Issue 12, 2024

Bioactive compounds of peanut skin in prevention and adjunctive treatment of chronic non-communicable diseases

Abstract

The global prevalence of cancer continues to increase, so does its mortality. Strategies that can prevent/treat this condition are therefore required, especially low-cost and low-toxicity strategies. Bioactive compounds of plant origin have been presented as a good alternative. In this scenario, due to its abundant polyphenolic content (around 60 to 120 times greater than that of the grain), peanut skin by-products stand out as a sustainable source of food bioactives beneficial to human health. Investigated studies highlighted the importance of peanut skin for human health, its phytochemical composition, bioactivity and the potential for prevention and/or adjuvant therapy in cancer, through the advanced search for articles in the Virtual Health Library (VHL), Science direct and the Mourisco platform of the FioCruz Institute, from 2012 to 2022. Using the keywords, “peanut skin” AND “cancer” AND NOT “allergy”, the words “peanut testa” and “peanut peel” were included replacing “peanut skin”. 18 articles were selected from Plataforma Mourisco, 26 from Science Direct and 26 from VHL. Of these, 7 articles evaluated aspects of cancer prevention and/or treatment. Promising benefits were found in the prevention/treatment of chronic non-communicable diseases in the use of peanut and peanut skin extracts, such as cholesterolemia and glucose control, attenuation of oxidative stress and suppressive action on the proliferation and metabolism of cancer cells.

Graphical abstract: Bioactive compounds of peanut skin in prevention and adjunctive treatment of chronic non-communicable diseases

Article information

Article type
Review Article
Submitted
06 Feb 2024
Accepted
03 May 2024
First published
09 May 2024

Food Funct., 2024,15, 6304-6323

Bioactive compounds of peanut skin in prevention and adjunctive treatment of chronic non-communicable diseases

K. Cordeiro-Massironi, R. A. M. Soares Freitas, I. C. Vieira da Silva Martins, A. C. de Camargo and E. A. F. D. S. Torres, Food Funct., 2024, 15, 6304 DOI: 10.1039/D4FO00647J

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