* Corresponding authors

^a College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China
E-mail: zhuqingzhang@ucas.ac.cn

^b College of Chemistry and Materials Science, Northwest University, Xi'an, China

^c Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
E-mail: chan@arrhenius.med.toronto.edu

^d Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada