Issue 7, 2015
From the journal:

Organic Chemistry Frontiers

Pd(ii)-catalyzed intermolecular enantioselective hydroamination of styrenes†

Feng Yu,a   Pinhong Chen*a  and  Guosheng Liu*a  

* Corresponding authors

a State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, 345 Lingling Road, Shanghai, China
E-mail: pinhongchen@sioc.ac.cn, gliu@mail.sioc.ac.cn
Fax: +86-21-64166128
Tel: +86-21-54925346

Abstract

A Pd-catalyzed intermolecular asymmetric hydroamination of styrenes was developed to give various chiral benzyl amides exclusively, in which the oxidation-stable pyridine-oxazoline was used as the chiral ligand to provide moderate to good enantioselectivities.

Graphical abstract: Pd(ii)-catalyzed intermolecular enantioselective hydroamination of styrenes

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Article information

DOI
https://doi.org/10.1039/C5QO00096C
Article type
Research Article
Submitted
25 Mar 2015
Accepted
07 May 2015
First published
07 May 2015

Org. Chem. Front., 2015,2, 819-822

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Pd(II)-catalyzed intermolecular enantioselective hydroamination of styrenes

F. Yu, P. Chen and G. Liu, Org. Chem. Front., 2015, 2, 819 DOI: 10.1039/C5QO00096C

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