Issue 4, 2020
From the journal:

Chemical Communications

A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels†

Lin Kong, ORCID logo *a   Ze Huang,a   Shuai-Shuai Zhang,a   Jian Song,b   Yu-Yang Zhang,a   Xiang-Yang Bai,a   Jia-Xiang Yang ORCID logo *a  and  Lin Li ORCID logo *c  

* Corresponding authors

a College of Chemistry and Chemical Engineering, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei 230601, P. R. China
E-mail: kong_lin2009@126.com, jxyang@ahu.edu.cn

b College of Physics and Materials Science, Henan Normal University, Xinxiang 453007, China

c Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), National Jiangsu Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, Nanjing 211816, P. R. China
E-mail: iamlli@njtech.edu.cn

Abstract

A novel difluoroboron fluorophore with an electron donor–acceptor conjugated structure was synthesized with 26.5% fluorescence quantum yield, 18 035 GM two-photon absorbing cross-section, and undetectable two-photon fluorescence, resulting in 25% 1O2 quantum yield. The unique optical behavior of CNFBBN enabled one-photon fluorescence imaging and two-photon phototherapy against HeLa cancer cells, irradiated at separate wavelengths.

Graphical abstract: A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels

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Article information

DOI
https://doi.org/10.1039/C9CC07968H
Article type
Communication
Submitted
11 Oct 2019
Accepted
02 Dec 2019
First published
03 Dec 2019

Chem. Commun., 2020,56, 571-574

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A facile strategy to realize a single/double photon excitation-dependent photosensitizer for imaging-guided phototherapy against HeLa cancer cells at separate irradiation channels

L. Kong, Z. Huang, S. Zhang, J. Song, Y. Zhang, X. Bai, J. Yang and L. Li, Chem. Commun., 2020, 56, 571 DOI: 10.1039/C9CC07968H

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