Daniel J. Stone, Miguel Macias-Contreras, Shaun M. Crist, Christelle F. T. Bucag, Gwimoon Seo and Lei Zhu
Org. Biomol. Chem., 2023,21, 7419-7436
Abstract
The sequential biochemical (SNAP-tag) and chemical (chelation-assisted copper-catalyzed azide–alkyne cycloaddition) reactions are applied in membrane protein labeling on live cells. The second, chemical step is rapid (within 1 minute) without any ill-effect to the labeled cells.
Joo Hee Choi, Sooin Kim, On-Yu Kang, Seong Yun Choi, Ji Young Hyun, Hyun Soo Lee and Injae Shin
Chem. Soc. Rev., 2024,53, 9446-9489
Abstract
We discuss recent advances in the fluorescent labeling of specific proteins in cells and its applications for studying protein-associated biological processes.
Savina Abraham Pol, Sara Liljenberg, Jack Barr, Gina Simon, Luis Wong-Dilworth, Danielle L. Paterson, Vladimir P. Berishvili, Francesca Bottanelli, Farnusch Kaschani, Markus Kaiser, Mariell Pettersson and Doris Hellerschmied
RSC Chem. Biol., 2024,5, 1232-1247
Abstract
Extending the applications of the SNAP-tag: VHL- and CRBN-recruiting SNAP-PROTACs provide a ready-to-use targeted protein degradation system for SNAP-fusion proteins.
Soham Samanta, Kaitao Lai, Feihu Wu, Yingchao Liu, Songtao Cai, Xusan Yang, Junle Qu and Zhigang Yang
Chem. Soc. Rev., 2023,52, 7197-7261
Abstract
Four important fluorescent building blocks (xanthene, cyanine, oxazine and BODIPY) for super-resolution bioimaging are judiciously assessed.
Dovydas Gabrielaitis, Vilmante Zitkute, Lina Saveikyte, Greta Labutyte, Martynas Skapas, Rolandas Meskys, Vida Casaite, Ausra Sasnauskiene and Urte Neniskyte
Nanoscale Adv., 2023,5, 3705-3716
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Popular Advances
Abstract
Our nanocarriers can deliver enzymatic cargo to cancer cells and are cleared by macrophages in an age dependent manner.