Issue 80, 2017
From the journal:

RSC Advances

Synthesis and evaluation of a tetra[6,7]quinoxalinoporphyrazine-based near infrared photosensitizer†

Pin Shao,a   Shaojuan Zhang,a   Shudong Hu,b   Le Han,c   Ningyang Jia*d  and  Mingfeng Bai ORCID logo *aefg  

* Corresponding authors

a Department of Radiology, University of Pittsburgh, 100 Technology Drive, Pittsburgh, PA 15219, USA
E-mail: mingfeng.bai@vanderbilt.edu

b Department of Radiology, The Affiliated Renmin Hospital, Jiangsu University, Zhenjiang, Jiangsu, China

c Vanderbilt University Institute of Imaging Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA

d Department of Radiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China

e Department of Medicine, University of Pittsburgh, 3501 Fifth Ave, Pittsburgh, PA 15213, USA

f Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA

g University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA

Abstract

Here we report a near infrared, water-soluble, functional and dendrimeric photosensitizer (PS) based on quinoxalinoporphyrazine structure. The photophysical properties and in vitro photodynamic therapy results suggest that this quinoxalinoporphyrazine-based dendrimer may serve as an efficient near infrared (NIR) PS platform.

Graphical abstract: Synthesis and evaluation of a tetra[6,7]quinoxalinoporphyrazine-based near infrared photosensitizer

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Article information

DOI
https://doi.org/10.1039/C7RA06348B
Article type
Paper
Submitted
06 Jun 2017
Accepted
13 Oct 2017
First published
30 Oct 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 50555-50561

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Synthesis and evaluation of a tetra[6,7]quinoxalinoporphyrazine-based near infrared photosensitizer

P. Shao, S. Zhang, S. Hu, L. Han, N. Jia and M. Bai, RSC Adv., 2017, 7, 50555 DOI: 10.1039/C7RA06348B

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