Antibacterial polylysine-containing hydrogels for hemostatic and wound healing applications: preparation methods, current advances and future perspectives

Sara Pourshahrestani, Ehsan Zeimaran and Mh Busra Fauzi

Biomater. Sci., 2024, 12, 3293
DOI: 10.1039/D3BM01792C

Hydrogels with protective effects against cellular oxidative stress via enzymatic crosslinking of feruloylated arabinoxylan from corn fibre

Secil Yilmaz-Turan, Kun Jiang, Patricia Lopez-Sanchez, Amparo Jiménez-Quero, Thomas Crouzier, Tomás S. Plivelic and Francisco Vilaplana

Green Chem., 2022, 24, 9114
DOI: 10.1039/D2GC03331C

Engineering a platelet-rich plasma-based multifunctional injectable hydrogel with photothermal, antibacterial, and antioxidant properties for skin regeneration

Vajihe Alinezhad, Kimia Esmaeilzadeh, Hadi Bagheri, Habib Zeighami, Ali Kalantari-Hesari, Rahim Jafari, Pooyan Makvandi, Yi Xu, Hamidreza Mohammadi, Mohammad-Ali Shahbazi and Aziz Maleki

Biomater. Sci., 2023, 11, 5872
DOI: 10.1039/D3BM00881A

Facile fabrication of chitin/ZnO composite hydrogels for infected wound healing

Hongli Zhang, Xu Zhang, Qi Cao, Shuangquan Wu, Xiao-Qiang Wang, Na Peng, Danlin Zeng, Jinfeng Liao and Huan Xu

Biomater. Sci., 2022, 10, 5888
DOI: 10.1039/D2BM00340F

Applications and interventions of polymers and nanomaterials in alveolar bone regeneration and tooth dentistry

Prashish Sharma, Sushmita Saurav, Zeba Tabassum, Bhawana Sood, Anil Kumar, Tabarak Malik, Anand Mohan and Madhuri Girdhar

RSC Adv., 2024, 14, 36226
DOI: 10.1039/D4RA06092J

The design principle of natural polysaccharide hydrogels for promoting wound healing: a prospective review

Ruyue Wang, Maohu Chen, Yonghua Chu, Wensheng Pan and Feng Chen

J. Mater. Chem. B, 2025, 13, 4722
DOI: 10.1039/D4TB02576H

A multifunctional 3D dressing unit based on the core–shell hydrogel microfiber for diabetic foot wound healing

Qiwei Huang, Tingbin Wu, Lihuan Wang, Jichang Zhu, Yongshi Guo, Xi Yu, Longfei Fan, John H. Xin and Hui Yu

Biomater. Sci., 2022, 10, 2568
DOI: 10.1039/D2BM00029F

Advances in cellulose-based hydrogels: tunable swelling dynamics and their versatile real-time applications

Md. Mahamudul Hasan Rumon

RSC Adv., 2025, 15, 11688
DOI: 10.1039/D5RA00521C

Bioactive hydrogels based on polysaccharides and peptides for soft tissue wound management

Lihuang Wu, Yiyan He, Hongli Mao and Zhongwei Gu

J. Mater. Chem. B, 2022, 10, 7148
DOI: 10.1039/D2TB00591C

A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing

Wencheng Liang, Qiaohui Lu, Fan Yu, Junyong Zhang, Chuang Xiao, Xiaoming Dou, Yan Zhou, Xiumei Mo, Jun Li and Meidong Lang

Biomater. Sci., 2021, 9, 7124
DOI: 10.1039/D1BM01185E

Alginate/chitosan-based hydrogel loaded with gene vectors to deliver polydeoxyribonucleotide for effective wound healing

Xiaodong Jing, Yanzhen Sun, Yang Liu, Xiaoli Ma and Hao Hu

Biomater. Sci., 2021, 9, 5533
DOI: 10.1039/D1BM00911G

A review of recent advances in metal ion hydrogels: mechanism, properties and their biological applications

Xin Zhang, Yuanhan Tang, Puying Wang, Yanyan Wang, Tingting Wu, Tao Li, Shuo Huang, Jie Zhang, Haili Wang, Songmei Ma, Linlin Wang and Wenlong Xu

New J. Chem., 2022, 46, 13838
DOI: 10.1039/D2NJ02843C

Supramolecular hydrogels for wound repair and hemostasis

Shaowen Zhuo, Yongping Liang, Zhengying Wu, Xin Zhao, Yong Han and Baolin Guo

Mater. Horiz., 2024, 11, 37
DOI: 10.1039/D3MH01403G

Multifunctional antibacterial hydrogels for chronic wound management

Yungang Hu, Lu Yu, Qiang Dai, Xiaohua Hu and Yuming Shen

Biomater. Sci., 2024, 12, 2460
DOI: 10.1039/D4BM00155A

Marine polysaccharides: green and recyclable resources as wound dressings

Xiaodong Jing, Yanzhen Sun, Xiaoli Ma and Hao Hu

Mater. Chem. Front., 2021, 5, 5595
DOI: 10.1039/D1QM00561H

Recent trends on burn wound care: hydrogel dressings and scaffolds

Yingxia Yao, Andi Zhang, Congshan Yuan, Xiguang Chen and Ya Liu

Biomater. Sci., 2021, 9, 4523
DOI: 10.1039/D1BM00411E

Development of chitosan-based curative films containing β-d-glucan obtained from Rhodotorula mucilaginosa yeast and containing bromelain extract carried in nanoparticles and liposomes

Sara Lima Alves, Thaise Cruz Lopes, Patrícia Carvalho de Almeida Chagas, Márcio Campos Oliveira, Marcus Vinicius Santos da Silva, Fernanda Vidigal Duarte Souza and Sandra Aparecida de Assis

New J. Chem., 2024, 48, 17052
DOI: 10.1039/D4NJ01623H

Wound healing strategies based on nanoparticles incorporated in hydrogel wound patches

Paulami Dam, Merve Celik, Merve Ustun, Sayantan Saha, Chirantan Saha, Elif Ayse Kacar, Senanur Kugu, Elif Naz Karagulle, Savaş Tasoglu, Fatih Buyukserin, Rittick Mondal, Priya Roy, Maria L. R. Macedo, Octávio L. Franco, Marlon H. Cardoso, Sevde Altuntas and Amit Kumar Mandal

RSC Adv., 2023, 13, 21345
DOI: 10.1039/D3RA03477A

Natural polyphenolic antibacterial bio-adhesives for infected wound healing

Hengjie Zhang, Yuqi Feng, Tianyou Wang, Jianhua Zhang, Yuxian Song, Jing Zhang, Yiwen Li, Dingzi Zhou and Zhipeng Gu

Biomater. Sci., 2024, 12, 2282
DOI: 10.1039/D3BM02122J

Hemostatic nanotechnologies for external and internal hemorrhage management

Liying Wang, Xinru You, Chunlei Dai, Tong Tong and Jun Wu

Biomater. Sci., 2020, 8, 4396
DOI: 10.1039/D0BM00781A

Harnessing biomolecules for bioinspired dental biomaterials

Nicholas G. Fischer, Eliseu A. Münchow, Candan Tamerler, Marco C. Bottino and Conrado Aparicio

J. Mater. Chem. B, 2020, 8, 8713
DOI: 10.1039/D0TB01456G

Recent advances on polymeric hydrogels as wound dressings

Zheng Pan, Huijun Ye and Decheng Wu

APL Bioengineering, 2021, 5
DOI: 10.1063/5.0038364

Structure and Dynamics of Water in Polysaccharide (Alginate) Solutions and Gels Explained by the Core–Shell Model

Avery A. Agles and Ian C. Bourg

Biomacromolecules, 2024, 25, 6403
DOI: 10.1021/acs.biomac.4c00447

Genipin crosslinked quaternary ammonium chitosan hydrogels for wound dressings

Ling Wang, Xiaoyue Ding, Jingyu Li, Man Li, Peng Ding, Wei Guo, Qiaoyun Wu, Yanfang Sun, Guohua Jiang, Oseweuba Valentine Okoro, Mahta Mirzaei, Amin Shavandi, Lihong Fan and Lei Nie

Biomed. Mater., 2024, 19, 045042
DOI: 10.1088/1748-605X/ad525f

Exopolysaccharides Producing Bacteria: A Review

Alexander I. Netrusov, Elena V. Liyaskina, Irina V. Kurgaeva, Alexandra U. Liyaskina, Guang Yang and Viktor V. Revin

Microorganisms, 2023, 11, 1541
DOI: 10.3390/microorganisms11061541

Hybrid Nanoparticle–Hydrogel Systems for Drug Delivery Depots and Other Biomedical Applications

Wonmin Choi and Daniel S. Kohane

ACS Nano, 2024, 18, 22780
DOI: 10.1021/acsnano.4c06888

Dynamic covalent bonding based polysaccharide hydrogels and their applications in wound dressings: A review

Haibing Gao, Zhen Wang, Ting Lin, Guolong Zhang, Xiao Han and Cui Cheng

Colloids and Surfaces B: Biointerfaces, 2025, 254, 114878
DOI: 10.1016/j.colsurfb.2025.114878

Artificial Kidney Capsule Packed with Mesenchymal Stem Cell-Laden Hydrogel for the Treatment of Rhabdomyolysis-Induced Acute Kidney Injury

Zhangning Fu, Yanji Chu, Xiaodong Geng, Yingchao Ma, Kun Chi, Chengcheng Song, Shenglong Liao, Quan Hong, Di Wu and Yapei Wang

ACS Biomater. Sci. Eng., 2022, 8, 1726
DOI: 10.1021/acsbiomaterials.1c01595

Research progress and challenges of composite wound dressings containing plant extracts

Linlin Ding, Leiliang He, Yifu Wang, Xueying Zhao, Hui Ma, Yuanhao Luo, Fangxia Guan and Yamin Xiong

Cellulose, 2023, 30, 11297
DOI: 10.1007/s10570-023-05602-0

Research progress on MXenes in polysaccharide-based hemostasis and wound healing: A review

Bichong Luo, Xiaofei Bai, Yujie Hou, Jing Guo, Zhongshuang Liu, Yongbin Duan and Zhengguo Wu

International Journal of Biological Macromolecules, 2025, 303, 140613
DOI: 10.1016/j.ijbiomac.2025.140613

Multifunctional moxifloxacin and essential oil loaded sodium alginate/thiolated karaya gum hydrogel dressings for improved wound healing

Fizza Abdul Razzaq, Syed Haroon Khalid, Ikram Ullah Khan and Sajid Asghar

International Journal of Biological Macromolecules, 2025, 312, 144234
DOI: 10.1016/j.ijbiomac.2025.144234

Single-Component Self-Healing Antibacterial Anti-Inflammatory Intracellular-Antioxidative Poly(itaconic acid-pluronic) Hydrogel for Rapid Repair of MRSA-Impaired Wound

Junping Ma, Ting Li, Meng Luo and Bo Lei

ACS Appl. Mater. Interfaces, 2023, 15, 33413
DOI: 10.1021/acsami.3c05383

A dual network cross-linked hydrogel with multifunctional Bletilla striata polysaccharide/gelatin/tea polyphenol for wound healing promotion

Hongyu Ma, Yongbu Axi, Yuanhui Lu, Chunguang Dai, Shengting Huang, Zilin Kong, Rezhemu Jimo, Heran Li, Gongzheng Chen, Ping Li, Liang Zhang, Yan Qu, Xuhua Qin, Rui Zeng and Kaijun Gou

International Journal of Biological Macromolecules, 2024, 265, 130780
DOI: 10.1016/j.ijbiomac.2024.130780

Antimicrobial Peptides and Macromolecules for Combating Microbial Infections: From Agents to Interfaces

Luofeng Yu, Kunpeng Li, Jing Zhang, Haoyu Jin, Atif Saleem, Qing Song, Qingyan Jia and Peng Li

ACS Appl. Bio Mater., 2022, 5, 366
DOI: 10.1021/acsabm.1c01132

Robust, anti-freezing and conductive bonding of chitosan-based double-network hydrogels for stable-performance flexible electronic

Yanyu Yang, Manhua Zhou, Junbo Peng, Xing Wang, Yang Liu, Wanjie Wang and Decheng Wu

Carbohydrate Polymers, 2022, 276, 118753
DOI: 10.1016/j.carbpol.2021.118753

CARBOXYLATED NANOCELLULOSE OBTAINED THROUGH ULTRASONICATION USING AN ALTERNATIVE ACID MIXTURE SOLVENT

JÉSSICA MICHEL DA SILVA, LUIZA RIBEIRO SANTANA , RAFAEL BELTRAME , MÁRIO LÚCIO MOREIRA , NEFTALI LENIN VILLARREAL CARREÑO and RAFAEL DE AVILA DELUCIS

Cellulose Chem. Technol., 2024, 58, 215
DOI: 10.35812/CelluloseChemTechnol.2024.58.21

Advancements in characterization and preclinical applications of hyaluronic acid-based biomaterials for wound healing: A review

Marjan Talebi, Rouzbeh Almasi Ghale, Roghayeh Mokhtari Asl and Fatemeh Tabandeh

Carbohydrate Polymer Technologies and Applications, 2025, 9, 100706
DOI: 10.1016/j.carpta.2025.100706

Electrospun Polysaccharidic Textiles for Biomedical Applications

Daria Poshina and Issei Otsuka

Textiles, 2021, 1, 152
DOI: 10.3390/textiles1020007

Hydrogel Membranes from Chitosan-Fish Gelatin-Glycerol for Biomedical Applications: Chondroitin Sulfate Incorporation Effect in Membrane Properties

Andreas Karydis-Messinis, Dimitrios Moschovas, Maria Markou, Kyriaki Tsirka, Christina Gioti, Eleni Bagli, Carol Murphy, Aris E. Giannakas, Alkis Paipetis, Michael A. Karakassides, Apostolos Avgeropoulos, Constantinos E. Salmas and Nikolaos E. Zafeiropoulos

