Stanislav A. Paveliev, Andrey Dvoretskiy, Oleg O. Segida, Igor B. Krylov and Alexander O. Terent’ev
Chem. Commun., 2025,61, 14426-14429
Abstract
Electrochemical synthesis of O-imido oximes from azides and N-hydroxyimides via N–O coupling of iminyl and N-oxyl radicals has been discovered.
Alexander S. Budnikov, Igor B. Krylov, Mikhail I. Shevchenko, Lyubov’ L. Sokova, Yan Liu, Bing Yu and Alexander O. Terent'ev
Org. Biomol. Chem., 2024,22, 8755-8763
Abstract
Ring-opening oxyimidation of cyclobutanols and cyclopropanols with the formation of ω-functionalized ketones via radical cross-recombination is reported.
Przemyslaw Frei, Philip J. Kitson, Alexander X. Jones and Leroy Cronin
Digital Discovery, 2023,2, 1326-1333
Abstract
A new modular approach to 3D printed reactionware design is presented, and its effectiveness demonstrated in the synthesis of a number of structurally related, diazirine based, photoaffinity probes.
Marcin Bielinski, Lucy R. Henderson, Yuliana Yosaatmadja, Lonnie P. Swift, Hannah T. Baddock, Matthew J. Bowen, Jürgen Brem, Philip S. Jones, Stuart P. McElroy, Angus Morrison, Michael Speake, Stan van Boeckel, Els van Doornmalen, Jan van Groningen, Helma van den Hurk, Opher Gileadi, Joseph A. Newman, Peter J. McHugh and Christopher J. Schofield
Chem. Sci., 2024,15, 8227-8241
Abstract
SNM1 metallo-β-lactamase fold nucleases (human SNM1A–C) play roles in DNA damage repair and telomere maintenance. Screening and SAR studies lead to selective small molecules validating SNM1A as a cancer target.
Alexander S. Budnikov, Igor B. Krylov, Andrey V. Lastovko, Roman A. Dolotov, Mikhail I. Shevchenko and Alexander O. Terent'ev
Org. Biomol. Chem., 2023,21, 7758-7766
Abstract
The intermolecular oxime radical addition to C
C bonds was discovered employing stable and reactive diacetyliminoxyl as a novel free-radical reagent.