Nitinol parts prepared by wire arc additive manufacturing were heat-treated to impart excellent superelastic recovery, while exhibiting good corrosion resistance and cytocompatibility, for biomedical applications.
Ketogenic diet-derived faecal microbial transplantation improved sensorimotor gating deficits in an acute NMDA receptor antagonist model of schizophrenia.
The synthesized 2,4-disubstituted thiazole amides showed activity in an MK-801 mouse model. Effective derivatives exhibited significant GPR52 agonist activity, marking them as promising anti-schizophrenia candidates.
A series of N-arylindole GPR52 agonists were developed via linker, head, and tail optimization, showing moderate to good activity and antipsychotic potential. SAR highlights the importance of balanced flexibility and hydroxyl groups.
Katritzky's pioneering studies revealed the multifaceted cycloaddition reactivities of oxidopyridinium betaines. In this review, the follow-up research into oxidopyridinium cycloadditions and their applications are discussed.