Gels, 2023, 9, 844
DOI: 10.3390/gels9110844

Innovative applications of multidimensional engineered hydrogels in wound healing

Min Hu, Qiaoyan Zhang and Luping Qin

Journal of Advanced Research, 2025
DOI: 10.1016/j.jare.2025.08.006

Synergistic effects of arginine and tannic acid on chitosan matrices: An approach for hemostatic sponge development

Rizos Evangelos Bikiaris, Nikolaos Iosif Matschek, Ioanna Koumentakou, Argyri Niti and George Z. Kyzas

International Journal of Biological Macromolecules, 2025, 318, 145105
DOI: 10.1016/j.ijbiomac.2025.145105

Magnetic nanostructure and biomolecule synergistically promoted Suaeda-inspired self-healing hydrogel composite for seawater evaporation

Xizhi Jiang, Nina Yan, Min Wang, Min Feng, Qingbao Guan and Lei Xu

Science of The Total Environment, 2022, 830, 154545
DOI: 10.1016/j.scitotenv.2022.154545

Mussel‐Inspired Adhesive, Antibacterial, and Stretchable Composite Hydrogel for Wound Dressing

Ying Chen, Xiaokun Fan, Jiawei Lu, Xin Liu, Jin Chen and Yi Chen

Macromolecular Bioscience, 2023, 23
DOI: 10.1002/mabi.202200370

A Study on the Clinical Progress of Polysaccharide Hydrogel Bone Promoting Repair

皓瑞邓

ACM, 2023, 13, 4759
DOI: 10.12677/ACM.2023.133681

Rational design of antimicrobial peptide conjugated graphene-silver nanoparticle loaded chitosan wound dressing

Priyadarshani Choudhary, Baskaran Ramalingam and Sujoy K. Das

International Journal of Biological Macromolecules, 2023, 246, 125347
DOI: 10.1016/j.ijbiomac.2023.125347

Promotion of chronic wound healing by plant-derived active ingredients and research progress and potential of plant polysaccharide hydrogels

Ru Yan, Yanhong Wang, Weinan Li and Jialin Sun

Chinese Herbal Medicines, 2025, 17, 70
DOI: 10.1016/j.chmed.2024.11.005

3D Bioprinted Scaffolds for Tissue Repair and Regeneration

Na Liu, Xiaopei Zhang, Qingxia Guo, Tong Wu and Yuanfei Wang

Front. Mater., 2022, 9
DOI: 10.3389/fmats.2022.925321

Multifunctional nanofibrous patches composed of nanocellulose and lysozyme nanofibers for cutaneous wound healing

Nuno H.C.S. Silva, Patrícia Garrido-Pascual, Catarina Moreirinha, Adelaide Almeida, Teodoro Palomares, Ana Alonso-Varona, Carla Vilela and Carmen S.R. Freire

International Journal of Biological Macromolecules, 2020, 165, 1198
DOI: 10.1016/j.ijbiomac.2020.09.249

Advanced radiation-crosslinked CM-chitosan/gelatin hydrogel for diabetic ulcer treatment with reducing application frequency

Hongwei Li, Xuefei Chen, Youbin Fan, Tianquan Wang, Xin Chen and Ling Xu

Diabetes Research and Clinical Practice, 2025, 223, 112153
DOI: 10.1016/j.diabres.2025.112153

Electrical stimulation induced by a piezo-driven triboelectric nanogenerator and electroactive hydrogel composite, accelerate wound repair

Anjana Sharma, Vineeta Panwar, Bidya Mondal, Dixit Prasher, Milan Kumar Bera, Jijo Thomas, Ajay Kumar, Navpreet Kamboj, Dipankar Mandal and Deepa Ghosh

Nano Energy, 2022, 99, 107419
DOI: 10.1016/j.nanoen.2022.107419

The effects of degassing, neutralization, and dewatering on the CMC-g-poly (acrylic acid-co-methacrylic acid) hydrogel

Mina Pourkhatoun, Maryam Kalantari, Ata Kamyabi and Ali Moradi

Polymers from Renewable Resources, 2023, 14, 195
DOI: 10.1177/20412479231182698

Polysaccharides, proteins and DNA based stimulus responsive hydrogels promoting wound healing and repair: A review

Yumo She, Peng Wu, Wenyu Wan, He Liu, Ruonan Liu, Tingting Wang, Mengyao Wang, Lufan Shen, Yuanyuan Yang, Xingyong Huang, Xiaoyue Zhang, Ye Tian and Kai Zhang

International Journal of Biological Macromolecules, 2025, 304, 140961
DOI: 10.1016/j.ijbiomac.2025.140961

Effective Strategies for Developing Potent, Broad-Spectrum Antibacterial and Wound Healing Promotion from Short-Chain Antimicrobial Peptides

Fengyuan Gao, Adeel Ahmed, Hailin Cong, Bing Yu and Youqing Shen

ACS Appl. Mater. Interfaces, 2023, 15, 32136
DOI: 10.1021/acsami.3c03069

Living-loaded hydrogel: Strategies for loading living, interactions between loaded living and hydrogel, and applications

Ran Zhang, Xueyao Liu, Yanzhe Gou, Wenli Zhang, Benke Cui, Ronglian Xing, Yanan Huang, Guoning Nan, Chunguang Ren and Zhihong Tang

European Polymer Journal, 2024, 213, 113130
DOI: 10.1016/j.eurpolymj.2024.113130

Pro‐Regenerative Glycopeptide Hydrogel Activates Type 2 Immune Response for Wound Healing via Macrophage‐T Cell Crosstalk

Jingrong Wang, Xiang Liu, Yaping Wang, Yushan Zhang, Rui Gao, Yu Gao, Pengxu Kong, Yini Huangfu, Chuangnian Zhang, Zujian Feng, Pingsheng Huang, Pengxiang Yang and Weiwei Wang

Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202307711

Combination of lyophilized adipose-derived stem cell concentrated conditioned medium and polysaccharide hydrogel in the inhibition of hypertrophic scarring

Chaoyu Zhang, Ting Wang, Li Zhang, Penghong Chen, Shijie Tang, Aizhen Chen, Ming Li, Guohao Peng, Hangqi Gao, Haiyan Weng, Haoruo Zhang, Shirong Li, Jinghua Chen, Liangwan Chen and Xiaosong Chen

Stem Cell Res Ther, 2021, 12
DOI: 10.1186/s13287-020-02061-3

Classification, processing, and applications of bioink and 3D bioprinting: A detailed review

Sania Raees, Faheem Ullah, Fatima Javed, Hazizan Md. Akil, Muhammad Jadoon Khan, Muhammad Safdar, Israf Ud Din, Mshari A. Alotaibi, Abdulrahman I. Alharthi, M. Afroz Bakht, Akil Ahmad and Amal A. Nassar

International Journal of Biological Macromolecules, 2023, 232, 123476
DOI: 10.1016/j.ijbiomac.2023.123476

Gastric acid-response chitosan/alginate/tilapia collagen peptide composite hydrogel: Protection effects on alcohol-induced gastric mucosal injury

Sitong Lu, Songzhi Kong, Ye Wang, Zhang Hu, Lingyu Zhang and Mingneng Liao

Carbohydrate Polymers, 2022, 277, 118816
DOI: 10.1016/j.carbpol.2021.118816

Living cell‐laden hydrogels: Unleashing the future of responsive biohybrid systems

Xuejia Hu, Bing Lei, Sen‐Sen Li, Lu‐Jian Chen and Quan Li

Responsive Materials, 2023, 1
DOI: 10.1002/rpm.20230009

Renewable Electroconductive Hydrogels for Accelerated Diabetic Wound Healing and Motion Monitoring

Xiao Qian Hu, Jia Zhi Zhu, Zhaokun Hao, Letian Tang, Jian Sun, Wan Ru Sun, Jiaxiang Hu, Ping Yu Wang, Nicola Paccione Basmadji, José Luis Pedraz, Claudia Vairo, Eusebio Gainza Lafuente, Murugan Ramalingam, Shuyang Xie and Ranran Wang

Biomacromolecules, 2024, 25, 3566
DOI: 10.1021/acs.biomac.4c00205

Synthesis and characterization of curcumin-loaded pH/reduction dual-responsive folic acid modified carboxymethyl cellulose-based microcapsules for targeted drug delivery

Qingye Meng, Shuangling Zhong, Shihao He, Yan Gao and Xuejun Cui

Journal of Industrial and Engineering Chemistry, 2022, 105, 251
DOI: 10.1016/j.jiec.2021.09.021

The Influence of Cell Cycle Regulation on Chemotherapy

Ying Sun, Yang Liu, Xiaoli Ma and Hao Hu

IJMS, 2021, 22, 6923
DOI: 10.3390/ijms22136923

A novel pullulan oxidation approach to preparing a shape memory sponge with rapid reaction capability for massive hemorrhage

Weishi Zheng, Zheng Zhang, Yuyu Li, Lujie Wang, Feiya Fu, Hongyan Diao and Xiangdong Liu

Chemical Engineering Journal, 2022, 447, 137482
DOI: 10.1016/j.cej.2022.137482

State-of-the-Art Insights and Potential Applications of Cellulose-Based Hydrogels in Food Packaging: Advances towards Sustainable Trends

Ajit Kumar Singh, Pontree Itkor and Youn Suk Lee

Gels, 2023, 9, 433
DOI: 10.3390/gels9060433

Fabrication and characterization of an antibacterial chitosan-coated allantoin-loaded NaCMC/SA skin scaffold for wound healing applications

Mohammad Haki, Amir Shamloo, Sara-Sadat Eslami, Fatemeh Mir-Mohammad-Sadeghi, Sasan Maleki and Arman Hajizadeh

International Journal of Biological Macromolecules, 2023, 253, 127051
DOI: 10.1016/j.ijbiomac.2023.127051

Bioinspired Multifunctional Cellulose Nanofibril-Based In Situ Liquid Wound Dressing for Multiple Synergistic Therapy of the Postoperative Infected Wound

Chao Zhao, Rimei Chen, Zhiping Chen, Qin Lu, Hongxiang Zhu, Qing Bu, Jiali Yin and Hui He

ACS Appl. Mater. Interfaces, 2021, 13, 51578
DOI: 10.1021/acsami.1c18221

Enhanced Mechanical Properties of PVA Hydrogel by Low-Temperature Segment Self-Assembly vs. Freeze–Thaw Cycles

Fei Wu, Jianfeng Gao, Yang Xiang and Jianming Yang

Polymers, 2023, 15, 3782
DOI: 10.3390/polym15183782

An NIR-responsive hydrogel loaded with polydeoxyribonucleotide nano-vectors for enhanced chronic wound healing

Yanzhen Sun, Yao Li, Xiaokang Ding, Pan Xu, Xiaodong Jing, Hailin Cong, Hao Hu, Bing Yu and Fu-Jian Xu

Biomaterials, 2025, 314, 122789
DOI: 10.1016/j.biomaterials.2024.122789

Characterization of a New Silk Sericin-Based Hydrogel for Water Retention in Soil

Natalia Jaramillo-Quiceno, Catalina Álvarez-López, Gustavo Adolfo Hincapié-Llanos, Carlos A. Hincapié and Marisol Osorio

Polymers, 2023, 15, 2763
DOI: 10.3390/polym15132763

Metallic‐Polyphenolic Nanoparticles Reinforced Cationic Guar Gum Hydrogel for Effectively Treating Burn Wound

Yangjing Bai, Shiying Lang, Yangrui Du, Qinsheng Hu, Xinyun Li and Gongyan Liu

Macromolecular Bioscience, 2024, 24
DOI: 10.1002/mabi.202300396

Pullulan hydrogel-immobilized bacterial cellulose membranes with dual-release of vitamin C and E for wound dressing applications

Deniz Atila, Ayten Karataş, Dilek Keskin and Ayşen Tezcaner

International Journal of Biological Macromolecules, 2022, 218, 760
DOI: 10.1016/j.ijbiomac.2022.07.160

Combinational System of Lipid-Based Nanocarriers and Biodegradable Polymers for Wound Healing: An Updated Review

Bahareh Farasati Far, Mohammad Reza Naimi-Jamal, Meysam Sedaghat, Alireza Hoseini, Negar Mohammadi and Mahdi Bodaghi

JFB, 2023, 14, 115
DOI: 10.3390/jfb14020115

In-situ wound healing by SDF-1-mimic peptide-loaded click crosslinked hyaluronic acid scaffold

Young Hun Kim, Shina Kim, Hyun Jin Ju, Min Ji Han, Yongdoo Park, Eunha Kim, Hak Soo Choi, Sangdun Choi and Moon Suk Kim

Journal of Controlled Release, 2023, 364, 420
DOI: 10.1016/j.jconrel.2023.10.047

A modular ROS-responsive platform co-delivered by 10-hydroxycamptothecin and dexamethasone for cancer treatment

Qingye Meng, Hao Hu, Xiaodong Jing, Ying Sun, Liping Zhou, Yaowei Zhu, Bing Yu, Hailin Cong and Youqing Shen

Journal of Controlled Release, 2021, 340, 102
DOI: 10.1016/j.jconrel.2021.10.027

Insight into Factors Influencing Wound Healing Using Phosphorylated Cellulose-Filled-Chitosan Nanocomposite Films

Marta Kędzierska, Sara Blilid, Katarzyna Miłowska, Joanna Kołodziejczyk-Czepas, Nadia Katir, Mohammed Lahcini, Abdelkrim El Kadib and Maria Bryszewska

IJMS, 2021, 22, 11386
DOI: 10.3390/ijms222111386

Natural polysaccharide-based hydrogels for hemostasis and wound healing: A review

Peng Wang, Yuji Pu and Bin He

Precision Medicine and Engineering, 2025, 2, 100016
DOI: 10.1016/j.preme.2025.100016

Novel Copper Nanoparticles Intercalated Polyurethane Heparin/Poly-L-Lysine Chelates Coated Stents: Viability Study for Coronary Vascular Cells and Aneurysms Treatments

Ji Ma, Teng-Fei Li and Hui-Feng Yuan

j biomed nanotechnol, 2021, 17, 216
DOI: 10.1166/jbn.2021.3023

A review of self-healing hydrogels for bone repair and regeneration: Materials, mechanisms, and applications

Bo Li, Chenchen Li, Ziyi Yan, Xiaoling Yang, Wenqian Xiao, Dawei Zhang, Zhongning Liu and Xiaoling Liao

International Journal of Biological Macromolecules, 2025, 287, 138323
DOI: 10.1016/j.ijbiomac.2024.138323

Combination of natural polyanions and polycations based on interfacial complexation for multi-functionalization of wound dressings

Shuyang Li, Liya Wang, Jue Zhang, Zijun Zhao, Weifeng Yu, Zhi Tan, Po Gao and Xingtao Chen

Front. Bioeng. Biotechnol., 2022, 10
DOI: 10.3389/fbioe.2022.1006584

Incorporation of Bioglass Improved the Mechanical Stability and Bioactivity of Alginate/Carboxymethyl Chitosan Hydrogel Wound Dressing

Xin Wu and Haiyan Li

ACS Appl. Bio Mater., 2021, 4, 1677
DOI: 10.1021/acsabm.0c01477

Synergic fabrication of titanium dioxide incorporation into heparin-polyvinyl alcohol nanocomposite: enhanced in vitro antibacterial activity and care of in vivo burn injury

Shougen Li, Jia Zeng, Dongfang Yin, Peiqiang Liao, Siqing Ding, Ping Mao and Ying Liu

Mater. Res. Express, 2021, 8, 085012
DOI: 10.1088/2053-1591/abe1fb

Anti‐inflammatory hydrogel dressings and skin wound healing

Can Huang, Lanlan Dong, Baohua Zhao, Yifei Lu, Shurun Huang, Zhiqiang Yuan, Gaoxing Luo, Yong Xu and Wei Qian

Clinical & Translational Med, 2022, 12
DOI: 10.1002/ctm2.1094

Innovations in Drug Delivery for Chronic Wound Healing

Erfan Rezvani Ghomi , Mohamadreza Shakiba, Ali Saedi Ardahaei , Mahsa Akbari Kenari, Mehdi Faraji, Shahla Ataei , Parisa Kohansal, Iman Jafari, Majid Abdouss and Seeram Ramakrishna

CPD, 2022, 28, 340
DOI: 10.2174/1381612827666210714102304

Combined treatment strategy of hydrogel dressing and physiotherapy for rapid wound healing

Xiaofei Xie, Chenhui Zhu, Jing Zhao, Yanru Fan, Huan Lei and Daidi Fan

Advances in Colloid and Interface Science, 2025, 341, 103477
DOI: 10.1016/j.cis.2025.103477

Magnesium Oxide‐Assisted Dual‐Cross‐Linking Bio‐Multifunctional Hydrogels for Wound Repair during Full‐Thickness Skin Injuries

Xiaoduo Tang, Xiaomeng Wang, Yihan Sun, Liang Zhao, Daowei Li, Junhu Zhang, Hongchen Sun and Bai Yang

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202105718

Hemp Protein Isolate-Based Natural Thermal-Reversible Hydrogel as a Novel Wound Dressing Material

Baochen Fang, Zhicheng Peng, Bingcan Chen and Jiajia Rao

ACS Appl. Mater. Interfaces, 2024, 16, 51916
DOI: 10.1021/acsami.4c05854

Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy

Yanzhen Sun, Xiaodong Jing, Xiaoli Ma, Yinglong Feng and Hao Hu

IJMS, 2020, 21, 9159
DOI: 10.3390/ijms21239159

Hemostatic and antimicrobial properties of chitosan-based wound healing dressings: A review

Jieyu Su, Chengsheng Liu, Ao Sun, Jingquan Yan, Feng Sang, Ying Xin, Yan Zhao, Shiyun Wang and Qifeng Dang

International Journal of Biological Macromolecules, 2025, 306, 141570
DOI: 10.1016/j.ijbiomac.2025.141570

Polysaccharide based transdermal patches for chronic wound healing: Recent advances and clinical perspective

Suhela Tyeb, Vivek Verma and Nitesh Kumar

Carbohydrate Polymers, 2023, 316, 121038
DOI: 10.1016/j.carbpol.2023.121038

Using bacterial cellulose to bridge covalent and physical crosslinks in hydrogels for fabricating multimodal sensors

Chenguang Jiang, Yuchen Chao, Wenyuan Xie and Defeng Wu

International Journal of Biological Macromolecules, 2024, 263, 130178
DOI: 10.1016/j.ijbiomac.2024.130178

Microenvironment responsive nanocomposite hydrogel with NIR photothermal therapy, vascularization and anti-inflammation for diabetic infected wound healing

Shuangli Zhu, Bangjiao Zhao, Maocai Li, Hao Wang, Jiayi Zhu, Qingtao Li, Huichang Gao, Qi Feng and Xiaodong Cao

Bioactive Materials, 2023, 26, 306
DOI: 10.1016/j.bioactmat.2023.03.005

Mimosa‐Inspired High‐Sensitive and Multi‐Responsive Starch Actuators

Hao Hu, Mingzhe Nie, Massimiliano Galluzzi, Xuefeng Yu and Xuemin Du

Adv Funct Materials, 2023, 33
DOI: 10.1002/adfm.202304634

Polysaccharide-Based Nanogels to Overcome Mucus, Skin, Cornea, and Blood-Brain Barriers: A Review

Ju Wang, Marco Viola, Claudia Migliorini, Luca Paoletti, Silvia Arpicco, Chiara Di Meo and Pietro Matricardi

Pharmaceutics, 2023, 15, 2508
DOI: 10.3390/pharmaceutics15102508

A tissue-adhesive, mechanically enhanced, natural Aloe Vera-based injectable hydrogel for wound healing: Macrophage mediation and collagen proliferation

Xueting Wang, Jing Yang, Qimeng Zhao, Xianchang Xie, Fuling Deng, Ziyi Wang, Kunpeng Jiang, Xiaoming Li, Hu Liu, Zhenhao Shi, Xu Zhu, Lei Chen and Dalun Lv

International Journal of Biological Macromolecules, 2024, 283, 137452
DOI: 10.1016/j.ijbiomac.2024.137452

Interpenetrating polymer network based hydrogel: A smart approach for corroborating wound healing of various capacity

Manoj Kumar Sarangi, Sasmita Padhi, L. D. Patel, Goutam Rath, Sitansu Sekhar Nanda and Dong Kee Yi

J of Applied Polymer Sci, 2023, 140
DOI: 10.1002/app.54312

Tailorable biosensors for real-time monitoring of stress distribution in soft biomaterials and living tissues

Fenghou Yuan, Huitang Qi, Binghui Song, Yuntian Cui, Junsheng Zhang, Huan Liu, Bo Liu, Hai Lei and Tian Liu

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-56422-8

Enzyme Catalyzed Hydrogel as Versatile Bioadhesive for Tissue Wound Hemostasis, Bonding, and Continuous Repair

Juan Zhou, Yanzhe Wu, Xihe Zhang, Jiahui Lai, Yuanli Li, Jian Xing, Liping Teng and Jinghua Chen

Biomacromolecules, 2021, 22, 1346
DOI: 10.1021/acs.biomac.0c01329

Exploiting synergistic effect of CO/NO gases for soft tissue transplantation using a hydrogel patch

Xiaoduo Tang, Jingyan Ren, Xin Wei, Tao Wang, Haiqiu Li, Yihan Sun, Yang Liu, Mingli Chi, Shoujun Zhu, Laijin Lu, Junhu Zhang and Bai Yang

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-37959-y

Bifunctional lignocellulose nanofiber hydrogel possessing intriguing pH-responsiveness and self-healing capability towards wound healing applications

Wenwen Li, Gege Cheng, Shuangju Wang, Yan Jiang, Xiuyu Liu and Qin Huang

International Journal of Biological Macromolecules, 2024, 260, 129398
DOI: 10.1016/j.ijbiomac.2024.129398

Multifunctional Cu2Se/F127 Hydrogel with SOD‐Like Enzyme Activity for Efficient Wound Healing

Jia He, Wei Zhang, Yuyu Cui, Liang Cheng, Xu‐Lin Chen and Xianwen Wang

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202303599

Drug-free and non-crosslinked chitosan/hyaluronic acid hybrid hydrogel for synergistic healing of infected diabetic wounds

Yao Lin, Jingchen Xu, Yuanhao Dong, Yue Wang, Chenhao Yu, Yuanhong Li, Chaoliang Zhang, Qianming Chen, Song Chen and Qiang Peng

Carbohydrate Polymers, 2023, 314, 120962
DOI: 10.1016/j.carbpol.2023.120962

Electrical Stimulation Mediated by Piezo-Driven Triboelectric Nanogenerator and Electroactive Hydrogel Encourage Wound Repair

Deepa Ghosh, Anjana Sharma, Vineeta Panwar, Bidya Mondal, Dixit Prasher, Milan Kumar Bera, Jijo Thomas, Ajay Kumar, Navpreet Kamboj and Dipankar Mandal

SSRN Journal, 2022
DOI: 10.2139/ssrn.4065624

Natural okra-based hydrogel for chronic diabetic wound healing

Peikun Xin, Shuyan Han, Jun Huang, Conglai Zhou, Jiayuan Zhang, Xinru You and Jun Wu

Chinese Chemical Letters, 2023, 34, 108125
DOI: 10.1016/j.cclet.2022.108125

Enhancing soil water retention and plant growth with thermal crosslinked silk sericin-based hydrogel

Natalia Jaramillo-Quiceno, Ana Sofía Duque Carmona, Juliana Serna Serna, Dora M. Carmona, Mabel Torres-Taborda, Gustavo Adolfo Hincapié-Llanos, Juan Felipe Santa Marín and Catalina Álvarez-López

Journal of Environmental Chemical Engineering, 2024, 12, 112260
DOI: 10.1016/j.jece.2024.112260

Calycosin-7-glucoside-Loaded Hydrogel Promotes Wound Healing in Gestational Diabetes Mellitus

Jicong Lu, Yingying Guo, Zhaoyuan Yang, Mengxia Xie, Shuangyu Zhang, Keji Li, Jingjing Yang, Shanhui Xue, Da Xu, Kanglu Yan and Yuehua Liu

ACS Appl. Bio Mater., 2025, 8, 4186
DOI: 10.1021/acsabm.5c00290

In situ formed tissue-adhesive carboxymethyl chitosan hydrogels through photoclick chemistry for wound healing

Jun Wang, Fei Qi, Huiying Feng, Anqi Xu, Dao-Qiang Lu, Junru Liang, Ziwen Zhang, Jie Li, Dahai Liu, Bin Zhang and Yanling Hu

European Polymer Journal, 2024, 203, 112680
DOI: 10.1016/j.eurpolymj.2023.112680

Controlling size and stabilization of silver nanoparticles for use in optimized chitosan-dialdehyde xylan wound dressings

Gong Chen, Tingting Han, Zhouyang Xiang and Tao Song

Cellulose, 2022, 29, 5833
DOI: 10.1007/s10570-022-04635-1

Bioactive Injectable Hydrogel Dressings for Bacteria-Infected Diabetic Wound Healing: A “Pull–Push” Approach

Kunbao Zhang, Chao Yang, Chuanxu Cheng, Chengxin Shi, Madi Sun, Hanze Hu, Tongfei Shi, Xuenian Chen, Xuan He, Xiao Zheng, Mingqiang Li and Dan Shao

ACS Appl. Mater. Interfaces, 2022, 14, 26404
DOI: 10.1021/acsami.2c04300

Click-Chemistry Approach toward Antibacterial and Degradable Hybrid Hydrogels Based on Octa-Betaine Ester Polyhedral Oligomeric Silsesquioxane

Jin Han, Qinyue Chen, Yupeng Shen, Zhixiong Liu, Xiaoyu Hao, Mingqiang Zhong, Zhengping Zhao and Michael R. Bockstaller

Biomacromolecules, 2020, 21, 3512
DOI: 10.1021/acs.biomac.0c00530

Novel chitosan-ulvan hydrogel reinforcement by cellulose nanocrystals with epidermal growth factor for enhanced wound healing: In vitro and in vivo analysis

Kazharskaia Mariia, Muhammad Arif, Jie Shi, Fulai Song, Zhe Chi and Chenguang Liu

International Journal of Biological Macromolecules, 2021, 183, 435
DOI: 10.1016/j.ijbiomac.2021.04.156

Bio-based poly (γ-glutamic acid)-gelatin double-network hydrogel with high strength for wound healing

Chunyan Dou, Zheng Li, Ying Luo, Jixian Gong, Qiujin Li, Jianfei Zhang, Qingsong Zhang and Changsheng Qiao

International Journal of Biological Macromolecules, 2022, 202, 438
DOI: 10.1016/j.ijbiomac.2022.01.057

Evaluation of drug release efficiency and antibacterial property of a pH-responsive dextran-based silver nanocomposite hydrogel

Amos Luanda, M. Manohar, Rompicherla Narayana Charyulu and Vishalakshi Badalamoole

International Journal of Biological Macromolecules, 2024, 268, 131783
DOI: 10.1016/j.ijbiomac.2024.131783

Designing protein-polysaccharides based bioactive copolymeric network by supra-molecular interactions for sustained drug delivery

Nistha Thakur and Baljit Singh

Supramolecular Materials, 2023, 2, 100048
DOI: 10.1016/j.supmat.2023.100048

Mucus Mimic Hydrogel Coating for Lubricous, Antibiofouling, and Anti-Inflammatory Urinary Catheters

Sijia Zheng, Ying Liu, Jun Yao, Ruiying Zhu, Xing Yu and Zhihai Cao

ACS Appl. Mater. Interfaces, 2024, 16, 46177
DOI: 10.1021/acsami.4c13051

Near-Infrared Responsive Nanocomposite Hydrogel Dressing with Anti-Inflammation and Pro-Angiogenesis for Wound Healing

Wen Luo, Zhenzhen Li, Junjie Che, Xinyao Li, Huali Zhang, Jinxiu Tian, Chunyang Wang, GuiYing Li and Lin Jin

ACS Appl. Mater. Interfaces, 2024, 16, 34720
DOI: 10.1021/acsami.4c06193

Dual‐Cross‐Linked Chitosan‐Based Antibacterial Hydrogels with Tough and Adhesive Properties for Wound Dressing

Jingjing Du, Yutong Zhang, Yilin Huang, Qiao Zhang, Wenzhi Wang, Maolin Yu, Lijian Xu and Jianxiong Xu

Macromol. Rapid Commun., 2023, 44
DOI: 10.1002/marc.202300325

Hybrids of Polysaccharides and Inorganic Nanoparticles: From Morphological Design to Diverse Biomedical Applications

Nana Zhao, Zhuolong Jiao, Linghui Chen, Zhiwen Liu, Xiaoyi Zhao and Fu-Jian Xu

Acc. Mater. Res., 2023, 4, 1068
DOI: 10.1021/accountsmr.3c00172

Rapid innervation and physiological epidermal regeneration by bioengineered dermis implanted in mouse

Claudia Mazio, Isabella Mavaro, Antonio Palladino, Costantino Casale, Francesco Urciuolo, Andrea Banfi, Livia D'Angelo, Paolo A. Netti, Paolo de Girolamo, Giorgia Imparato and Chiara Attanasio

Materials Today Bio, 2024, 25, 100949
DOI: 10.1016/j.mtbio.2024.100949

Bactericidal Hemostatic Sponge: A Point of Care Solution to Combat Traumatic Injury

Rajib Dey, Riya Mukherjee, Sudip Mukherjee and Jayanta Haldar

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202404176

Stimuli-Responsive Self-Healing Ionic Gels: A Promising Approach for Dermal and Tissue Engineering Applications

Deepanjan Datta, Viola Colaco, Sony Priyanka Bandi, Namdev Dhas, Leela Sai Lokesh Janardhanam, Sudarshan Singh and Lalitkumar K. Vora

ACS Biomater. Sci. Eng., 2025, 11, 1338
DOI: 10.1021/acsbiomaterials.4c02264

A review of polysaccharide-based hydrogels: From structural modification to biomedical applications

Ran Zhang, Xueyao Liu, Wenli Zhang, Benke Cui, Yongduo Du, Yanan Huang, Wenjun Li, Qun Liu, Chunguang Ren and Zhihong Tang

International Journal of Biological Macromolecules, 2025, 310, 143519
DOI: 10.1016/j.ijbiomac.2025.143519

Stimulus-responsive starch-based nanocapsules for targeted delivery and antibacterial applications

Qingye Meng, Liping Zhou, Shuangling Zhong, Jingfei Wang, Jia Wang, Yan Gao and Xuejun Cui

International Journal of Biological Macromolecules, 2023, 241, 124664
DOI: 10.1016/j.ijbiomac.2023.124664

Fucoidan- and carrageenan-based biosynthetic poly(vinyl alcohol) hydrogels for controlled permeation

Md. Lutful Amin, Damia Mawad, Socrates Dokos, Pramod Koshy, Penny Jo Martens and Charles C. Sorrell

Materials Science and Engineering: C, 2021, 121, 111821
DOI: 10.1016/j.msec.2020.111821

Drug Delivery Strategies and Biomedical Significance of Hydrogels: Translational Considerations

Neha Raina, Rakesh Pahwa, Jaydeep Bhattacharya, Alok K. Paul, Veeranoot Nissapatorn, Maria de Lourdes Pereira, Sonia M. R. Oliveira, Karma G. Dolma, Mohammed Rahmatullah, Polrat Wilairatana and Madhu Gupta

Pharmaceutics, 2022, 14, 574
DOI: 10.3390/pharmaceutics14030574

Mussel-inspired blue-light-activated cellulose-based adhesive hydrogel with fast gelation, rapid haemostasis and antibacterial property for wound healing

Shengchang Lu, Xiaohui Zhang, Zuwu Tang, He Xiao, Min Zhang, Kai Liu, Lihui Chen, Liulian Huang, Yonghao Ni and Hui Wu

Chemical Engineering Journal, 2021, 417, 129329
DOI: 10.1016/j.cej.2021.129329

A review of recent advances in drug loading, mathematical modeling and applications of hydrogel drug delivery systems

Xiaohan Hu, Chenyun Zhang, Yingshuo Xiong, Songmei Ma, Changmei Sun and Wenlong Xu

J Mater Sci, 2024, 59, 15077
DOI: 10.1007/s10853-024-10103-x

Advanced Foam Dressing of Modified Graphene Nanoparticles Loaded in Bacterial Cellulose/Calcium Alginate Matrix

Thamyres Freire da Silva, Jacilane Ximenes Mesquita, Erika Patricia Chagas Gomes Luz, Alexandre Lopes Andrade, Henry Kobs, Edson Holanda Teixeira, Antônio Gomes de Souza Filho, Andreia Fonseca de Faria, Adriano Lincoln Albuquerque Mattos, Fábia Karine Andrade and Rodrigo Silveira Vieira

ACS Omega, 2025, 10, 28969
DOI: 10.1021/acsomega.5c00609

Self‐Healing Supramolecular Hydrogels with Antibacterial Abilities for Wound Healing

Zhiwu Hong, Lei Wu, Zherui Zhang, Jinpeng Zhang, Huajian Ren, Gefei Wang, Xiuwen Wu, Guosheng Gu, Jianan Ren and Huan Wang

Journal of Healthcare Engineering, 2023, 2023
DOI: 10.1155/2023/7109766

Stimuli-Responsive Polysaccharide Hydrogels and Their Composites for Wound Healing Applications

Maria Psarrou, Anna Mitraki, Maria Vamvakaki and Chrysoula Kokotidou

Polymers, 2023, 15, 986
DOI: 10.3390/polym15040986

Polysaccharide-based hydrogel promotes skin wound repair and research progress on its repair mechanism

Shuai Zhang, Hongyuan Liu, Wei Li, Xinglong Liu, Lina Ma, Ting Zhao, Qiteng Ding, Chuanbo Ding and Wencong Liu

International Journal of Biological Macromolecules, 2023, 248, 125949
DOI: 10.1016/j.ijbiomac.2023.125949

Current research progress of smart hydrogels in wound healing – a review

Yingying Sui, Junjie Yu, Fangang Meng and Wenxia Sui

International Journal of Polymeric Materials and Polymeric Biomaterials, 2025, 1
DOI: 10.1080/00914037.2025.2495144

The Intracellular and Extracellular Microenvironment of Tumor Site: The Trigger of Stimuli‐Responsive Drug Delivery Systems

Xiaodong Jing, Hao Hu, Yanzhen Sun, Bing Yu, Hailin Cong and Youqing Shen

Small Methods, 2022, 6
DOI: 10.1002/smtd.202101437

3D bioprinting of a cell-laden antibacterial polysaccharide hydrogel composite

Hadi Rastin, Mahnaz Ramezanpour, Kamrul Hassan, Arash Mazinani, Tran Thanh Tung, Sarah Vreugde and Dusan Losic

Carbohydrate Polymers, 2021, 264, 117989
DOI: 10.1016/j.carbpol.2021.117989

Intelligent polymeric hydrogen sulfide delivery systems for therapeutic applications

Fan Rong, Tengjiao Wang, Qian Zhou, Haowei Peng, Jingtian Yang, Quli Fan and Peng Li

Bioactive Materials, 2023, 19, 198
DOI: 10.1016/j.bioactmat.2022.03.043

An Injectable Antibiotic Hydrogel that Scavenges Proinflammatory Factors for the Treatment of Severe Abdominal Trauma

Chao Yang, Jianati Dawulieti, Kunbao Zhang, Chuanxu Cheng, Yawei Zhao, Hanze Hu, Mingqiang Li, Ming Zhang, Li Chen, Kam W. Leong and Dan Shao

Adv Funct Materials, 2022, 32
DOI: 10.1002/adfm.202111698

Research Progress on Emerging Polysaccharide Materials Applied in Tissue Engineering

Chunyu Su, Yutong Chen, Shujing Tian, Chunxiu Lu and Qizhuang Lv

Polymers, 2022, 14, 3268
DOI: 10.3390/polym14163268

Covalently Crosslinked Hydrogels via Step‐Growth Reactions: Crosslinking Chemistries, Polymers, and Clinical Impact

Yongsheng Gao, Kevin Peng and Samir Mitragotri

Advanced Materials, 2021, 33
DOI: 10.1002/adma.202006362

Oligochitosan and oxidized nucleoside-based bioderived hydrogels for wound healing

Rafael Itzhakov, Noy Eretz-Kdosha, Eldad Silberstein, Topaz Alfer, Raanan Gvirtz, Elazar Fallik, Navit Ogen-Shtern, Guy Cohen and Elena Poverenov

Carbohydrate Polymers, 2023, 314, 120947
DOI: 10.1016/j.carbpol.2023.120947

Hydrogels and hydrogel-based drug delivery systems for promoting refractory wound healing: Applications and prospects

Xuran Lin, Xinge Zhang, Yuechen Wang, Weiyu Chen, Zhikang Zhu and Shoujie Wang

International Journal of Biological Macromolecules, 2025, 285, 138098
DOI: 10.1016/j.ijbiomac.2024.138098

Bio‐based polymers containing traditional medicinal fillers for wound healing applications – An evaluation of neoteric development and future perspectives

Hema S, Vaani V. Unni, Gayathri, Niranjan B, Smitha Chandran and Sreedha Sambhudevan

Biotechnology Journal, 2023, 18
DOI: 10.1002/biot.202300006

Development of chitosan-based hydrogels for healthcare: A review

Mo Xiao

International Journal of Biological Macromolecules, 2023, 244, 125333
DOI: 10.1016/j.ijbiomac.2023.125333

Recent advancements of nitric oxide-releasing hydrogels for wound dressing applications

Nurhasni Hasan, Cao Jiafu, Apon Zaenal Mustopa, Achmad Himawan, Rifqiyah Nur Umami, Muneeb Ullah, Nasrul Wathoni and Jin-Wook Yoo

J. Pharm. Investig., 2023, 53, 781
DOI: 10.1007/s40005-023-00636-9

Advancements in Regenerative Hydrogels in Skin Wound Treatment: A Comprehensive Review

Gabriel Olteanu, Sorinel Marius Neacșu, Florin Alexandru Joița, Adina Magdalena Musuc, Elena Carmen Lupu, Corina-Bianca Ioniță-Mîndrican, Dumitru Lupuliasa and Magdalena Mititelu

IJMS, 2024, 25, 3849
DOI: 10.3390/ijms25073849

Effect of Starch Oxidation Degree on the Properties of Hydrogels from Dialdehyde Starch and Polyvinyl Alcohol

Jahel Desire Carrera, Daniela Alejandra Viteri Narváez, Marco Leon and José Francisco Alvarez-Barreto

Adv. sci. technol. eng. syst. j., 2020, 5, 1372
DOI: 10.25046/aj0506165

A Dual‐Cross‐Linked Hydrogel Patch for Promoting Diabetic Wound Healing

Jing Liu, Moyuan Qu, Canran Wang, Yumeng Xue, Hui Huang, Qianming Chen, Wujin Sun, Xingwu Zhou, Guihua Xu and Xing Jiang

Small, 2022, 18
DOI: 10.1002/smll.202106172

Prevention of chemotherapy-induced premature ovarian insufficiency in mice by scaffold-based local delivery of human embryonic stem cell-derived mesenchymal progenitor cells

Eun-Young Shin, Da-Seul Kim, Min Ji Lee, Ah Reum Lee, Sung Han Shim, Seung Woon Baek, Dong Keun Han and Dong Ryul Lee

Stem Cell Res Ther, 2021, 12
DOI: 10.1186/s13287-021-02479-3

Multifunctional Nanoclay‐Based Hemostatic Materials for Wound Healing: A Review

Ya Tan, Qian Yang, Meng Zheng, Muhammad Tariq Sarwar and Huaming Yang

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202302700

Convergence of tissue engineering and sustainable development goals

Naresh Kasoju and Anagha Sunilkumar

Biotechnol Sustain Mater, 2024, 1
DOI: 10.1186/s44316-024-00021-y

pH factors in chronic wound and pH-responsive polysaccharide-based hydrogel dressings

Itishree Jogamaya Das and Trishna Bal

International Journal of Biological Macromolecules, 2024, 279, 135118
DOI: 10.1016/j.ijbiomac.2024.135118

Hemocompatible, biocompatible and antifouling Acylated dextran-g-polytetrahydrofuran graft copolymer with silver nanoparticles: Synthesis, characterization and properties

Cong-Lei Zhao, Jin-Rui Deng, Yu-Zhuang Gao and Yi-Xian Wu

Materials Science and Engineering: C, 2021, 123, 111998
DOI: 10.1016/j.msec.2021.111998

Polysaccharide-modified magnetic drug nanocarriers: Structures and applications in cancer chemotherapy

Ali Pourjavadi, Sakineh Alipour and Mohadeseh Doroudian

Journal of Drug Delivery Science and Technology, 2024, 91, 105140
DOI: 10.1016/j.jddst.2023.105140

Collagen/gelatin and polysaccharide complexes enhance gastric retention and mucoadhesive properties

Khurshid Ahmad, Yuqian Meng, Chaozhong Fan, Aiman Salah Ud Din, Qiannan Jia, Azqa Ashraf, Yanying Zhang and Hu Hou

International Journal of Biological Macromolecules, 2024, 266, 131034
DOI: 10.1016/j.ijbiomac.2024.131034

Functional Hydrogels for Treatment of Chronic Wounds

Ilayda Firlar, Mine Altunbek, Colleen McCarthy, Murugan Ramalingam and Gulden Camci-Unal

Gels, 2022, 8, 127
DOI: 10.3390/gels8020127

High strength chitosan hydrogels prepared from NaOH/urea aqueous solutions: the role of thermal gelling

Zhengbo Lu, Lei Zou, Xiaoman Zhou, Di Huang and Yongjun Zhang

Carbohydrate Polymers, 2022, 297, 120054
DOI: 10.1016/j.carbpol.2022.120054

Recent advances in polysaccharides based biomaterials for drug delivery and tissue engineering applications

Ankur Sood, Aastha Gupta and Garima Agrawal

Carbohydrate Polymer Technologies and Applications, 2021, 2, 100067
DOI: 10.1016/j.carpta.2021.100067

Protein/polysaccharide-based hydrogels loaded probiotic-mediated therapeutic systems: A review

Bing-De Zheng, Lei Gan, Li-Yuan Tian and Guan-Hong Chen

International Journal of Biological Macromolecules, 2023, 253, 126841
DOI: 10.1016/j.ijbiomac.2023.126841

Multifunctional and theranostic hydrogels for wound healing acceleration: An emphasis on diabetic-related chronic wounds

Pooya M. Tehrany, Parham Rahmanian, Aryan Rezaee, Golnaz Ranjbarpazuki, Farima Sohrabi Fard, Yasaman Asadollah salmanpour, Mohammad Arad Zandieh, Ali Ranjbarpazuki, Sajedeh Asghari, Nazanin Javani, Noushin Nabavi, Amir Reza Aref, Mehrdad Hashemi, Mohsen Rashidi, Afshin Taheriazam, Alireza Motahari and Kiavash Hushmandi

Environmental Research, 2023, 238, 117087
DOI: 10.1016/j.envres.2023.117087

Emerging horizons and prospects of polysaccharide-constructed gels in the realm of wound healing

Shen-Han Wu, Lekshmi Rethi, Wen-Yu Pan, Hieu Trung Nguyen and Andrew E.-Y. Chuang

Colloids and Surfaces B: Biointerfaces, 2024, 235, 113759
DOI: 10.1016/j.colsurfb.2024.113759

Layer-by-layer coating of carboxymethyl chitosan-gelatin-alginate on cotton gauze for hemostasis and wound healing

Weishi Zheng, Chuntao Chen, Xujun Zhang, Xiaodong Wen, Yuanxiang Xiao, Lin Li, Qingbo Xu, Feiya Fu, Hongyan Diao and Xiangdong Liu

Surface and Coatings Technology, 2021, 406, 126644
DOI: 10.1016/j.surfcoat.2020.126644

In Situ Preparation of Mechanically Enhanced Hydrogel via Dispersion Polymerization in Aqueous Solution

Honggui Chen, Xiang Zhang, Ziyu Lin, Rui Zhang, Bingran Yu, Yang Li and Fu‐Jian Xu

Macromol. Rapid Commun., 2021, 42
DOI: 10.1002/marc.202100028

Efficacy of biomaterials in burn treatment: Comparative study of collagen-derived membranes, hydrogel, and sponge in an animal model

Leticia Ramos Dantas, Eduardo Buscarons de Andrade, Giovana Neves Tagliari, Giovanna Rosendo Pereira, Luana Czlusniak Godoy, Maria Eduarda Martins Gomes, Victoria Camargo Cachoeira, Marcelo de Paula Loureiro, Thais Andrade Costa Casagrande, Gustavo Henrique Loesch, Maíra de Mayo Oliveira Nogueira Loesch and Felipe Francisco Tuon

Burns, 2025, 51, 107522
DOI: 10.1016/j.burns.2025.107522

Zinc Ion‐Releasing Gelatin‐Based Bioadhesives for Wound Management

Sung Eun Kim, Yeonjeong Kim, Dong‐Wook Han and Kyung Min Park

Small Structures, 2025
DOI: 10.1002/sstr.202500286

Stimuli-Responsive Polysaccharide-Based Smart Hydrogels and Their Emerging Applications

Nandita Srivastava and Anirban Roy Choudhury

Ind. Eng. Chem. Res., 2023, 62, 841
DOI: 10.1021/acs.iecr.2c02779

A novel wound dressing material: Pullulan grafted copolymer hydrogel via UV copolymerization and crosslinking

Humeyra Mert, Bengi Özkahraman and Hüdanur Damar

Journal of Drug Delivery Science and Technology, 2020, 60, 101962
DOI: 10.1016/j.jddst.2020.101962

Polysaccharides as submucosal injection materials (SIMs) in endoscopic resection: A comprehensive review

Yaochen Yang, Tingting Wang, Miaomiao Xiao, Zhipeng Hou, Yang Liu, Kai Zhang, Liqun Yang and Siyu Sun

Carbohydrate Polymers, 2025, 355, 123360
DOI: 10.1016/j.carbpol.2025.123360

A renewable hydrogel electrolyte membrane prepared by carboxylated chitosan and polyacrylamide for solid-state supercapacitors with wide working temperature range

Xiangya Wang, Qianqian Zhang, Lei Zhao, Mohammed Kamal Hadi, Sangaraju Sambasivam, Qi Zhou and Fen Ran

Journal of Power Sources, 2023, 560, 232704
DOI: 10.1016/j.jpowsour.2023.232704

Polysaccharide-Based Hydrogels for Advanced Biomedical Engineering Applications

Md. Mahamudul Hasan Rumon, Anwarul Azim Akib, Stephen Don Sarkar, Md. Abu Rayhan Khan, Md. Mosfeq Uddin, Dina Nasrin and Chanchal Kumar Roy

ACS Polym. Au, 2024, 4, 463
DOI: 10.1021/acspolymersau.4c00028

CO2-Mediated Alkali-Neutralization Curdlan Hydrogels for Potential Wound Healing Application

Haiyan Wang, Bohao Yin, Wenjun Sun, Huanna Geng, Mingyue Wang, Yahui Li, Hui Sun, Xuexia Yang and Siyu Ni

Biomacromolecules, 2024, 25, 1738
DOI: 10.1021/acs.biomac.3c01233

Ultrasound-assisted enzymatic hydrolysis of yeast β-glucan catalyzed by β-glucanase: Chemical and microstructural analysis

Hongjie Yuan, Yan He, Hua Zhang and Xia Ma

Ultrasonics Sonochemistry, 2022, 86, 106012
DOI: 10.1016/j.ultsonch.2022.106012

Fundamental concepts of injectable hydrogel based on natural polymer for malignant solid tumor: Types and characterization – Review

Eduard A. Córdoba, Natalia A. Agudelo and Claudia E. Echeverri-Cuartas

Journal of Drug Delivery Science and Technology, 2025, 105, 106587
DOI: 10.1016/j.jddst.2024.106587

Highly adhesive and dual-crosslinking hydrogel via one-pot self-initiated polymerization for efficient antibacterial, antifouling and full-thickness wound healing

Nuoya Zhao and Weizhong Yuan

Composites Part B: Engineering, 2022, 230, 109525
DOI: 10.1016/j.compositesb.2021.109525

Smart nano-in-microparticles to tackle bacterial infections in skin tissue engineering

Marco Ruggeri, Barbara Vigani, Cinzia Boselli, Antonia Icaro Cornaglia, Daniele Colombo, Rita Sànchez-Espejo, Elena Del Favero, Narcisa Mandras, Janira Roana, Lorenza Cavallo, Laura Cantù, Cesar Viseras, Silvia Rossi and Giuseppina Sandri

Materials Today Bio, 2022, 16, 100418
DOI: 10.1016/j.mtbio.2022.100418

Multifunctional chitosan/alginate hydrogel incorporated with bioactive glass nanocomposites enabling photothermal and nitric oxide release activities for bacteria-infected wound healing

Man Zhang, Zunqing Fan, Jie Zhang, Yilei Yang, Changbao Huang, Weifen Zhang, Dejun Ding, Guoyan Liu and Ni Cheng

International Journal of Biological Macromolecules, 2023, 232, 123445
DOI: 10.1016/j.ijbiomac.2023.123445

Hybrid double-network dual-crosslinked hydrogel with self-healing ability and mechanical stability. Synthesis, characterization and application for motion sensors

Samaneh Khodami, Klaudia Kaniewska, Zbigniew Stojek and Marcin Karbarz

European Polymer Journal, 2022, 173, 111258
DOI: 10.1016/j.eurpolymj.2022.111258

Nucleoside-Based Cross-Linkers for Hydrogels with Tunable Properties

Rafael Itzhakov, Dmitry Tworowski, Noy Sadot, Tali Sayas, Elazar Fallik, Maya Kleiman and Elena Poverenov

ACS Appl. Mater. Interfaces, 2023, 15, 7359
DOI: 10.1021/acsami.2c19525

Cellular Interaction of Human Skin Cells towards Natural Bioink via 3D-Bioprinting Technologies for Chronic Wound: A Comprehensive Review

Syafira Masri, Mazlan Zawani, Izzat Zulkiflee, Atiqah Salleh, Nur Izzah Md Fadilah, Manira Maarof, Adzim Poh Yuen Wen, Fatih Duman, Yasuhiko Tabata, Izhar Abd Aziz, Ruszymah Bt Hj Bt Hj Idrus and Mh Busra Fauzi

IJMS, 2022, 23, 476
DOI: 10.3390/ijms23010476

Biomedical applications of functional hydrogels: Innovative developments, relevant clinical trials and advanced products

Katrin Zöller, Dennis To and Andreas Bernkop-Schnürch

Biomaterials, 2025, 312, 122718
DOI: 10.1016/j.biomaterials.2024.122718

Stimuli-responsive polysaccharide-based smart hydrogels for diabetic wound healing: Design aspects, preparation methods and regulatory perspectives

Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P.S. Rajinikanth, Vidya Tickoo and Saurabh Srivastava

Carbohydrate Polymers, 2024, 324, 121537
DOI: 10.1016/j.carbpol.2023.121537

Modular Functionalization of Laminarin to Create Value-Added Naturally Derived Macromolecules

Ana M. S. Costa, João M. M. Rodrigues, Maria M. Pérez-Madrigal, Andrew P. Dove and João F. Mano

J. Am. Chem. Soc., 2020, 142, 19689
DOI: 10.1021/jacs.0c09489

Marine Polysaccharides as a Versatile Biomass for the Construction of Nano Drug Delivery Systems

Ying Sun, Xiaoli Ma and Hao Hu

Marine Drugs, 2021, 19, 345
DOI: 10.3390/md19060345

Stimulus-responsive polysaccharide-based hydrogels: From design to biomedical applications

Yao Li, Xiaokang Ding, Hao Hu and Fu-Jian Xu

Precision Medicine and Engineering, 2024, 1, 100001
DOI: 10.1016/j.preme.2024.100001

State-of-the-Art Review of Electrospun Gelatin-Based Nanofiber Dressings for Wound Healing Applications

Tao Li, Mingchao Sun and Shaohua Wu

Nanomaterials, 2022, 12, 784
DOI: 10.3390/nano12050784

Algal Biomass-Loaded Hydrogel Scaffolds as a Biomimetic Platform with Antibacterial and Wound Healing Activities

Aakanksha Agarwal, Arun Kumar, Piyush Garg, Arnab Chakraborty, Ranjan Verma, Maryam Sarwat, Ajay Gupta, Pijus K. Sasmal, Yogesh Kumar Verma, Chiranjit Chowdhury and Monalisa Mukherjee

ACS Appl. Polym. Mater., 2022, 4, 5800
DOI: 10.1021/acsapm.2c00722

Polymer-Based Wound Dressings Loaded with Essential Oil for the Treatment of Wounds: A Review

Bruna Michele A. de B. Buriti, Pablo Luis B. Figueiredo, Marcele Fonseca Passos and Joyce Kelly R. da Silva

Pharmaceuticals, 2024, 17, 897
DOI: 10.3390/ph17070897

Polysaccharide-based hydrogels: properties, advantages, challenges, and optimization methods for applications in regenerative medicine

Pooria Safarzadeh Kozani, Pouya Safarzadeh Kozani, Masoud Hamidi, Oseweuba Valentine Okoro, Morteza Eskandani and Mehdi Jaymand

International Journal of Polymeric Materials and Polymeric Biomaterials, 2022, 71, 1319
DOI: 10.1080/00914037.2021.1962876

Polysaccharide-modified bactericidal and fouling-resistant cotton gauze for potential application as a wound dressing

Madhusmita Sahoo, Milan Paul, Prafful P. Kothari, Meghana Varanasi, Swati Biswas and Debirupa Mitra

Carbohydrate Polymer Technologies and Applications, 2024, 7, 100437
DOI: 10.1016/j.carpta.2024.100437

A macromolecular cross-linked alginate aerogel with excellent concentrating effect for rapid hemostasis

Huanxuan Huang, Shiyang Liao, Dong Zhang, Wencheng Liang, Keqing Xu, Yadong Zhang and Meidong Lang

Carbohydrate Polymers, 2024, 338, 122148
DOI: 10.1016/j.carbpol.2024.122148

Designing carrageenan-based functional biomaterials by supra-molecular and covalent interactions for biomedical applications

Nistha Thakur and Baljit Singh

Medicine in Novel Technology and Devices, 2024, 24, 100338
DOI: 10.1016/j.medntd.2024.100338

The effect of molecular weight and chemical structure of cross-linkers on the properties of redox-responsive hyaluronic acid hydrogels

Trung Thang Vu, Muhammad Gulfam, Sung-Han Jo, Ali Rizwan, Soo-Bin Joo, Bonggi Lee, Sang-Hyug Park and Kwon Taek Lim

International Journal of Biological Macromolecules, 2023, 238, 124285
DOI: 10.1016/j.ijbiomac.2023.124285

Flexible Bicolorimetric Polyacrylamide/Chitosan Hydrogels for Smart Real‐Time Monitoring and Promotion of Wound Healing

Kaikai Zheng, Yu Tong, Shihao Zhang, Ruiying He, Lan Xiao, Zoya Iqbal, Yuhong Zhang, Jie Gao, Lei Zhang, Libo Jiang and Yulin Li

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202102599

Pullulan/Poly(vinyl alcohol) Hydrogels Loaded with Calendula officinalis Extract: Design and In Vitro Evaluation for Wound Healing Applications

Irina Mihaela Pelin, Mihaela Silion, Irina Popescu, Cristina Mihaela Rîmbu, Gheorghe Fundueanu and Marieta Constantin

Pharmaceutics, 2023, 15, 1674
DOI: 10.3390/pharmaceutics15061674

Ultrashort Peptides and Hyaluronic Acid-Based Injectable Composite Hydrogels for Sustained Drug Release and Chronic Diabetic Wound Healing

Ling Wang, Jing Li, Yue Xiong, Yihang Wu, Fen Yang, Ying Guo, Zhaolin Chen, Liqian Gao and Wenbin Deng

ACS Appl. Mater. Interfaces, 2021, 13, 58329
DOI: 10.1021/acsami.1c16738

Exploring polysaccharide-based bio-adhesive topical film as a potential platform for wound dressing application: A review

Sakshi Priya, Manisha Choudhari, Yashika Tomar, Vaibhavi Meghraj Desai, Srinath Innani, Sunil Kumar Dubey and Gautam Singhvi

Carbohydrate Polymers, 2024, 327, 121655
DOI: 10.1016/j.carbpol.2023.121655

Wound Microenvironment-Responsive Protein Hydrogel Drug-Loaded System with Accelerating Healing and Antibacterial Property

Rong Zhang, Yongchang Tian, Long Pang, Taimin Xu, Bing Yu, Hailin Cong and Youqing Shen

ACS Appl. Mater. Interfaces, 2022, 14, 10187
DOI: 10.1021/acsami.2c00373

One-pot synthesis of injectable freeze-dried platelet lysate functionalized peptides hydrogel for pressure ulcers repair

Kun Liu, Lei Wang, Dongdong Li, Fengying Qi, Shaoduo Yan, Xiaoyang Yi, Yanhong Li, Yuyuan Ma, Xian Su, Yuxin Zhang, Xunuo Li, Ruotong Zhang, Shuo Liang, Jialu Sun, Weiming Wang, Xiangzhi Jia, Guang Li and Qiuxia Fu

Chemical Engineering Journal, 2025, 522, 167275
DOI: 10.1016/j.cej.2025.167275

Functional Hydrogels as Wound Dressing to Enhance Wound Healing

Yongping Liang, Jiahui He and Baolin Guo

ACS Nano, 2021, 15, 12687
DOI: 10.1021/acsnano.1c04206

Trends in the Treatment of Chronic Wounds

Rohit Sharma, Jan Hruska, Lukas Peter, Kristina Randlova and Kamil Kuca

CMC, 2025, 32, 5370
DOI: 10.2174/0109298673312649240829103906

Polysaccharide-based nanocarriers for efficient transvascular drug delivery

Min Zhang, He Ma, Xijie Wang, Bing Yu, Hailin Cong and Youqing Shen

Journal of Controlled Release, 2023, 354, 167
DOI: 10.1016/j.jconrel.2022.12.051

Carboxymethyl cellulose-based hydrogel film combined with berberine as an innovative tool for chronic wound management

S. Cometa, C. Licini, M.A. Bonifacio, P. Mastrorilli, M. Mattioli-Belmonte and E. De Giglio

Carbohydrate Polymers, 2022, 283, 119145
DOI: 10.1016/j.carbpol.2022.119145

Promoting oral mucosal wound healing using a DCS-RuB2A2 hydrogel based on a photoreactive antibacterial and sustained release of BMSCs

Wenxin Qi, Naijun Dong, Lingling Wu, Xueqi Zhang, He Li, Hao Wu, Natalie Ward, Jian Yu, He Liu, Jiao Wang, Xiaoyong Deng and Robert Chunhua Zhao

Bioactive Materials, 2023, 23, 53
DOI: 10.1016/j.bioactmat.2022.10.027

Preparation of oxidized hyaluronic acid based antibacterial material and its hydrogel by dynamic imine linkage

Mengli Wang, Yang Fu, Xuemei Zhang, Chao Geng, Zhen Lv, Shuai Wang, Chen Wang, Kai Yang, Guoxing Xu and Shixue Wang

European Polymer Journal, 2025, 236, 114135
DOI: 10.1016/j.eurpolymj.2025.114135

Design and development of a novel PVA/CS/MOP ionic conductive hydrogel for flexible sensors: fabrication, characterization, and performance evaluation

Wenjun Xu, Md All Amin Newton, Binjie Xin and Zhuoming Chen

J Mater Sci, 2024, 59, 1104
DOI: 10.1007/s10853-023-09255-z

Interfacial assembly of chitin/Mn3O4 composite hydrogels as photothermal antibacterial platform for infected wound healing

Hongli Zhang, Mengqing Xu, Haihua Luo, Shuangquan Wu, Xiaofang Gao, Qiong Wu, Huan Xu and Yi Liu

International Journal of Biological Macromolecules, 2023, 243, 124362
DOI: 10.1016/j.ijbiomac.2023.124362

Cryogel wound dressings based on natural polysaccharides perfectly adhere to irregular wounds for rapid haemostasis and easy disassembly

Changchun Liu, Jiaqi Liu, Minmin Wu, Haifeng Ni, Jie Feng, Liping Zhao and Jing Zhang

Wound Repair Regeneration, 2024, 32, 393
DOI: 10.1111/wrr.13173

A review of thermosensitive polysaccharide-based composite hydrogels for therapeutic applications

Morgane Morel, Virginie Dulong, Anne-Claire Groo, Aurélie Malzert-Fréon and Luc Picton

International Journal of Biological Macromolecules, 2025, 319, 145292
DOI: 10.1016/j.ijbiomac.2025.145292

Bioadhesive hydrogel comprising bilirubin/β-cyclodextrin inclusion complexes promote diabetic wound healing

Qing Yao, Yannan Shi, Xing Xia, Yingying Tang, Xue Jiang, Ya-Wen Zheng, Hailin Zhang, Ruijie Chen and Longfa Kou

Pharmaceutical Biology, 2021, 59, 1137
DOI: 10.1080/13880209.2021.1964543

Mechanically strong and on-demand dissoluble chitosan hydrogels for wound dressing applications

Ying Luo, Lei Cui, Lei Zou, Yiping Zhao, Li Chen, Ying Guan and Yongjun Zhang

Carbohydrate Polymers, 2022, 294, 119774
DOI: 10.1016/j.carbpol.2022.119774

PAMAM-Functionalized Cellulose Nanocrystals with Needle-Like Morphology for Effective Cancer Treatment

Yanzhen Sun, Xiaoli Ma, Xiaodong Jing and Hao Hu

Nanomaterials, 2021, 11, 1640
DOI: 10.3390/nano11071640

Recent insights into polysaccharide-based hydrogels and their potential applications in food sector: A review

Arshied Manzoor, Aamir Hussain Dar, Vinay Kumar Pandey, Rafeeya Shams, Sadeeya Khan, Parmjit S. Panesar, John F. Kennedy, Ufaq Fayaz and Shafat Ahmad Khan

International Journal of Biological Macromolecules, 2022, 213, 987
DOI: 10.1016/j.ijbiomac.2022.06.044

Bioactive wound dressing based on decellularized tendon and GelMA with incorporation of PDA-loaded asiaticoside nanoparticles for scarless wound healing

Shuang Liu, Yingsong Zhao, Ming Li, Lei Nie, Qianqian Wei, Oseweuba Valentine Okoro, Hafez Jafari, Siyuan Wang, Jun Deng, Jianghai Chen, Amin Shavandi and Lihong Fan

Chemical Engineering Journal, 2023, 466, 143016
DOI: 10.1016/j.cej.2023.143016

Gamma‐Ray Induced, Superabsorbent, and Reusable Polyethylene Oxide/Starch/4‐Styrenesulfonic Acid Sodium Salt Hydrogel for the Removal of Cationic Dyes and Chromium (III) Ion

Sakib Hossain Bhuiyan, Md. Saifur Rahaman, Tanvir Ahmed, Shah Md. Marzuk Hasnine, Sadia Afroz, Monia Jannatul Kubra, Salma Sultana, Moriom Afiza, Makoto Takafuji and Md. Ashraful Alam

J of Applied Polymer Sci, 2025, 142
DOI: 10.1002/app.57376

Blends of Silk Waste Protein and Polysaccharides for Enhanced Wound Healing and Tissue Regeneration: Mechanisms, Applications, and Future Perspectives

Devipriya Vasudevan and D. Sangeetha

ACS Omega, 2024, 9, 44101
DOI: 10.1021/acsomega.4c06518

Integrating supercapacitor with sodium hyaluronate based hydrogel as a novel All-In-One wound Dressing: Self-Powered electronic stimulation

Xiangya Wang, Weijie Zhang, Qi Zhou and Fen Ran

Chemical Engineering Journal, 2023, 452, 139491
DOI: 10.1016/j.cej.2022.139491

Recent Advances of Natural-Polymer-Based Hydrogels for Wound Antibacterial Therapeutics

Yue Zhao, Xiaoyu Wang, Ruilian Qi and Huanxiang Yuan

Polymers, 2023, 15, 3305
DOI: 10.3390/polym15153305

An extracellular matrix-inspired self-healing composite hydrogel for enhanced platelet-rich plasma-mediated chronic diabetic wound treatment

Ya Zhang, Zi-Li Wang, Ze-Peng Deng, Zi-Lin Wang, Fei Song and Li-Li Zhu

Carbohydrate Polymers, 2023, 315, 120973
DOI: 10.1016/j.carbpol.2023.120973

3D printed drug loaded nanomaterials for wound healing applications

Ashagrachew Tewabe Yayehrad, Ebrahim Abdella Siraj, Motlalepula Matsabisa and Gebremariam Birhanu

Regenerative Therapy, 2023, 24, 361
DOI: 10.1016/j.reth.2023.08.007

Antioxidant and anti-inflammatory activities of Prussian blue nanozyme promotes full-thickness skin wound healing

Abhishek Sahu, Jin Jeon, Min Suk Lee, Hee Seok Yang and Giyoong Tae

Materials Science and Engineering: C, 2021, 119, 111596
DOI: 10.1016/j.msec.2020.111596

Nanomaterials-Functionalized Hydrogels for the Treatment of Cutaneous Wounds

Yangkun Liu, Gongmeiyue Su, Ruoyao Zhang, Rongji Dai and Zhao Li

IJMS, 2022, 24, 336
DOI: 10.3390/ijms24010336

Strontium ranelate-loaded human hair keratin-hyaluronic acid hydrogel accelerates wound repair with anti-inflammatory and antioxidant properties

Cuicui Han, Miaomiao Zhang, ShiXin Xu, Chengwei Wang, Bo Li and Wen Zhao

International Journal of Biological Macromolecules, 2024, 281, 136536
DOI: 10.1016/j.ijbiomac.2024.136536

Ciprofloxacin carrier systems based on hectorite/halloysite hybrid hydrogels for potential wound healing applications

Marina Massaro, Ana Borrego-Sánchez, Rita Sánchez-Espejo, César Viseras Iborra, Giuseppe Cavallaro, Fátima García-Villén, Susanna Guernelli, Giuseppe Lazzara, Dalila Miele, C. Ignacio Sainz-Díaz, Giuseppina Sandri and Serena Riela

Applied Clay Science, 2021, 215, 106310
DOI: 10.1016/j.clay.2021.106310

Antimicrobial and wound healing activities of electrospun nanofibers based on functionalized carbohydrates and proteins

Mehran Alavi and Ali Nokhodchi

Cellulose, 2022, 29, 1331
DOI: 10.1007/s10570-021-04412-6

Designing of tragacanth gum-poly(2-(methacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide) and poly(acrylamide) based hydrogels for drug delivery and wound dressing applications

Kavita Devi, Ashima Sharma, Rajesh Kumar and Baljit Singh

Medicine in Novel Technology and Devices, 2024, 22, 100303
DOI: 10.1016/j.medntd.2024.100303

Application of 3D printing in the treatment of diabetic foot ulcers: current status and new insights

Xinrui Li, Xin Ai, Bo Wang, Mengqian Luo, Akira Miyamoto, Mohammad Shafi Kuchay, Dechao Feng and Chi Zhang

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1475885

Alginate/hyaluronic acid-based systems as a new generation of wound dressings: A review

Nazanin Zarei and S.A. Hassanzadeh-Tabrizi

International Journal of Biological Macromolecules, 2023, 253, 127249
DOI: 10.1016/j.ijbiomac.2023.127249

Click chemistry-based biopolymeric hydrogels for regenerative medicine

Ya Li, Xiaonan Wang, Yuanyuan Han, Hung-Yu Sun, Jöns Hilborn and Liyang Shi

Biomed. Mater., 2021, 16, 022003
DOI: 10.1088/1748-605X/abc0b3

Fabrication and evaluation of Cs/PVP sponge containing platelet-rich fibrin as a wound healing accelerator: An in vitro and in vivo study

Mohamadreza Tavakoli, Marjan Mirhaj, Sheyda Labbaf, Jaleh Varshosaz, Somayeh Taymori, Franoosh Jafarpour, Saeedeh Salehi, Shaghayegh Amini Mosleh Abadi and Azadeh Sepyani

International Journal of Biological Macromolecules, 2022, 204, 245
DOI: 10.1016/j.ijbiomac.2022.02.003

Bioadhesives based on multifunctional biopolymers for biomedical applications

Seoyoon Yu and Chaenyung Cha

Macromol. Res., 2023, 31, 427
DOI: 10.1007/s13233-023-00141-w

In-situ formed elastin-based hydrogels enhance wound healing via promoting innate immune cells recruitment and angiogenesis

Duo-Mei Tian, Huan-Huan Wan, Jia-Reng Chen, Yong-Bin Ye, Yong He, Yu Liu, Lu-Yao Tang, Zhong-Yuan He, Kai-Zheng Liu, Chong-Jian Gao, Sheng-Lin Li, Qian Xu, Zheng Yang, Chen Lai, Xiao-Jun Xu, Chang-Shun Ruan, Yun-Sheng Xu, Chao Zhang, Liang Luo and Le-Ping Yan

Materials Today Bio, 2022, 15, 100300
DOI: 10.1016/j.mtbio.2022.100300

Multifunctional Dressing for Wound Diagnosis and Rehabilitation

Ning Tang, Youbin Zheng, Daxiang Cui and Hossam Haick

Adv Healthcare Materials, 2021, 10
DOI: 10.1002/adhm.202101292

Polymers and Bioactive Compounds with a Macrophage Modulation Effect for the Rational Design of Hydrogels for Skin Regeneration

Mirna L. Sánchez, Hugo Valdez, Micaela Conde, Pamela Viaña-Mendieta and Aldo R. Boccaccini

Pharmaceutics, 2023, 15, 1655
DOI: 10.3390/pharmaceutics15061655

O-carboxymethyl chitosan in biomedicine: A review

Lingbin Chen, Yandi Xie, Xiaohang Chen, Hengyi Li, Youguang Lu, Hao Yu and Dali Zheng

International Journal of Biological Macromolecules, 2024, 275, 133465
DOI: 10.1016/j.ijbiomac.2024.133465

Multifunctional hydrogels for wound dressings using xanthan gum and polyacrylamide

Song Tang, Zhoujie Gong, Zefan Wang, Xia Gao and Xiaonan Zhang

International Journal of Biological Macromolecules, 2022, 217, 944
DOI: 10.1016/j.ijbiomac.2022.07.181

Diversified antibacterial modification and latest applications of polysaccharide-based hydrogels for wound healthcare

Rong Zhang, Bing Yu, Yongchang Tian, Long Pang, Taimin Xu, Hailin Cong and Youqing Shen

Applied Materials Today, 2022, 26, 101396
DOI: 10.1016/j.apmt.2022.101396

Antibacterial Hybrid Hydrogels

Zhongming Cao, Yue Luo, Zhaoyang Li, Lei Tan, Xiangmei Liu, Changyi Li, Yufeng Zheng, Zhenduo Cui, Kelvin Wai Kwok Yeung, Yanqin Liang, Shengli Zhu and Shuilin Wu

Macromolecular Bioscience, 2021, 21
DOI: 10.1002/mabi.202000252

Engineering Polysaccharides for Tissue Repair and Regeneration

Pingli Wu, Xin Xi, Ruochen Li and Guoming Sun

Macromolecular Bioscience, 2021, 21
DOI: 10.1002/mabi.202100141

DMARDS incorporated injectable hydrogels in cartilage tissue regeneration: a review

Urwa Ayaz, Muhammad Zaman, Huma Hameed, Saba Naeem, Iqra Noor Khan, Muhammad Ahsan Waqar, Sania Niaz, Nelofer Ereej and Ahmad Salawi

Polymer-Plastics Technology and Materials, 2024, 63, 1843
DOI: 10.1080/25740881.2024.2360170

Constructing of pH and reduction dual-responsive folic acid-modified hyaluronic acid-based microcapsules for dual-targeted drug delivery via sonochemical method

Qingye Meng, Shuangling Zhong, Shihao He, Yan Gao and Xuejun Cui

Colloid and Interface Science Communications, 2021, 44, 100503
DOI: 10.1016/j.colcom.2021.100503

Plasma-Functionalised Dressings for Enhanced Wound Healing

Xanthe L. Strudwick, Jason D. Whittle, Allison J. Cowin and Louise E. Smith

IJMS, 2023, 24, 797
DOI: 10.3390/ijms24010797

Biomedical Applications and Nutritional Value of Specific Food-Derived Polysaccharide-Based Hydrogels

Qianru Xiang, Yuting Hao, Zijun Xia, Meiqi Liao, Xinkai Rao, Shenghui Lao, Qi He, Congshun Ma and Wenzhen Liao

Advances in Nutrition, 2024, 15, 100309
DOI: 10.1016/j.advnut.2024.100309

Physical crosslinking of hydrogels: The potential of dynamic and reversible bonds in burn care

Mariana Marques Ribeiro, Marco Simões, Carla Vitorino and Filipa Mascarenhas-Melo

Coordination Chemistry Reviews, 2025, 542, 216868
DOI: 10.1016/j.ccr.2025.216868

Dynamic Microenvironment-Adaptable Hydrogel with Photothermal Performance and ROS Scavenging for Management of Diabetic Ulcer

Xinxin Jia, Jie Li, Yin Zheng, Xiaopeng Yang, Tingting Che, Jun Zhang, Yuanyuan Zhang, Xinge Zhang and Zhongming Wu

ACS Appl. Mater. Interfaces, 2023, 15, 49974
DOI: 10.1021/acsami.3c09182

Antibiotic-free combinational hyaluronic acid blend nanofibers for wound healing enhancement

Mohamed R. El-Aassar, Nagham G. El-Beheri, Mona M. Agwa, Hoda M. Eltaher, Mostafa Alseqely, Wagih S. Sadik and Labiba El-Khordagui

International Journal of Biological Macromolecules, 2021, 167, 1552
DOI: 10.1016/j.ijbiomac.2020.11.109

Advancements in hydrogels: A comprehensive review of natural, synthetic, and hybrid innovations for wound healing

Saadullah Khattak, Ihsan Ullah, Muhammad Tufail Yousaf, Salim Ullah, Humayun Yousaf, Yutong Li, Haoyu Jin, Jianliang Shen and Hong-Tao Xu

International Journal of Biological Macromolecules, 2025, 327, 147270
DOI: 10.1016/j.ijbiomac.2025.147270

Hyaluronic acid-based injectable nanocomposite hydrogels with photo-thermal antibacterial properties for infected chronic diabetic wound healing

Xu Yang, Suisui He, Jun Wang, Ying Liu, Wei Ma, Cui-Yun Yu and Hua Wei

International Journal of Biological Macromolecules, 2023, 242, 124872
DOI: 10.1016/j.ijbiomac.2023.124872

Gum arabic based multifunctional antibacterial adhesion hydrogel dressings loaded with doxycycline hydrochloride for wound healing

Yan Ding, Qida Zong, Qianwen Zhang, Ye Wang, Jiaxin Wang, Wanru Huang, Wei Sun and Yinglei Zhai

International Journal of Biological Macromolecules, 2025, 306, 141284
DOI: 10.1016/j.ijbiomac.2025.141284

A Choline Phosphoryl-Conjugated Chitosan/Oxidized Dextran Injectable Self-Healing Hydrogel for Improved Hemostatic Efficacy

Ziran Zhu, Kaiwen Zhang, Yiwen Xian, Gang He, Zheng Pan, Hufei Wang, Chong Zhang and Decheng Wu

Biomacromolecules, 2023, 24, 690
DOI: 10.1021/acs.biomac.2c01143

Recent trends in hydrogel-based formulation for the treatment of diabetic wounds: A review

Bedanta Bhattacharjee, Sandhanam K, Damanbhalang Rynjah, Pratap Kalita, Arzoo Newar, Karabi Kalita, Satyabrat Sarma, Partha Pratim Dutta, Manas Jyoti Kapil, Abdul Baquee Ahmed and Ram Kumar Sahu

Journal of Drug Delivery Science and Technology, 2025, 107, 106848
DOI: 10.1016/j.jddst.2025.106848

Role of Hydrophobic Associations in Self-Healing Hydrogels Based on Amphiphilic Polysaccharides

Marieta Nichifor

Polymers, 2023, 15, 1065
DOI: 10.3390/polym15051065

Advances in the development of medical dressings for the treatment of diabetic foot wounds

Ming Cai, Zhao Liu, Xun Sun, Ying Qi, Xiaolong Mei, Su Liu, Chunlin Zhang, Xin Zhang, Zhiguo Zong, Pengpeng Ma, Tao Wang, Weiguo Xu and Tao Zhang

Chemical Engineering Journal, 2024, 498, 155575
DOI: 10.1016/j.cej.2024.155575

Radiation cross-linked collagen scaffolds facilitate root coverage and keratinized gingival regeneration

Hongwei Li, Xin Chen, Bozhao Wang, Caiming Wu, Jian Li and Ling Xu

Bioactive Materials, 2025, 51, 138
DOI: 10.1016/j.bioactmat.2025.04.023

Advances in chitosan-based wound dressings: Modifications, fabrications, applications and prospects

Maocheng Ji, Jianyong Li, Yi Wang, Fangyi Li, Jia Man, Jianfeng Li, Chuanwei Zhang, Sixian Peng and Shiqing Wang

Carbohydrate Polymers, 2022, 297, 120058
DOI: 10.1016/j.carbpol.2022.120058

Towards superior biopolymer gels by enabling interpenetrating network structures: A review on types, applications, and gelation strategies

Xinran Hou, Lisong Lin, Kexin Li, Fatang Jiang, Dongling Qiao, Binjia Zhang and Fengwei Xie

Advances in Colloid and Interface Science, 2024, 325, 103113
DOI: 10.1016/j.cis.2024.103113

Wound healing effects of β-lapachone-loaded liposomal hydrogel based on bacterial cellulose and hydroxyethylcellulose

Sarah Brandão Palácio, Marília Evellyn de Santana Dias, Daniel Charles dos Santos Macêdo, Rafaela de Siqueira Ferraz-Carvalho, Fábio José Fidélis Almeida, Luís André de Almeida Campos, Karitas Farias Alves Lima, Noemia Pereira da Silva Santos, Francisco Carlos de Amanajás Aguiar Junior, José Lamartine de Andrade Aguiar, Isabella Macário Ferro Cavalcanti and Nereide Stela Santos-Magalhães

Next Research, 2025, 2, 100651
DOI: 10.1016/j.nexres.2025.100651

Natural Soybean Milk-Derived Bioactive Coatings for Enhanced Wound Healing

Peikun Xin, Shuyan Han, Jun Huang, Xinru You and Jun Wu

ACS Appl. Mater. Interfaces, 2022, 14, 34480
DOI: 10.1021/acsami.2c09689

Oxydextran-based photodynamic antibacterial nanoplatform with broad-Spectrum antibacterial activity

Yongchang Tian, Rong Zhang, Binbin Guan, Yaowei Zhu and Li Chen

International Journal of Biological Macromolecules, 2023, 236, 123917
DOI: 10.1016/j.ijbiomac.2023.123917

Injectable antibacterial antiinflammatory molecular hybrid hydrogel dressing for rapid MDRB-infected wound repair and therapy

Wei Cheng, Min Wang, Mi Chen, Wen Niu, Yannan Li, Yidan Wang, Meng Luo, Chenxi Xie, Tongtong Leng and Bo Lei

Chemical Engineering Journal, 2021, 409, 128140
DOI: 10.1016/j.cej.2020.128140

Bio-fabrication of chitosan-stabilized magnesium oxide nanomaterials: Investigation of photocatalytic, in vitro cytotoxicity activities and apoptosis in oral squamous carcinoma cells

Chandramohan Govindasamy, Muhammad Ibrar Khan, Samer Hasan Hussein-Al-Ali, Qais Abualassal, Zead helmi Abudayeh, Palanisamy Arulselvan, Muruganantham Bharathi and Parthasarathy Surya

International Journal of Biological Macromolecules, 2025, 300, 139926
DOI: 10.1016/j.ijbiomac.2025.139926

Seaweed polysaccharide nanocomposite films: A review

Nur Thohiroh Md Bukhari, Nurul Fazita Mohammad Rawi, Nur Adilah Abu Hassan, Nur Izzaati Saharudin and Mohamad Haafiz Mohamad Kassim

International Journal of Biological Macromolecules, 2023, 245, 125486
DOI: 10.1016/j.ijbiomac.2023.125486

Polysaccharide Composite Alginate–Pectin Hydrogels as a Basis for Developing Wound Healing Materials

Galina A. Davydova, Leonid L. Chaikov, Nikolay N. Melnik, Radmir V. Gainutdinov, Irina I. Selezneva, Elena V. Perevedentseva, Muhriddin T. Mahamadiev, Vadim A. Proskurin, Daniel S. Yakovsky, Aurel George Mohan and Julietta V. Rau

Polymers, 2024, 16, 287
DOI: 10.3390/polym16020287

Photothermal‐enhanced in situ supramolecular hydrogel promotes bacteria‐infected wound healing in diabetes

Chen Zheng, Xuan Wu, Ming Liu, Yulong Lan, Qian Liu, Erya Cai, Zhiyong Liao and Jianliang Shen

Smart Medicine, 2024, 3
DOI: 10.1002/SMMD.20230047

Cryostructuring of Polymeric Systems. 55. Retrospective View on the More than 40 Years of Studies Performed in the A.N.Nesmeyanov Institute of Organoelement Compounds with Respect of the Cryostructuring Processes in Polymeric Systems

Vladimir I. Lozinsky

Gels, 2020, 6, 29
DOI: 10.3390/gels6030029

Porous Collagen Sponge Loaded with Large Efficacy-Potentiated Exosome-Mimicking Nanovesicles for Diabetic Skin Wound Healing

Xiangsheng Liu, Yufei Liu, Jie Zhou, Xinyi Yu, Jinpeng Wan, Jie Wang, Shaojin Lei, Zeyu Zhang, Lin Zhang and Shufang Wang

ACS Biomater. Sci. Eng., 2024, 10, 975
DOI: 10.1021/acsbiomaterials.3c01282

Antioxidant biocompatible composite collagen dressing for diabetic wound healing in rat model

Bei Qian, Jialun Li, Ke Guo, Nengqiang Guo, Aimei Zhong, Jie Yang, Jiecong Wang, Peng Xiao, Jiaming Sun and Lingyun Xiong

Regenerative Biomaterials, 2021, 8
DOI: 10.1093/rb/rbab003

Translational Applications of Hydrogels

Santiago Correa, Abigail K. Grosskopf, Hector Lopez Hernandez, Doreen Chan, Anthony C. Yu, Lyndsay M. Stapleton and Eric A. Appel

