A dual photoredox/palladium-catalyzed three-component reaction of vinyl cyclic carbonates (VCCs), olefins, and Langlois reagent (CF3SO2Na) produced trifluoromethylated allylic alcohols with high stereocontrol and regioselectivity.
A simple and practical visible light-driven photoredox-catalyzed three-component carbotrifluoromethylation of alkenes is revealed for the synthesis of 1,4-bis(trifluoromethylated) compounds.
A base-mediated cascade reaction between alkynyl-1,3-dithianes and α-diazoesters enables the efficient and thermally tunable synthesis of eight-membered sulfur-containing pyrazoles.
A metal-free oxidative decarboxylation reaction of propiolic acids mediated by hypervalent iodine(III) reagents is described.
This review summarizes a decade of advances in the synthesis of alkynyl chalcogen derivatives, emphasizing sustainable catalytic methodologies, mechanistic innovations, and the expanding structural diversity of chalcogenated alkynes.