Issue 2, 2016
From the journal:

Natural Product Reports

Biosynthesis of polyketides by trans-AT polyketide synthases

Eric J. N. Helfricha  and  Jörn Piel*a  

* Corresponding authors

a Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zurich, Vladimir-Prelog-Weg 1-5/10, 8093 Zurich, Switzerland
E-mail: jpiel@ethz.ch
Tel: +41 44 633 07 55

Abstract

Covering 2000 to June 2015

This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of proteins involved in the production of bioactive polyketides. The article includes 609 references and covers the literature from 2009 through June 2015.

Graphical abstract: Biosynthesis of polyketides by trans-AT polyketide synthases

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Article information

DOI
https://doi.org/10.1039/C5NP00125K
Article type
Review Article
Submitted
06 Oct 2015
First published
22 Dec 2015

Nat. Prod. Rep., 2016,33, 231-316

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Biosynthesis of polyketides by trans-AT polyketide synthases

E. J. N. Helfrich and J. Piel, Nat. Prod. Rep., 2016, 33, 231 DOI: 10.1039/C5NP00125K

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