Phyllanthus emblica L. polysaccharides mitigate obesity via modulation of lipid metabolism and gut microbiota in high-fat diet-fed mice

Yi-Hsien Hsu, Sheng-Yi Chen, Jia-De Chen and Gow-Chin Yen

Food Funct., 2025, 16, 5008
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Decoding the mechanistic basis of liver–muscle communication in health and disease

Noha M. Gamil, Habiba A. Elsayed, Esraa T. Salah, Heba A. Mostafa, Riham A. El-Shiekh, Heba R. Ghaiad and Hebatollah E. Eitah

Naunyn-Schmiedeberg's Arch Pharmacol, 2026
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Genistein ameliorates non-alcoholic fatty liver disease in mice by modulating gut microbiota and hepatic macrophage polarization

Shanshan Fang, Hui Han, Rui Wang, Siyu Li, Rui Yang, Shomaila Mehmood and Qiang Jia

Sci Rep, 2025, 15
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GLP-1 receptor agonists: exploration of transformation from metabolic regulation to multi-organ therapy

Bing Gong, Couwen Li, Zhuang’e Shi, FuPing Wang, Ruanxian Dai, Guobing Chen and Heng Su

Front. Pharmacol., 2025, 16
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Butyrate enhances gut dysbiosis by activating the cAMP/PKA/CREB signaling pathway to inhibit the progression of endometrial carcinoma

Muheng Tao, Tingting Wu, Xin Zhou, Fengjie Li, Yingfan Chen, Kaijian Ling and Zhiqing Liang

BMC Microbiol, 2025, 25
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Psyllium-derived, medium-molecular weight arabinoxylan enables modulation of the gut microbiota and metabolites in type 2 diabetic mice

Wei Shen, Rongrong Luo, Lei Yang, Zhiyong Li, Xiancun Hou and Zhao Liu

International Journal of Biological Macromolecules, 2025, 328, 147363
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Regulating the crosstalk between Bifidobacterium and the brain: a potential therapeutic strategy for Alzheimer’s disease

Liting Peng, Zhiming Zhang, Yuan Hu, Huijia Chen, Yingru Tian and Hongyan Ling

Front. Immunol., 2026, 17
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Interaction Between Microbiota and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and New Therapeutic Opportunities

Jingjing Zeng, Zimeng He, Guoqing Wang, Yuxin Ma and Feng Zhang

MedComm, 2025, 6
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Development of a sodium hyaluronate-enriched therapeutic formulation with stevia glycoside and mogroside V for the comprehensive management of diabetes and its complications

Pengyu Lei, Haiyang Yu, Tao Jiang, Jiahui Ma, Jiao Du, Yimeng Fang, Hanbing Wang, Rongbing Chen, Qinsi Yang, Yongwei Cheng, Wei Wu and Da Sun

International Journal of Biological Macromolecules, 2025, 293, 139487
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The Gut-Liver Axis: Molecular Mechanisms and Therapeutic Targeting in Liver Disease

Liang Ma, He Wang, Qiuyu Jin, Zhiwen Sun, Shuang Yu and Yang Zhang

IJGM, 2025, Volume 18, 7531
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Phytochemicals alter foam cell formation and macrophage cholesterol efflux

Zhijun Pan and Wenhua Ling

Metabolism and Diseases, 2026, 1, 100003
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Poria cocos polysaccharides alleviate obesity-related adipose tissue insulin resistance via gut microbiota-derived short-chain fatty acids activation of FGF21/PI3K/AKT signaling

Wenwen Liu, Luzhe Yu, Quan Chen, Chen Zhang, Lei Wang, Nianjun Yu, Daiyin Peng, Jinmei Ou, Weidong Chen, Yue Zhang and Yanyan Wang

Food Research International, 2025, 215, 116671
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Optimal Vegetable Intake for Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD) Prevention: Insights from a South Italian Cohort

Maria Noemy Pastore, Caterina Bonfiglio, Rossella Tatoli, Rossella Donghia, Pasqua Letizia Pesole and Gianluigi Giannelli

Nutrients, 2025, 17, 2477
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Loss of Myostatin Alters Gut Microbiota and Carbohydrate Metabolism to Influence the Gut–Muscle Axis in Cattle

Chao Hai, Hongyu Gong, Yanan Xu, Xuefei Liu, Chunling Bai, Guanghua Su, Lei Yang and Guangpeng Li

Veterinary Sciences, 2025, 12, 560
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Oral Sulforaphane Intervention Protects Against Diabetic Cardiomyopathy in db/db Mice: Focus on Cardiac Lipotoxicity and Substrate Metabolism

Pan Wang, Ziling Wang, Xinyuan Jin, Mengdi Zhang, Mengfan Shen and Dan Li

Antioxidants, 2025, 14, 603
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Multiomics analysis uncovers host-microbiota interactions regulate hybrid vigor traits in geese

Hongyu Ni, Yuwei Yang, Chengwen Wang, Zongdi Li, Wuyang Liu, Yuxin Han, Hao Jiang, Hao Sun, Yumei Li and Yonghong Zhang

Poultry Science, 2025, 104, 105289
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Roles of short-chain fatty acids in metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis

Chun-Ye Zhang, Shuai Liu, Yu-Xiang Sui and Ming Yang

World J Hepatol, 2025, 17
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High-Sucrose Diet-Induced Reprogramming of Plasma Oxylipin Profiles Reflects Dietary Risk for Gut Barrier Dysfunction

Qing-Jin Pan, Hou-Hua Yin, Ya-Nan Liu, Ping Dai, Ying Bai, Xian Fu, Qing Jiang, Yi-Wen Meng, Ai-Zhi Lin, Xue Zhou, Ling Huang, Si-Yi Yin and Jun-Yan Liu

J. Agric. Food Chem., 2025, 73, 22407
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Insulin Resistance Treatment with Balanced Personalized Nutrition to Improve Insulin Sensitivity for Prediabetes Remission and Diabetes Type 2 Reversal with Reduction of Risks for Related Chronic Disease

JNFST, 2024
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Dietary Strategies to Modulate Gut Microbiota in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Federica Perazza, Laura Leoni, Beatrice Selvatici, Francesca Girolami, Alessia Bonalumi, Alice Beretta, Silvia Ferri, Maria Letizia Petroni, Fabio Piscaglia, Federico Ravaioli and Michele Sculati

Nutrients, 2025, 17, 1906
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Therapeutic potential of prebiotics in modulating postprandial GLP-1, GLP-2, and glucose homeostasis in type 2 diabetes mellitus: Targeting gut dysbiosis and insulin resistance

Zainab Irfan, Jitu Halder, Sumon Giri, Ekbal Ali Molla and Sofia Khanam

Diabetes Research and Clinical Practice, 2026, 232, 113102
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Alisol B ameliorated metabolic dysfunction-associated steatotic liver disease via regulating purine metabolism and restoring the gut microbiota disorders

Lin Yiyou, Zhang Congcong, Ren Guilin, Qiu Jiannan, Fu Yilong, Liu Fucai, Liu Qingsheng, Yu Zhiling, Chen Lin and Dou Xiaobing

Phytomedicine, 2025, 145, 156992
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Regulatory Role and Biomarker Potential of Gut Microbiota Metabolites in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease to Hepatocellular Carcinoma

Zongyuan Che, Wei Xue, Xuchen Zhao, Congzhong Hu and Yanzhang Tian

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Sulforaphane ameliorates DSS-induced colitis and secondary liver injury in mice: Proposed mechanism in the SCFAs-FFAR2/3-macrophage polarization axis

Jingyi Ren, Xiaoxin Jiang, Gejun Yu, Wentao Wu, Mengyuan Chen, Yun Zhao, Mengjie Yang, Zuquan Zou and Canxia He

The Journal of Nutritional Biochemistry, 2026, 150, 110239
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The role of gut–islet axis in pancreatic islet function and glucose homeostasis

Qi Chen, Yuanyuan Gao, Fangyu Li and Li Yuan

Diabetes Obesity Metabolism, 2025, 27, 1676
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The Probiotic Parabacteroides johnsonii Ameliorates Metabolic Disorders Through Promoting BCAAs to BSCFAs Conversion

Yimeng Chen, Shujun Jiang, Haolu Wang, Mengzhen Si, Haixia Wu, Xinyi Liang, Shenmeng Yao, Yanliang Zhang, Xiaodong Wen and Jie Yang

Advanced Science, 2025, 12
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Exploring Morchella esculenta polysaccharide extracts: In vitro digestion, fermentation characteristics, and prebiotic potential for modulating gut microbiota and function

Bingshu Liu, Putsawee Tomtong, Suvimol Charoensiddhi and Wanwipa Vongsangnak

International Journal of Biological Macromolecules, 2025, 318, 144910
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Effect of central UAG on metabolic associated fatty liver disease: A possible mechanism involving in GLP-1 neural pathway

Wenxiu Xu, Zixin Du, Jing Wang, Yating Gong, Jiantong Yu, Xueyuying Wang, Xiangrong Sun and Yanling Gong

Peptides, 2025, 191, 171427
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Global research landscape and advancements on the links between the gut microbiome and insulin resistance: hot issues, trends, future directions, and bibliometric analysis

Sa’ed H. Zyoud, Muna Shakhshir, Amani S. Abushanab, Amer Koni, Moyad Shahwan, Ammar A. Jairoun, Banan M. Aiesh and Samah W. Al-Jabi

Gut Pathog, 2025, 17
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Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways

Shi-Long Wang, Si Liang, Si-Yu Li, Jin-Wen Fu, Zi-Yi-Ru Wang, Dong-Qing Zhu and Nan Chen

Front. Microbiol., 2025, 16
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Dietary fiber and metabolic syndrome in NHANES: mediation through inflammation and modifications by population characteristics

Qingqing Zhang, Di Wu, Fengyun Guo, Shengnan Yang, Lijing Bao, Ruiying Zhang and Ping Wang

Nutr Metab (Lond), 2026, 23
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Integrative Multiomics Analysis Reveals the Ameliorative Effects of Astragalus membranaceus Extract on Metabolic Dysfunction-Associated Steatotic Liver Disease

Jiayi An, Yi Li, Zunhan Zhang, Yaru Chang and Guanxiu Xiao

Molecules, 2026, 31, 1120
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Advances in understanding the role of gut microbiota in fat deposition and lipid metabolism

Yi Zhong, Yuhang Lei, Shan Jiang, Dujun Chen, Xinyi Wang, Kai Wang, Tianci Liao, Rongjie Liao, Mailin Gan, Lili Niu, Ye Zhao, Lei Chen, Xiaofeng Zhou, Yan Wang, Li Zhu and Linyuan Shen

J Animal Sci Biotechnol, 2025, 16
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Effect of chestnut (Castanea mollissima) shells flavonoids on pancreatic lipase, steatosis hepatic L-02 cells and gut microbiota

Chenyang Xie, Xuewei Huang, Cunwen Wang and Fang Yang

Food Sci Biotechnol, 2026
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Unveiling the Role of Gut Microbiota and Metabolites in Autoimmune Thyroid Diseases: Emerging Perspectives

Kai Yan, Xin Sun, Chenxi Fan, Xin Wang and Hongsong Yu

IJMS, 2024, 25, 10918
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Molecular mechanisms and clinical applications of gut microbiota-derived bioactive compounds in metabolic dysfunction-associated fatty liver disease

Chengyun Ma, Jing Wang, Xuanli Song, Xue Wang and Shuai Zong

Front. Immunol., 2025, 16
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