* Corresponding authors

^a GBA National Institute for Nanotechnology Innovation, Guangzhou, Guangdong 510700, P.R. China
E-mail: chenchy@nanoctr.cn
Tel: +86 10 82545560

^b CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, P.R. China
E-mail: liuy@nanoctr.cn
Tel: +86 10 82543785

^c Department of Vascular and Endovascular Surgery, Chinese PLA General Hospital, Beijing 100853, P.R. China
E-mail: guoweiplagh@sina.com
Tel: +86 10 66938049

^d Department of Ultrasound, Hospital of Renmin University of China, Beijing 100872, P.R. China

^e Department of Echocardiography, Peking University Third Hospital, Beijing 100191, P.R. China

^f PLA Rocket Force Characteristics Medical Center, Beijing 100888, P.R. China