponding authors

^a Collaborative Innovation Center of Micro/nano Bio-sensing and Food Safety Inspection, Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation, School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha 410114, China
E-mail: zhongcao2004@163.com

^b Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China
E-mail: leiliu@ihep.ac.cn
Fax: +86 10 88235745
Tel: +86 10 88235745

Abstract

We have developed a rapid and selective approach for the detection of melamine based on simple DNA probes and α-hemolysin nanopores. The limit of detection can be as low as 10 pM.

This article is part of the themed collection: In celebration of Chinese New Year 2020

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Article information

DOI: https://doi.org/10.1039/C8AN00580J
Article type: Paper
Submitted: 28 Mar 2018
Accepted: 19 Apr 2018
First published: 20 Apr 2018

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Analyst, 2018,143, 2411-2415

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Rapid and selective DNA-based detection of melamine using α-hemolysin nanopores

Y. Sheng, Y. You, Z. Cao, L. Liu and H. Wu, Analyst, 2018, 143, 2411 DOI: 10.1039/C8AN00580J

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Rapid and selective DNA-based detection of melamine using α-hemolysin nanopores†

Abstract

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Rapid and selective DNA-based detection of melamine using α-hemolysin nanopores

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