Many C-glycosides are found in natural products, drugs and small molecular probes. Herein, we report the synthesis of C-glycosides by the [Au]/[Ag]-catalysed activation of ethynylcyclohexyl glycosyl carbonate donors. This mild, catalytic, fast and high yielding protocol enables the synthesis of a diverse array of C-glycosides that were otherwise challenging to synthesize.
![Graphical abstract: [Au]/[Ag]-catalysed synthesis of non-hydrolysable C-glycosides](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=D4OB01339E&imageInfo.ImageIdentifier.Year=2024)
S. Chakraborty, D. Telang, B. Mishra and S. Hotha, Org. Biomol. Chem., 2024, 22, 9357 DOI: 10.1039/D4OB01339E
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