Themed collection Recent Review Articles


Mechanism of methane activation and graphene growth on oxide ceramics
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00569H
Biomimetic ion channels with subnanometer sizes for ion sieving: a mini-review
The ion-selective transport property of biological systems has inspired the development of biomimetic ion channels. This mini-review highlights the mechanisms, recent fabrication strategies and applications of biomimetic ion channels.
Nanoscale, 2025,17, 9021-9039
https://doi.org/10.1039/D5NR00758E
Smart MXene-based microrobots for targeted drug delivery and synergistic therapies
This review emphasizes the groundbreaking potential of MXene-based microrobots in developing targeted drug delivery and synergistic therapeutic approaches.
Nanoscale, 2025,17, 9040-9056
https://doi.org/10.1039/D4NR05160B
Cu-based bimetallic catalysts for electrochemical CO2 reduction: before and beyond the tandem effect
Cu-based bimetallic catalysts show enhanced electrochemical CO2 reduction performance via the tandem effect. This review traces their progress, highlighting design advances, mechanisms, and challenges to guide efficient CO2 conversion.
Nanoscale, 2025,17, 9057-9071
https://doi.org/10.1039/D4NR04790G
Functionalization of rod-shaped plant viruses for biomedical applications
This review explores the development of biomedical nanomaterials based on rod-shaped plant viruses, providing insights into the design of innovative biomaterials for applications related to drug delivery, bioimaging and immune-therapy. Created in https://BioRender.com.
Nanoscale, 2025,17, 9072-9085
https://doi.org/10.1039/D4NR05354K
Polymer Additives in Liquid Electrolyte for Advanced lithium Batteries
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00470E

Recent progress of noble metal-based nanozymes: structural engineering and biomedical applications
This review highlights the recent progress in structural engineering of noble metal-based nanozymes and their enzyme-like properties in various enzyme-mimicking reactions and diverse biomedical applications.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05514D

Spin effects in metal halide perovskite semiconductors
This review explores the spin effects in both achiral and chiral metal halide perovskites and their opto-spintronic applications.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00127G

Hydrogen bubble evolution and its induced mass transfer on zinc electrodes in alkaline and neutral media
Hydrogen bubble evolution presents both challenges and opportunities in Zn-based batteries. While bubble evolution induces electrode instability and dendrite formation, it can also optimize mass transfer through controlled fluid dynamics.
Nanoscale, 2025,17, 8453-8465
https://doi.org/10.1039/D4NR05108D
Flexible fibrous electrodes for implantable biosensing
This review explores advancements, applications, challenges, and future prospects of flexible fibrous electrodes for implantable biosensing, highlighting their potential in biomedical monitoring and human–machine interfaces. Images reproduced with permission, full details in paper.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04542D

Characterisation of polymeric nanoparticles for drug delivery
Polymeric nanoparticles represent an innovative approach to drug delivery, particularly for addressing complex diseases like cancer.
Nanoscale, 2025,17, 7738-7752
https://doi.org/10.1039/D5NR00071H
External strategies for enhanced sensing performance of self-powered polyvinylidene fluoride-based sensors
External strategies such as electrode design, stress/heat transfer improvements, microstructure optimization, and multifunctional synergy show great potential for improving sensing performance of PVDF-based sensors. Images reproduced with permission, full details in paper.
Nanoscale, 2025,17, 6981-6992
https://doi.org/10.1039/D4NR05200E

Sustainable nanofibrous membranes for air filtration, water purification and oil removal
The increasing demand for sustainable solutions to address environmental and energy challenges has driven the development of advanced materials. This paper highlights recent advancements in the development of sustainable nanofibrous membranes.
Nanoscale, 2025,17, 6427-6447
https://doi.org/10.1039/D4NR04673K
Recent advances in multimodal mechanoluminescent sensors enabled by nanostructure design
Multifunctional coupling and signal decoupling achieved through nanostructure and supramolecule design, enable multimodal mechanoluminescent materials to play an increasingly important role in interdisciplinary applications and cutting-edge fields.
Nanoscale, 2025,17, 6414-6426
https://doi.org/10.1039/D4NR04875J
Multifunctional DNA nanomaterials: a new frontier in rheumatoid arthritis diagnosis and treatment
DNA nanomaterials offer promising advancements in addressing the challenges of rheumatoid arthritis (RA) through targeted drug delivery, biomarker detection, and therapeutic innovation.
Nanoscale, 2025,17, 4974-4999
https://doi.org/10.1039/D4NR04013A
Colloidal semiconductor quantum shells for solution-processed laser applications
Laser diodes based on solution-processed semiconductor quantum dots (QDs) present an economical and color-tunable alternative to traditional epitaxial lasers.
Nanoscale, 2025,17, 3698-3707
https://doi.org/10.1039/D4NR04653F
Leveraging the dual role of ROS in liver diseases with nanomaterials: clearing and amplifying for therapy
The dual role of ROS in liver diseases, and the potential of nanomaterials with catalytic activity for therapeutic applications are examined.
Nanoscale, 2025,17, 3688-3697
https://doi.org/10.1039/D4NR04469J
NIR-II upconversion nanomaterials for biomedical applications
This review provides a comprehensive overview of recent biomedical applications of upconversion nanomaterials specifically within the near-infrared two-region (NIR-II) window (1000–1700 nm).
Nanoscale, 2025,17, 2985-3002
https://doi.org/10.1039/D4NR04445B
Mathematically inspired structure design in nanoscale thermal transport
Mathematically inspired structure design has emerged as a powerful approach for tailoring material properties, especially in nanoscale thermal transport, with promising applications both within this field and beyond.
Nanoscale, 2025,17, 3003-3013
https://doi.org/10.1039/D4NR04385E

Advances in integrated power supplies for self-powered bioelectronic devices
The emerging integrated power supplies for self-powered bioelectronic devices over the past few years are summarized. Additionally, the challenges and future perspectives in self-powered device design and manufacturing are also indicated.
Nanoscale, 2025,17, 2423-2437
https://doi.org/10.1039/D4NR04645E

Design strategies and performance enhancements of PVDF-based flexible electrolytes for high-performance all-solid-state lithium metal batteries
Lithium metal is considered one of the most promising anode materials for lithium batteries due to its high theoretical specific capacity (3860 mA h g−1) and low redox potential (−3.04 V).
Nanoscale, 2025,17, 2408-2422
https://doi.org/10.1039/D4NR04583A
Organic semiconductor bulk heterojunctions for solar-to-chemical conversion: recent advances and challenges
This minireview highlights recent progress in BHJ-based photoelectrochemical cells and photocatalysts for solar-to-chemical conversions.
Nanoscale, 2025,17, 1889-1921
https://doi.org/10.1039/D4NR03938F
Chiral nanomaterials as vaccine adjuvants: a new horizon in immunotherapy
Chiral nanomaterials are emerging as a promising class of vaccine adjuvants with the potential to significantly enhance vaccine efficacy, especially in the context of cancer immunotherapy.
Nanoscale, 2025,17, 1932-1935
https://doi.org/10.1039/D4NR03542A

Advances in simulating dilute alloy nanoparticles for catalysis
Dilute and single-atom alloy catalysts have attracted tremendous attention in heterogeneous catalysis. Herein, we discuss recent progress on simulating their stability and catalytic behavior.
Nanoscale, 2025,17, 1936-1953
https://doi.org/10.1039/D4NR03761H
Near-infrared circularly polarized luminescence enabled by chiral inorganic nanomaterials
We summarize the latest developments in NIR-CPL generated by chiral inorganic nanomaterials and provide new perspectives for constructing NIR-CPL materials and developing new applications for chiral nanomaterials.
Nanoscale, 2025,17, 1922-1931
https://doi.org/10.1039/D4NR03743J
Bioinspired solid-state nanochannels for molecular analysis
Solid-state nanochannel sensors consisting of recognition elements and nanochannels are capable of detecting a wide range of small molecules including gas molecules, drug molecules and biomolecules.
Nanoscale, 2025,17, 1225-1237
https://doi.org/10.1039/D4NR03711A
Unveiling nanoparticle–immune interactions: how super-resolution imaging illuminates the invisible
This mini-review focuses on how super-resolution techniques uncover the detailed interactions between nanoparticles and immune cells.
Nanoscale, 2025,17, 1213-1224
https://doi.org/10.1039/D4NR03838J

Chirality generation on carbon nanosheets by chemical modification
Chirality is an intriguing property of molecules, and exciting area of study involves the generation of chirality in nanographenes (NGs), also known as graphene quantum dots.
Nanoscale, 2025,17, 774-787
https://doi.org/10.1039/D4NR02952F
Research progress of transition metal catalysts for electrocatalytic Ethylene glycol oxidation
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05000B
Quantum dot-based memristors for information processing and artificial intelligence applications
Research and progress in quantum dot memristors.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00136F
Electrospun freestanding anodes for metal-ion batteries: structural design and application
This review highlights the structural design of freestanding nanofibrous anodes for a thorough understanding of the synergistic effect between structural design and anode active materials in metal-ion batteries.
Nanoscale, 2025,17, 8999-9020
https://doi.org/10.1039/D5NR00372E

Recent advances in 2D MXene-based heterostructures for gas sensing: mechanisms and applications in environmental and biomedical fields
Schematic representation of MXene based gas sensors: including synthesis, materials design, application and challenges.
Nanoscale, 2025,17, 8975-8998
https://doi.org/10.1039/D4NR04681A
Advances in Perovskite-Based Neuromorphic Computing Devices
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00335K
Single Electron Transistor based Charge Sensors: Fabrication Challenges and Opportunities
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00384A
Immunomodulatory effects of metal nanoparticles: current trends and future prospects
The unique tuneability of various properties of MNPs and immunomodulatory effects are discussed in this review.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR01030F
Solution-synthesized nanostructured materials with high thermoelectric performance
Regulation of grain size/morphology, second phase, and ligand in solution synthesis. Reproduced with permission - see article for full details.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00333D
Material selection, preparation, driving and applications of light-driven micro-nano motor: a review
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05202A
Inspiration of Plant-Related Adhesion for Plant Wearable Sensor Interface Design
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00359H
Design of engineered nanoparticles for biomedical applications by computational modeling
Engineered nanoparticles exhibit superior physicochemical, antibacterial, optical, and sensing properties, rendering them attractive for biomedical applications. Multiscale modeling aids in understanding and optimizing these properties.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05199H
Harnessing chirality in plasmonics: from synthesis to cutting-edge applications
Chiral plasmonic nanostructures have been increasingly explored for asymmetric catalysis, high-sensitivity sensors with selectivity and advanced optical components. This review summarizes their synthesis methods and recent progress in the field.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05229C
Diverse applications of DNA origami as a cross-disciplinary tool
DNA origami provides precise addressable self-assembly templates, demonstrating the tremendous potential of DNA origami technology in promoting interdisciplinary integration and driving technological progress.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04490H
Antimicrobial Peptide Coatings on Implant Surfaces – Current Status and Future Considerations
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D5NR00953G

MXenes in Healthcare: Transformative Applications and Challenges in Medical Diagnostics and Therapeutics
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR04853A
Hydrogel sensing platforms for monitoring contractility in in vitro cardiac models
This review summarizes current methods for monitoring cardiomyocyte contractility and explores recent advances in hydrogel-based platforms for monitoring cell contraction forces. Copyright 2023, Springer Nature; 2019 and 2022, John Wiley and Sons.
Nanoscale, 2025,17, 8436-8452
https://doi.org/10.1039/D4NR04087B
The effects of bandgap and porosity on catalysis and materials characteristics of layered carbon nitrides
Layered nitrides have diverse compositions and pore profiles with wide applications, and are unique but soft and their characterization is challenging. This paper reviews the layered carbon nitrides' syntheses and applications.
Nanoscale, 2025,17, 8415-8435
https://doi.org/10.1039/D4NR05353B
Harnessing carbon electrodes in molecular junctions: progress and challenges in device engineering
Molecular junctions fabricated using different carbon materials and their nanofabrication deposition techniques, showcasing their potential applications.
Nanoscale, 2025,17, 8363-8400
https://doi.org/10.1039/D4NR05242K

