Issue 39, 2013
From the journal:

Chemical Communications

Curcumin as an amyloid-indicatordye in E. coli†

Oscar A. McCrate,a   Xiaoxue Zhoua  and  Lynette Cegelski*a  

* Corresponding authors

a Department of Chemistry, Stanford University, California 94305, Stanford, USA
E-mail: cegelski@stanford.edu
Fax: +1 650-725-0259
Tel: +1 650-725-3527

Abstract

We have demonstrated that curcumin is an amyloid-specific dye in E. coli. Curcumin binds to curliated whole cells and to isolated curli amyloid fibers. Similar to Congo red, curcumin exhibits a red-shift in absorbance and a significant increase in fluorescence upon binding to isolated curli.

Graphical abstract: Curcumin as an amyloid-indicator dye in E. coli

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Article information

DOI
https://doi.org/10.1039/C2CC37792F
Article type
Communication
Submitted
26 Oct 2012
Accepted
17 Dec 2012
First published
17 Dec 2012

Chem. Commun., 2013,49, 4193-4195

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Curcumin as an amyloid-indicator dye in E. coli

O. A. McCrate, X. Zhou and L. Cegelski, Chem. Commun., 2013, 49, 4193 DOI: 10.1039/C2CC37792F

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