* Corresponding authors

^a NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal
E-mail: joao.conde@nms.unl.pt

^b Centre for Toxicogenomics and Human Health (ToxOmics), Genetics, Oncology and Human Toxicology, NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, Portugal

^c Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, NSW 2522, Australia

^d Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia

^e CNC – Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal
E-mail: lino@uc-biotech.pt

^f Faculty of Medicine, University of Coimbra, 3030-789 Coimbra, Portugal