* Corresponding authors

^a Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, P. R. China
E-mail: chenhw@nju.edu.cn

^b Nanjing Drum Tower Hospital, Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China

^c Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, Ministry of Education, College of Environment, Hohai University, Nanjing, P. R. China
E-mail: guoyong@hhu.edu.cn

^d Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, P. R. China

^e Nanjing Drum Tower Hospital Clinical College of Xuzhou Medical University, Nanjing, P. R. China