* Corresponding authors

^a Biochemistry, Cellular and Molecular Biology Program, Johns Hopkins University School of Medicine, 316 Hunterian Building, 725 North Wolfe Street, Baltimore, MD 21205, USA
E-mail: netzarroyo@jhmi.edu
Tel: +1 443 287 4798

^b Amgen Scholars Program, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD 21218, USA

^c Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA