A polysarcosine-modified NIR-II small-molecule-based polymer (TQF–PSar) was facilely prepared for efficient breast cancer pulmonary metastasis imaging.
In this work we demonstrate the endcapping of a poly(beta-amino ester) of polysarcosine, a widely established PEG-alternative, and show its ability as a non-viral vector for self-amplifying mRNA.
A transformable assembly between vesicle and nanotube was enabled by a bola-type amphiphilic polypeptide with two hydrophilic polysarcosine chains. Their morphology can be changed reversibly as a function of temperature in a time-dependent manner.
Functional polypept(o)ides and ruthenium(II) complexes are combined in photocleavable core cross-linked micelles for colloidal stability. Irradiation-induced cleavage releases the ruthenium pro-drugs and provides spatial resolution to drug delivery.
In situ FTIR monitoring revealed that sarcosine N-carboxyanhydride polymerisations were catalysed using a lysine dendrimer macroinitiator owing to hydrogen bonding interactions between the dendrimer core and monomer.