Issue 37, 2023

Fabrication of three-lobed magnetic microrobots for cell transportation

Abstract

Mobile microrobots have the potential to transform medical treatments based on therapeutic delivery. Specifically, microrobots are promising candidates for cell transportation in cell-based therapies. Despite recent progress in cellular manipulation by microrobots, there is a significant need to design and fabricate microrobots to advance the field further. In this work, we present a facile approach to manufacturing three-lobed microrobots by a bench-top procedure. The microrobots are actuated by a harmless magnetic field which makes them biofriendly. Chemically, these microrobots are made of organosilica. The microrobots showed equally good control in both the open-loop and closed-loop settings. The three-lobed microrobots have two modes of motion during the open-loop control experiments. We employed these two modes for single-cell transportation. Our results show that the three-lobed microbots are very promising for cell transportation in a fluid.

Graphical abstract: Fabrication of three-lobed magnetic microrobots for cell transportation

Supplementary files

Article information

Article type
Paper
Submitted
23 Mar 2023
Accepted
06 Jul 2023
First published
06 Jul 2023

J. Mater. Chem. B, 2023,11, 8926-8932

Author version available

Fabrication of three-lobed magnetic microrobots for cell transportation

Z. H. Shah, M. Sokolich, S. Mallick, D. Rivas and S. Das, J. Mater. Chem. B, 2023, 11, 8926 DOI: 10.1039/D3TB00613A

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