Issue 90, 2015
From the journal:

RSC Advances

SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein†

Xiaoling Wu,a   Pan Fu,a   Wei Ma,a   Liguang Xu,a   Hua Kuanga  and  Chuanlai Xu*a  

* Corresponding authors

a State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, People's Republic of China
E-mail: xcl@jiangnan.edu.cn

Abstract

SERS-active silver nanoparticle trimers were assembled in this study for the first time, through the aptamer of a cancer biomarker, alpha fetoprotein (AFP). It was successfully used for the sub-attomolar detection of AFP, with a limit of detection as low as 0.097 aM, which is the lowest reported so far.

Graphical abstract: SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein

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Article information

DOI
https://doi.org/10.1039/C5RA12629K
Article type
Communication
Submitted
30 Jun 2015
Accepted
21 Aug 2015
First published
24 Aug 2015

RSC Adv., 2015,5, 73395-73398

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SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein

X. Wu, P. Fu, W. Ma, L. Xu, H. Kuang and C. Xu, RSC Adv., 2015, 5, 73395 DOI: 10.1039/C5RA12629K

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