Issue 30, 2024

Heparin binding induced supramolecular chirality into the self-assembly of perylenediimide bolaamphiphile

Abstract

Chirality is one of the hallmarks of biomolecules. Herein, we utilize heparin, a chiral biomolecule and potent drug, to induce chiral organization into the assembly of an achiral molecule. Polyanionic heparin binds with a dicationic perylenediimide derivative to induce supramolecular helical organization in aqueous medium as well as in a highly competitive cell culture medium.

Graphical abstract: Heparin binding induced supramolecular chirality into the self-assembly of perylenediimide bolaamphiphile

Supplementary files

Article information

Article type
Communication
Submitted
19 Apr 2024
Accepted
01 Jul 2024
First published
02 Jul 2024
This article is Open Access
Creative Commons BY-NC license

J. Mater. Chem. B, 2024,12, 7292-7297

Heparin binding induced supramolecular chirality into the self-assembly of perylenediimide bolaamphiphile

P. Sharma, A. Venugopal, C. M. Verdi, M. S. Roger, A. Calò and M. Kumar, J. Mater. Chem. B, 2024, 12, 7292 DOI: 10.1039/D4TB00862F

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