* Corresponding authors

^a Bio-nanomaterials and Regenerative Medicine Research Division, Zhejiang-California International Nanosystem Institute, Zhejiang University, Hangzhou 310058, China
E-mail: zhrgou@zju.edu.cn
Fax: +86 571-8697 1539
Tel: +86 571-8820 8353

^b Department of Orthopaedic Surgery, Rui’an People's Hospital & the 3rd Hospital Affiliated to Wenzhou Medical University, Rui’an 325200, China

^c Department of Orthopedics, the First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Zhejiang, Hangzhou, China
E-mail: mds@zju.edu.cn

^d Department of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310008, China