Issue 82, 2018

A ratiometric fluorescent probe for peroxynitrite prepared by de novo synthesis and its application in assessing the mitochondrial oxidative stress status in cells and in vivo

Abstract

A ratiometric fluorescent probe Cy-NEt2 for detecting ONOO is designed and prepared by de novo synthesis, which is a reliable, cheap and flexible route. The probe is applied for monitoring the level of mitochondrial ONOO and assessing the lipopolysaccharide (LPS)-induced mitochondrial oxidative stress status in living cells and in vivo successfully.

Graphical abstract: A ratiometric fluorescent probe for peroxynitrite prepared by de novo synthesis and its application in assessing the mitochondrial oxidative stress status in cells and in vivo

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
11 Sep 2018
Accepted
18 Sep 2018
First published
20 Sep 2018

Chem. Commun., 2018,54, 11590-11593

A ratiometric fluorescent probe for peroxynitrite prepared by de novo synthesis and its application in assessing the mitochondrial oxidative stress status in cells and in vivo

D. Zhou, Y. Li, W. Jiang, Y. Tian, J. Fei and C. Li, Chem. Commun., 2018, 54, 11590 DOI: 10.1039/C8CC07389A

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