Issue 18, 2011
From the journal:

Chemical Communications

Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study†

Nanda Gopal Sahoo,a   Hongqian Bao,a   Yongzheng Pan,a   Mintu Pal,a   Mitali Kakran,a   Henry Kuo Feng Cheng,a   Lin Li*a  and  Lay Poh Tanb  

* Corresponding authors

a School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore
E-mail: mlli@ntu.edu.sg

b School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore

Abstract

Carbon nanomaterials such as multiwalled carbon nanotubes (MWCNTs) and graphene oxide (GO) have been functionalized by highly hydrophilic and biocompatible poly(vinyl alcohol) (PVA) for loading and delivery of an anticancer drug, camptothecin (CPT). For the first time, CPT was loaded onto MWCNT–PVA and GO–PVA through π–π interactions and its capability to kill human breast and skin cancer cells was investigated.

Graphical abstract: Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC00075F
Article type
Communication
Submitted
05 Jan 2011
Accepted
14 Mar 2011
First published
30 Mar 2011

Chem. Commun., 2011,47, 5235-5237

Permissions

Request permissions

Functionalized carbon nanomaterials as nanocarriers for loading and delivery of a poorly water-soluble anticancer drug: a comparative study

N. G. Sahoo, H. Bao, Y. Pan, M. Pal, M. Kakran, H. K. F. Cheng, L. Li and L. P. Tan, Chem. Commun., 2011, 47, 5235 DOI: 10.1039/C1CC00075F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements