Motility-dependent selective transport of active matter in trap arrays: separation methods based on trapping-detrapping and deterministic lateral displacement

Vyacheslav R. Misko, Franco Nori and Wim De Malsche

Nanoscale, 2025, 17, 13434
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High-DNA integrity sperm selection using rheotaxis and boundary following behavior in a microfluidic chip

Soroush Zeaei, Mohammad Zabetian Targhi, Iman Halvaei and Reza Nosrati

Lab Chip, 2023, 23, 2241
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Selection of healthy sperm based on positive rheotaxis using a microfluidic device

Sandhya Sharma, Md. Alamgir Kabir and Waseem Asghar

Analyst, 2022, 147, 1589
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Bio-inspired progressive motile sperm separation using joint rheotaxis and boundary-following behavior

Mohammadjavad Bouloorchi Tabalvandani, Saeed Javadizadeh and Majid Badieirostami

Lab Chip, 2024, 24, 1636
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Lab on a chip devices for fertility: from proof-of-concept to clinical impact

Reza Nosrati

Lab Chip, 2022, 22, 1680
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Selecting active matter according to motility in an acoustofluidic setup: self-propelled particles and sperm cells

Vyacheslav R. Misko, Larysa Baraban, Denys Makarov, Tao Huang, Pierre Gelin, Ileana Mateizel, Koen Wouters, Neelke De Munck, Franco Nori and Wim De Malsche

Soft Matter, 2023, 19, 8635
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A microfluidic method for passive trapping of sperms in microstructures

Binita Nath, Lorenzo Caprini, Claudio Maggi, Alessandra Zizzari, Valentina Arima, Ilenia Viola, Roberto Di Leonardo and Andrea Puglisi

Lab Chip, 2023, 23, 773
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Microfluidic-assisted sperm sorter: a high-throughput sperm selection device

Dhiraj B. Puri, Vadiraj Hemadri, Gautam Biswas and Siddhartha Tripathi

Lab Chip, 2026
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Making and selecting the best embryo in the laboratory

David K. Gardner and Denny Sakkas

Fertility and Sterility, 2023, 120, 457
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Making immotile sperm motile using high-frequency ultrasound

Ali Vafaie, Mohammad Reza Raveshi, Citsabehsan Devendran, Reza Nosrati and Adrian Neild

Sci. Adv., 2024, 10
DOI: 10.1126/sciadv.adk2864

Microfluidics for in vitro fertilization: from science to clinical validation

Virginia Pensabene, Federica Agate, Andreia Santos Miranda and Helen Mary Picton

Human Reproduction Update, 2026, 32, 206
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Sperm Syringe: 3D Sorting Platform for Assisted Reproduction

Farin Yazdan Parast, Moira K. O'Bryan and Reza Nosrati

Adv Materials Technologies, 2022, 7
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Female reproductive tract-on-a-chip for selecting sperm with ultra-low DNA fragmentation index

Jing Dai, Han Shan, Yifan Gu, Mingde Zheng, Li Lou, Pingyuan Xie, Shen Zhang, Zheng Sun, Fei Gong, Guangxiu Lu, Ge Lin and Zeyu Chen

Microsyst Nanoeng, 2026, 12
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基于拉曼光谱技术的精子评筛研究进展

黄祖芳 Huang Zufang, 李玉玲 Li Yuling, 杜生荣 Du Shengrong, 孙艳 Sun Yan, 王佳睿 Wang Jiarui, 张群 Zhang Qun and 陈荣 Chen Rong

Chin. J. Laser, 2023, 50, 1507202
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Advancements in Microfluidic Technologies for Male Infertility

Sahar Shahali, Farzan Akbaridoust, Adrian Neild and Reza Nosrati

Adv Materials Technologies, 2025, 10
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Simple and rapid microfluidic device for processing raw human semen and separation of motile sperm based on their intrinsic behavior and morphology

Mohammad Mahdi Tekiyeh, Mahdi Moghimi Zand, Mansoureh Movahedin, Zahra Azizi and Iman Ramazani Sarbandi

Sci Rep, 2025, 15
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Development of a thermotaxis and rheotaxis microfluidic device for motile spermatozoa sorting

Teng-Kuan Huang, Chung-Hsien Huang, Pei-An Chen, Ching Hung Chen, Farn Lu, Wen-Ju Yang, Jack Yu Jen Huang and Bor-Ran Li

Biosensors and Bioelectronics, 2024, 258, 116353
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Straining Flow Effects on Sperm Flagellar Energetics in Microfluidic Cross‐Slot Traps

Javane Javaherchian, Farin Yazdan Parast, Reza Nosrati, Farzan Akbaridoust and Ivan Marusic

Small, 2025, 21
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Sperm quality metrics were improved by a biomimetic microfluidic selection platform compared to swim-up methods

Steven A. Vasilescu, Lin Ding, Farin Yazdan Parast, Reza Nosrati and Majid Ebrahimi Warkiani

Microsyst Nanoeng, 2023, 9
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Evolution of the basic semen analysis and processing sperm

Jessica N. Schardein, Kiarad Fendereski and James M. Hotaling

Current Opinion in Urology, 2023, 33, 16
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Emerging microfluidic technologies for sperm sorting

Junjie Huang, Hanxu Chen, Ning Li and Yuanjin Zhao

Engineered Regeneration, 2023, 4, 161
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Rheotaxis of sperm cells: mechanism and applications in microfluidic separation

Dhiraj B. Puri, Harshit Wadhwa, Vadiraj Hemadri, Gautam Biswas and Siddhartha Tripathi

Discov. Fluid Mech., 2026, 2
DOI: 10.1007/s44369-026-00005-7

AI and automation in assisted reproduction

Jennifer Lorimer, Robert McLachlan, Deirdre Zander-Fox, Moira K. O’Bryan and Reza Nosrati

Nat Rev Bioeng, 2026
DOI: 10.1038/s44222-026-00454-2

A biomimetic sperm selection device for routine sperm selection

Steven A. Vasilescu, Dale M. Goss, Kathryn H. Gurner, Rebecca L. Kelley, Maria Mazi, Fabrice K. De Bond, Jennifer Lorimer, Fabrizzio Horta, Farin Y. Parast, David K. Gardner, Reza Nosrati and Majid E. Warkiani

Reproductive BioMedicine Online, 2025, 50, 104433
DOI: 10.1016/j.rbmo.2024.104433

Microfluidics: The future of sperm selection in assisted reproduction

Ali Reza Jahangiri, Niloofar Ziarati, Ehsan Dadkhah, Mustafa Numan Bucak, Pegah Rahimizadeh, Abdolhossein Shahverdi, Mohammad Ali Sadighi Gilani and Tohid Rezaei Topraggaleh

Andrology, 2024, 12, 1236
DOI: 10.1111/andr.13578

Integration of Bioengineered Tools in Assisted Reproductive Technologies

Aslı Ak, Edith Coonen, Ron van Golde and Erik Vrij

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202500918

A novel microfluidic device with parallel channels for sperm separation using spermatozoa intrinsic behaviors

Ali Heydari, Mohammad Zabetian Targhi, Iman Halvaei and Reza Nosrati

Sci Rep, 2023, 13
DOI: 10.1038/s41598-023-28315-7