A transition-metal-free & diazo-free styrene cyclopropanation†
Ana G.
Herraiz 
ab
and
Marcos G.
Suero
*a
ab
and
Marcos G.
Suero
*a
Abstract
An operationally simple and broadly applicable novel cyclopropanation of styrenes using gem-diiodomethyl carbonyl reagents has been developed. Visible-light triggered the photoinduced generation of iodomethyl carbonyl radicals, able to cyclopropanate a wide array of styrenes with excellent chemoselectivity and functional group tolerance. To highlight the utility of our photocyclopropanation, we demonstrated the late-stage functionalization of biomolecule derivatives.
- This article is part of the themed collection: Editor's choice - Paolo Melchiorre
Please wait while we load your content...