Placental targeted drug delivery: a review of recent progress
Key strategies for placental-targeted drug delivery.
Nanoscale, 2025,17, 8316-8335
https://doi.org/10.1039/D4NR05338A

Nanoparticle-based drug delivery systems: opportunities and challenges in the treatment of esophageal squamous cell carcinoma (ESCC)
Nanoparticles boost ESCC treatment efficacy by enhancing drug targeting and overcoming biological barriers, despite biocompatibility and scalability challenges.
Nanoscale, 2025,17, 8270-8288
https://doi.org/10.1039/D4NR05114A

Application of functional coatings in water electrolyzers and fuel cells
This review summarizes recent advances in functional coatings in water electrolyzers and fuel cells, covering both compositional design and mechanism understanding of coating materials.
Nanoscale, 2025,17, 8289-8300
https://doi.org/10.1039/D5NR00137D
Synergistic effect between bacteriophages and nanozymes for hybrid dual recognition of pathogenic bacteria from water, food, and agricultural samples: promising new tools for sensitive and specific biosensing
Bacteriophage–nanozyme as hybrid probes for the detection of pathogenic bacteria.
Nanoscale, 2025,17, 8401-8414
https://doi.org/10.1039/D5NR00146C
Manganese-based nanoenzymes: from catalytic chemistry to design principle and antitumor/antibacterial therapy
This review summarizes the catalytic principles and different structure-based insightful design strategies of Mn-based nanoenzymes, as well as their latest applications and challenges in antitumor and antibacterial applications.
Nanoscale, 2025,17, 8301-8315
https://doi.org/10.1039/D5NR00107B

Optical label-free microscopy characterization of dielectric nanoparticles
Different optical microscopy methods provide different but related single particle information. This tutorial reviews how optical microscopy images can be related to particle properties, including optical theory and strategies for image analysis.
Nanoscale, 2025,17, 8336-8362
https://doi.org/10.1039/D4NR03860F
Nanophotonic structures energized short-wave infrared quantum dot photodetectors and their advancements in imaging and large-scale fabrication techniques
The schematic includes nanophotonic structures energized short-wave infrared quantum dot photodetectors and their advancements in imaging and large-scale fabrication techniques.
Nanoscale, 2025,17, 8239-8269
https://doi.org/10.1039/D4NR03601H
More than a delivery system: the evolving role of lipid-based nanoparticles
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR04508D
Metal cluster-mediated photocatalysis: synthesis, characterization and application
The review of metal cluster materials in photocatalysis including synthetic methodologies, especially AI-assisted synthesis, characterization techniques, and modification strategies and applications.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D5NR00506J
Self-assembled monolayer functionalized metal oxides: a path toward highly selective and low-power consuming gas sensors
The emerging functionalization strategy of self-assembled monolayers (SAMs) offers transformative potential for enhancing the performance of nanostructured metal oxides (MOXs)-based gas sensors.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05307A

Advancing transistor-based point-of-care (POC) biosensors: additive manufacturing technologies and device integration strategies for real-life sensing
Overview of additive manufacturing technologies and potential device integration strategies.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR04441J
Strategies for industrial-grade seawater electrolysis: from electrocatalysts and device design to techno-economic analysis
Nanoscale, 2025, Accepted Manuscript
https://doi.org/10.1039/D4NR05520A
Carbon-based nanostructured materials incorporating carbon dots for supercapacitors: a review
This review summarizes the research progress on the combination of carbon dots and carbon materials in the field of supercapacitors and focuses on discussing the electrochemical properties of materials of different dimensions.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05096G
Advanced flexible self-healing triboelectric nanogenerators for applications in complex environments
Advanced flexible self-healing triboelectric nanogenerators (F-TENGs) achieve reliable energy harvesting in harsh environments, enabling sustainable wearable electronics and sensors through dynamic material innovations.
Nanoscale, 2025,17, 7713-7737
https://doi.org/10.1039/D4NR05170J
Recent progress on transition metal dichalcogenide-based composites for cancer therapy
In this review, we present the recent progress on transition metal dichalcogenide-based composites, including their typical categories, key fabrication strategies, and transformative roles in the field of cancer therapy.
Nanoscale, 2025,17, 7552-7573
https://doi.org/10.1039/D4NR05510A
Advanced disease therapeutics using engineered living drug delivery systems
This review highlights how smart nanomaterials overcome biological barriers by enhancing targeting, reducing off-target effects, and enabling controlled drug release. Created in BioRender. Orash, A. (2025) https://BioRender.com/g97k271
Nanoscale, 2025,17, 7673-7696
https://doi.org/10.1039/D4NR05298F
Recent advances in functional lipid-based nanomedicines as drug carriers for organ-specific delivery
The review highlights lipid-based nanomedicines (LBNs) for organ-specific delivery, focusing on functionalization strategies to improve target specificity, drug stability, therapeutic outcomes, and reduce side effects in clinical applications.
Nanoscale, 2025,17, 7617-7638
https://doi.org/10.1039/D4NR04778H

Recent advances in the fundamentals and in situ characterizations for mechanics in 2D materials
This review involves advances in the mechanics of 2D materials, including measurement methods, sample transfer, materials design, and mechanisms covering the impact of defects and thickness for highly-bendable 2D materials.
Nanoscale, 2025,17, 7574-7599
https://doi.org/10.1039/D4NR05171H
Single photon generation from quantum dots: recent advances, challenges and future directions
Single photon sources (SPS) enable precise quantum communication, secure encryption and quantum computing. Recent research highlights quantum dots as ideal candidates for SPS due to their tunable emission, high stability, brightness and scalability.
Nanoscale, 2025,17, 7651-7672
https://doi.org/10.1039/D5NR00091B
Pd-based chalcogenides for energy conversion electrocatalysis
This review systematically summarizes the recent advances in the use of Pd-based chalcogenides as electrocatalysts for energy conversion reactions.
Nanoscale, 2025,17, 7639-7650
https://doi.org/10.1039/D4NR05230G
Nanophotonic biosensors for COVID-19 detection: advances in mechanisms, methods, and design
The growing societal impact of coronavirus disease 2019 (COVID-19) has underscored the urgent need for innovative strategies to address the ongoing challenges posed by the pandemic.
Nanoscale, 2025,17, 7600-7616
https://doi.org/10.1039/D4NR04423A
Recent advances in MXene nanozyme-based optical and electrochemical biosensors for food safety analysis
Utilization of MXene nanozymes in electrochemical and optical biosensors for food safety.
Nanoscale, 2025,17, 7697-7712
https://doi.org/10.1039/D5NR00066A
Modulation anisotropy of nanomaterials toward monolithic integrated polarization-sensitive photodetectors
This review provides an overview of linear, circular, and full-Stokes photodetectors, discussing how to simplify their design from complex to simple. Images by permission of: RSC 2021, WLY 2023, Optica Publishing Group 2016 and ACS 2020.
Nanoscale, 2025,17, 7533-7551
https://doi.org/10.1039/D4NR05034G

Flexible, wearable mechano-acoustic sensors for body sound monitoring applications
This review highlights recent advances in flexible, wearable mechano-acoustic sensors for body sound measurement, emphasizing their potential for ambulatory health monitoring. Created in BioRender. Dang, T. (2025) https://BioRender.com/l15d184.
Nanoscale, 2025, Advance Article
https://doi.org/10.1039/D4NR05145A
About this collection
In addition to high impact and high quality research across nanoscience & nanotechnology, Nanoscale publishes topical review articles. Reviews will be added to this webpage as soon as possible after publication.