Themed collection Editors’ collection: Photodynamic therapy

Graphene–gold nanocomposite materials combined with (5-fluorouracil, 5-FU) drug show high potent cytotoxicity against MCF-7 cells, can decrease HER-2 gene expression and cause cell cycle arrest.

Folate capped Mn₃O₄ nanoparticles can be used in PDT for specifically destroying folate receptor-overexpressing cancer cells through photo induced free radical damage.

Ag₂S/BSA hybrid nanoparticles were prepared and studied for their ability to inhibit the growth of human lymphoma cells under light irradiation, via inducing the accumulation of intracellular reactive oxidative species to disrupt energy metabolism.

The redox environment modulates photochemical internalization of an entrapped cytotoxic agent. Administration of light depicted by jagged arrow.

In recent years, photodynamic therapy (PDT) studies have gained considerable attention as a non-invasive method used to fight cancer.

A peptide-conjugated zinc(II) phthalocyanine has been prepared which can selectively bind to the epidermal growth factor receptor of cancer cells and induce high cytotoxicity upon illumination.

Photodynamic therapy (PDT) is a promising and effective method for tumor therapy that relies on the reactive oxygen species (ROS) produced by photosensitizers at specific wavelengths to inhibit tumor cells.

Here we show that berberine (BBR) nanoparticles (BBRNPs, ∼300 nm hydrodynamic diameter) is a promising sonosensitizer for cancer sonodynamic therapy (SDT).

Composite nanoparticles of barium titanate and rose Bengal are used to achieve second harmonic generation (SHG) enhanced photodynamic therapy excited by near infrared (NIR) light.

An expedient approach to spot natural photosensitizers was established and with it were – for the first time – photosensitizers in mushrooms identified.

A GSH-responsive nanophotosensitizer based on CoOOH nanosheets was developed for the photodynamic therapy of cancer.

A GO–UCN–SiO₂ hybrid nanocomposite for loading of doxorubicin and its use in in vitro efficiency for killing carcinoma cells.

We successfully synthesized a multifunctional theranostic nanocomposite from upconversion nanoparticles and black phosphorus nanosheets for synergistic photothermal/photodynamic therapies in vitro and dual modal imaging.

Photodynamic therapy (PDT) has attracted much attention as a strategy for tumor therapy.

Mitochondria targeting nanoGUMBOS were successfully fabricated based on self-assembly of IR780 GUMBOS with different counter-anions that show promising anticancer effects.

Antibacterial potentials of four graphene based nanomaterials are tested on a wide range of bacteria.

The photodynamic action mechanism sensitized by a non-charged porphyrin-fullerene C₆₀ dyad and its tetracationic analogue was investigated in solution and in Staphylococcus aureus cells.

TiO_x/DOX nanosheets are synthesized and used as a novel nanodrug system, which introduces new possibilities to improve the efficacy of cancer by the synergistic therapy of chemotherapy and radiotherapy.

A highly efficient synthetic pathway for hypericin as well as its derivatives was achieved under mild and green conditions with high yields.

Inactivation of bacteria and degradation of organic pollutants by engineered nanomaterials (NMs) are very effective approaches in producing safe and clean drinking water.

A series of novel BCC₆₀ composites as multifunctional wound dressings for skin cancer treatment were successfully fabricated using an original dehydration-rehydration method.

Three cationic PSs (M3–M5) exhibited equivalent photodynamic inactivation (PDI) efficacies to MRSA and A. baumannii, while M4 and M5 showed significantly higher PDI to C. albicans, compared to methylene blue, indicating their large potentials on PDI.

Development of photothermal agents for imaging-guided photothermal therapy (PTT) has been of great interest in the field of nanomedicine.

Prepared magnetic chitosan/graphene oxide composite loaded with a novel photosensitizer (MCGO–HNPa) showed excellent PDT activity against HepG-2 cells.

A new class of polyoxoniobate complex has been synthesized and characterized as a novel anticancer agent for photodynamic therapy.

A novel cell permeable, mitochondria localising, diiridium complex has a high emission yield and two heavy atoms to increase scattering of electrons, supporting potential future applications as a dual fluorescence and electron microscopy probe.

A conjugated polyelectrolyte PPET3 functions as an efficient photosensitizer for photodynamic therapy and induces cell apoptosis under white light irradiation.

This work presents a UVA switchable integrin-targeted photodynamic therapy in melanoma, composed of an RGD-modified DLDH conjugated to TiO₂ nanoparticles, with high selectivity towards integrin-expressing cancer cells.

A copper-catalyzed direct C–H arylation or vinylation of BODIPYs at the β-position by iodonium salts has been developed and β-styryl BODIPY 9b has great potential for photodynamic therapy.

Organic nanorods prepared by co-assembly of photosensitizer (BDP-I₂) and chemical anticancer drug, paclitaxel (PTX) were evaluated for chemo-photodynamic therapies.

A novel PDT photosensitizer which features great biomedical properties can be simply prepared.

We demonstrated a new hybrid plasmono-magnetic material for photothermal heating created by grafting Au nanocages onto a surface of magnetic micro-beads.

A novel polypeptide RGDfC-modified selenium nanoparticle was fabricated to selectively deliver HES5-siRNA to tumors for hepatocellular carcinoma therapy.

The F127-GO-DOX supramolecular hydrogel system with sustained drug release characteristic for chemotherapy and photothermal therapy.

The delivery of photosensitizer compounds using biodegradable nanoparticles could improve dosage, controlled release and its bioavailability.