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Design of two-component molecular crystals with defined melting points

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Novel cocrystals of the potent 1,2,4-thiadiazole-based neuroprotector with carboxylic acids: virtual screening, crystal structures and solubility performance

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Enhancing the stability of active pharmaceutical ingredients by the cocrystal strategy

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Pirfenidone–flavonoid cocrystals with reduced solubility and dissolution rate

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A Novel Cocrystal of Daidzein with Piperazine to Optimize the Solubility, Permeability and Bioavailability of Daidzein

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Elucidating the Mechanistic Shortcomings of Acetazolamide Cocrystals in Harnessing the Anticipated Solubility and Permeability Advantages

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Development of ezetimibe eutectic with improved biopharmaceutical and mechanical properties to design an optimized oral solid dosage formulation

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Superior Dissolution Behavior and Bioavailability of Pharmaceutical Cocrystals and Recent Regulatory Issues

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Recent Advances on the Biological Study of Pharmaceutical Cocrystals

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Opportunities and Challenges in Mechanochemical Cocrystallization toward Scaled-Up Pharmaceutical Manufacturing

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Phosphodiesterase Inhibitors of Natural Origin

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Crisaborole-Enthused Glycerosomal Gel for an Augmented Skin Permeation

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An outlook on permeability escalation through cocrystallization for developing pharmaceuticals with improved biopharmaceutical properties

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Development of direct compression Acetazolamide tablet with improved bioavailability in healthy human volunteers enabled by cocrystallization with p-Aminobenzoic acid

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In-line Raman spectroscopy and chemometrics for monitoring cocrystallisation using hot melt extrusion

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Enhanced Dissolution and Diffusion of Ribociclib by Salt Formation with Fluorobenzoic Acid Coformers

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Recent Patents of Pharmaceutical Co-Crystals: Product Development on Anti-Cancer Drugs and Beyond

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Crisaborole loaded nanoemulgel for the mitigation of atopic dermatitis in mice model

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In Situ Monitoring of Competitive Coformer Exchange Reaction by 1H MAS Solid-State NMR

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CFD simulation and experimental study of antisolvent precipitation through impinging jets for synthesis of nanodrug particles

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Mechanistic Insights into Amorphous Solid Dispersions: Bridging Theory and Practice in Drug Delivery

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Pterostilbene–Nicotinamide Cocrystal: A Case Report of Single Cocrystals Grown from Melt Microdroplets

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Solution Stability of Pharmaceutical Cocrystals

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Improving the physicochemical and pharmacokinetic properties of olaparib through cocrystallization strategy

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Inclusion of Hydroxycinnamic Acids in Methylated Cyclodextrins: Host-Guest Interactions and Effects on Guest Thermal Stability

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Particle Size Reduction Techniques of Pharmaceutical Compounds for the Enhancement of Their Dissolution Rate and Bioavailability

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Hydrogen-bonded 2D-3D supramolucular motifs in eight salts combining the antifolate trimethoprim and different carboxylic acids

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From traditional screening to machine learning facilitated development of pharmaceutical cocrystals

Chang Zhang, Li Zhang, Dezhi Yang, Henry H.Y. Tong, Yang Lu and Zhengzheng Zhou

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Crystal Structure, Solubility, and Pharmacokinetic Study on a Hesperetin Cocrystal with Piperine as Coformer

Yanjie Liu, Fan Yang, Xiuhua Zhao, Siying Wang, Qilei Yang and Xiaoxue Zhang

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Tuning Caco-2 permeability by cocrystallization: Insights from molecular dynamics simulation

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Salts of purine alkaloids caffeine and theobromine with 2,6-dihydroxybenzoic acid as coformer: structural, theoretical, thermal and spectroscopic studies

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Improving the Physicochemical and Biopharmaceutical Properties of Active Pharmaceutical Ingredients Derived from Traditional Chinese Medicine through Cocrystal Engineering

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Pharmaceutics, 2021, 13, 2160
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Studies of "drug-drug" multi-component crystals of trimethoprim and probenecid

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Formation of Ciprofloxacin–Isonicotinic Acid Cocrystal Using Mechanochemical Synthesis Routes—An Investigation into Critical Process Parameters

Maryam Karimi-Jafari, Ahmad Ziaee, Emmet O’Reilly, Denise Croker and Gavin Walker

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Multi-modal feature fusion graph neural networks for intelligent classification of pharmaceutical solid forms: Cocrystals, salts, and physical mixtures

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Development of sulfamethoxazole-succinimide cocrystal by mechanochemical cocrystallization – An insight into spectroscopic, electronic, chemical conformation and physicochemical properties

Parag Roy, Noopur Pandey, Nimmy Kumari, Ritika Baidya, Y. Sheena Mary, Y. Shyma Mary and Animesh Ghosh

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Extending the Range of Nitrofurantoin Solid Forms: Effect of Molecular and Crystal Structure on Formation Thermodynamics and Physicochemical Properties

Artem O. Surov, Alexander P. Voronin, Ksenia V. Drozd, Tatyana V. Volkova, Nikita Vasilev, Dmitriy Batov, Andrei V. Churakov and German L. Perlovich

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A Metformin-Ferulic Acid Salt with Improved Biopharmaceutical Parameters

José Venâncio Chaves Júnior, Alejandro Pedro Ayala, Daniel de Lima Pontes, Fábio Santos de Souza and Cícero Flávio Soares Aragão

Journal of Pharmaceutical Sciences, 2023, 112, 3120
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Solid-state and particle size control of pharmaceutical cocrystals using atomization-based techniques

Aaron O'Sullivan, Barry Long, Vivek Verma, Kevin M. Ryan and Luis Padrela

International Journal of Pharmaceutics, 2022, 621, 121798
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