Chem. Rev., 2021, 121, 11385
DOI: 10.1021/acs.chemrev.0c01177

Polymer‐ and Lipid‐Based Nanostructures Serving Wound Healing Applications: A Review

Fatma N. Cetin, Arn Mignon, Sandra Van Vlierberghe and Kristyna Kolouchova

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202402699

Self-Healing Hydrogels: Development, Biomedical Applications, and Challenges

Md. Mahamudul Hasan Rumon, Anwarul Azim Akib, Fahmida Sultana, Md. Moniruzzaman, Mahruba Sultana Niloy, Md Salman Shakil and Chanchal Kumar Roy

Polymers, 2022, 14, 4539
DOI: 10.3390/polym14214539

Novel composite hydrogels prepared from carboxymethyl chitosan and polysaccharides extracted from Ononis natrix for controlled release of bioactive molecules

Nour Bhiri, Marie-Noëlle Labour, Suming Li, Rim Nasri, Moncef Nasri and Mohamed Hajji

International Journal of Biological Macromolecules, 2025, 318, 144880
DOI: 10.1016/j.ijbiomac.2025.144880

Polysaccharide-Based Nanoparticles for Colon-Targeted Drug Delivery Systems

Yubia De Anda-Flores, Elizabeth Carvajal-Millan, Alma Campa-Mada, Jaime Lizardi-Mendoza, Agustin Rascon-Chu, Judith Tanori-Cordova and Ana Luisa Martínez-López

Polysaccharides, 2021, 2, 626
DOI: 10.3390/polysaccharides2030038

Recent Advances in Topical Hemostatic Materials

Yang Liu, Yi Zhang, Weifeng Yao, Peidong Chen, Yudan Cao, Mingqiu Shan, Sheng Yu, Li Zhang, Beihua Bao and Fang-Fang Cheng

ACS Appl. Bio Mater., 2024, 7, 1362
DOI: 10.1021/acsabm.3c01144

Characterization and Biotechnological Potential of Extracellular Polysaccharides Synthesized by Alteromonas Strains Isolated from French Polynesia Marine Environments

Patrícia Concórdio-Reis, Vítor D. Alves, Xavier Moppert, Jean Guézennec, Filomena Freitas and Maria A. M. Reis

Marine Drugs, 2021, 19, 522
DOI: 10.3390/md19090522

Chitosan-based supramolecular aerogel with “skeletal structure” constructed in natural deep eutectic solvents for medical dressings

Xiangyu Sun, Yan Yang, Jiaming Yu, Qifeng Wei and Xiulian Ren

International Journal of Biological Macromolecules, 2024, 254, 127720
DOI: 10.1016/j.ijbiomac.2023.127720

Polysaccharide Electrospun Nanofibers for Wound Healing Applications

Guoxin Tan, Lijie Wang, Weisan Pan and Kai Chen

IJN, 2022, Volume 17, 3913
DOI: 10.2147/IJN.S371900

Progress in Polysaccharide-Based Hydrogels for Preventing Postoperative Adhesions: A Review

Mengyao Chen, Jialin Liu, Jianhong Lin, Kai Zhuang, Yudong Shan, Sandip Tiwari, Lei Jiang and Jiantao Zhang

Gels, 2025, 11, 188
DOI: 10.3390/gels11030188

Multifunctional carboxymethyl chitosan/oxidized carboxymethyl cellulose hydrogel loaded with ginsenoside Rg1 and polydopamine nanoparticles for infected diabetic wound healing

Sihui Li, Xiaofeng Ren, Youbo Liu, Li Wang, Yang Zhou, Yunan Zhang, Zhongyi Yan, Xiaorong Lan and Ling Guo

International Journal of Biological Macromolecules, 2024, 282, 136686
DOI: 10.1016/j.ijbiomac.2024.136686

Ion-Induced Polysaccharide Gelation: Peculiarities of Alginate Egg-Box Association with Different Divalent Cations

Anastasiya O. Makarova, Svetlana R. Derkach, Tahar Khair, Mariia A. Kazantseva, Yuriy F. Zuev and Olga S. Zueva

Polymers, 2023, 15, 1243
DOI: 10.3390/polym15051243

Aloe vera hydrogel for supercooling applications: a review

Modupeola Dada and Patricia Popoola

Discov Mater, 2024, 4
DOI: 10.1007/s43939-024-00080-y

Polysaccharide hydrogels: Functionalization, construction and served as scaffold for tissue engineering

Qian Yang, Jinrong Peng, Haitao Xiao, Xuewen Xu and Zhiyong Qian

Carbohydrate Polymers, 2022, 278, 118952
DOI: 10.1016/j.carbpol.2021.118952

Nanoarchitectonics of Bimetallic Cu-/Co-Doped Nitrogen–Carbon Nanozyme-Functionalized Hydrogel with NIR-Responsive Phototherapy for Synergistic Mitigation of Drug-Resistant Bacterial Infections

Sheng-Nan Song, Xin-Liu Zhao, Xiao-Chan Yang, Yong Ding, Feng-Di Ren, Xue-Yao Pang, Bo Li, Ji-Yuan Hu, Yu-Zhen Chen and Wei-Wei Gao

ACS Appl. Mater. Interfaces, 2024, 16, 16011
DOI: 10.1021/acsami.4c01783

Ultrafast Self‐Gelling, Adhesive, Anti‐Bacterial Coacervate‐Based Powders for Enhanced Hemostasis and Wound Healing

Hui Zhou, Bin Kong, Yi Cheng, Si Meng, Haifeng Dong, Cheng Qi, Tiantian Kong, Yuanjin Zhao and Zhou Liu

Small, 2025, 21
DOI: 10.1002/smll.202409164

Novel Sprayable Antioxidative Dressing Based on Fullerene and Curdlan for Accelerating Chronic Wound Healing

Yiwen Pan, Yuxuan Qi, Chenglong Fei, Zihang Feng, Yuguo Ma, Chunru Wang and Jingfen Han

Macromol. Rapid Commun., 2024, 45
DOI: 10.1002/marc.202400240

Recent Advancement of Functional Hydrogels toward Diabetic Wound Management

Krishanu Ghosal, Debojit Chakraborty, Victor Roychowdhury, Santanu Ghosh and Soumyarup Dutta

ACS Omega, 2022, 7, 43364
DOI: 10.1021/acsomega.2c05538

Review on design strategies and considerations of polysaccharide-based smart drug delivery systems for cancer therapy

Qingye Meng, Shuangling Zhong, Lifeng Xu, Jingfei Wang, Zhenqian Zhang, Yan Gao and Xuejun Cui

Carbohydrate Polymers, 2022, 279, 119013
DOI: 10.1016/j.carbpol.2021.119013

Hyaluronic Acid‐Based Injectable Hydrogels for Wound Dressing and Localized Tumor Therapy: A Review

Xu Yang, Bin Wang, Dongdong Peng, Xiaobo Nie, Jun Wang, Cui-Yun Yu and Hua Wei

Advanced NanoBiomed Research, 2022, 2
DOI: 10.1002/anbr.202200124

Glycosaminoglycan-Based Hydrogel Delivery System Regulates the Wound Microenvironment to Rescue Chronic Wound Healing

Xiang Zhang, Jin Feng, Weina Feng, Buxuan Xu, Kai Zhang, Guiping Ma, Yang Li, Maowei Yang and Fu-Jian Xu

ACS Appl. Mater. Interfaces, 2022, 14, 31737
DOI: 10.1021/acsami.2c08593

Oxidized Bletilla rhizome polysaccharide-based aerogel with synergistic antibiosis and hemostasis for wound healing

Quan Yan, Xiaoyan Long, Puxiang Zhang, Wei Lei, Dequn Sun and Xiaoying Ye

Carbohydrate Polymers, 2022, 293, 119696
DOI: 10.1016/j.carbpol.2022.119696

Chitosan and hyaluronic-based hydrogels could promote the infected wound healing

Que Bai, Qian Gao, Fangfang Hu, Caiyun Zheng, Wenting Chen, Na Sun, Jinxi Liu, Yanni Zhang, Xianglong Wu and Tingli Lu

International Journal of Biological Macromolecules, 2023, 232, 123271
DOI: 10.1016/j.ijbiomac.2023.123271

Injectable gelatin/oxidized dextran hydrogel loaded with apocynin for skin tissue regeneration

Shuaimeng Guan, Kun Zhang, Longlong Cui, Jiaheng Liang, Jingan Li and Fangxia Guan

Biomaterials Advances, 2022, 133, 112604
DOI: 10.1016/j.msec.2021.112604

Bioprinting a skin patch with dual-crosslinked gelatin (GelMA) and silk fibroin (SilMA): An approach to accelerating cutaneous wound healing

Lei Xu, Zhiqiang Zhang, Adam M. Jorgensen, Yuan Yang, Qianheng Jin, Guangliang Zhang, Gaobiao Cao, Yi Fu, Weixin Zhao, Jihui Ju and Ruixing Hou

Materials Today Bio, 2023, 18, 100550
DOI: 10.1016/j.mtbio.2023.100550

Fabrication of CMC-PVA-EGDE hydrogels for maintaining overall postharvest quality of small-size packaged straw mushroom

Rui Jin, Xin-Lin Li, Wei Jia, Wen Li, Lei Sun, Yan Yang, Jing-Song Zhang, Wen-Jing Sun and Feng-Jie Cui

Food Chemistry, 2025, 474, 143175
DOI: 10.1016/j.foodchem.2025.143175

Hydrogels and Nanogels: Pioneering the Future of Advanced Drug Delivery Systems

Ernesto J. Delgado-Pujol, Guillermo Martínez, David Casado-Jurado, Juan Vázquez, Jesús León-Barberena, David Rodríguez-Lucena, Yadir Torres, Ana Alcudia and Belén Begines

Pharmaceutics, 2025, 17, 215
DOI: 10.3390/pharmaceutics17020215

Recent Advances of Natural Polysaccharide‐based Double‐network Hydrogels for Tissue Repair

Hufei Wang, Xing Wang and Decheng Wu

Chemistry An Asian Journal, 2022, 17
DOI: 10.1002/asia.202200659

Epidermal growth factor-incorporated hydrogen bond crosslinked hemostatic microparticles capable of timely response to accidental bleeding for prehospital rescue

Wenguang Dou, Xiaojun Zeng, Chenyang Zhang, Xue Wang, Ye Zhu, Shuzhuang Zhu, Chan Liu, Weijun Ji, Qingmei Fan, Yonglin Gao, Kongyin Zhao, Jin Zhao, Xin Hou, Xubo Yuan, Hongliang Liu, Yansheng Li and Sidi Li

International Journal of Biological Macromolecules, 2024, 281, 136452
DOI: 10.1016/j.ijbiomac.2024.136452

Bioinspired Nanofibrous Glycopeptide Hydrogel Dressing for Accelerating Wound Healing: A Cytokine‐Free, M2‐Type Macrophage Polarization Approach

Zujian Feng, Qi Su, Chuangnian Zhang, Pingsheng Huang, Huijuan Song, Anjie Dong, Deling Kong and Weiwei Wang

Adv Funct Materials, 2020, 30
DOI: 10.1002/adfm.202006454

Synthesis, characterization and antibacterial properties of chitosan/Ag2S/CQDs hydrogel

Hongxia Li, Yongdong Liu, Xiang Gao, Xiaohui Niu, Haiyan Fan and Kunjie Wang

Chem. Pap., 2023, 77, 207
DOI: 10.1007/s11696-022-02470-z

Hydrogel Dressings: Multifunctional Solutions for Chronic Wound Healing; Focusing on In-Vivo Studies

Ahmad Mir Hosseini, Mohammad Amin Salim, Parisa Pourfaraziani, Mohadeseh Jamali, Negar Agahi, Alireza Azizi and Mahsa Mohammadian

J Lab Anim. Res, 2023, 2, 41
DOI: 10.58803/jlar.v2i5.28

Molecular design, synthesis strategies and recent advances of hydrogels for wound dressing applications

Dan Zeng, Shihong Shen and Daidi Fan

Chinese Journal of Chemical Engineering, 2021, 30, 308
DOI: 10.1016/j.cjche.2020.12.005

Smart wound dressing for advanced wound management: Real-time monitoring and on-demand treatment

Qian Pang, Fang Yang, Zilian Jiang, Kaihao Wu, Ruixia Hou and Yabin Zhu

Materials & Design, 2023, 229, 111917
DOI: 10.1016/j.matdes.2023.111917

Engineering Platelet‐Rich Plasma Based Dual‐Network Hydrogel as a Bioactive Wound Dressing with Potential Clinical Translational Value

Xiang Zhang, Dan Yao, Weiyi Zhao, Rui Zhang, Bingran Yu, Guiping Ma, Yang Li, Daifeng Hao and Fu‐Jian Xu

Adv Funct Materials, 2021, 31
DOI: 10.1002/adfm.202009258

Bletilla striata polysaccharide/ethanol extract composite hydrogel for accelerated wound healing

Zhengbo Hu, Kai Zhao, Fangmei Zhou, Xiaoqing Ye, Yuchi Chen, Lixia Jin, Xinming Ruan, Zhishan Ding and Bingqi Zhu

Journal of Materials Research, 2023, 38, 2495
DOI: 10.1557/s43578-023-00983-1

Nanofibrous Wound Healing Nanocomposite Based on Alginate Scaffold: In Vitro and In Vivo Study

Enyi Hu, Yihui Liang, Kangcha Chen, Xian Li and Jianhui Zhou

j biomed nanotechnol, 2022, 18, 2439
DOI: 10.1166/jbn.2022.3441

The Recent Progress of the Cellulose-Based Antibacterial Hydrogel

Ying Sun, Jiayi Wang, Duanxin Li and Feng Cheng

Gels, 2024, 10, 109
DOI: 10.3390/gels10020109

Microenvironment-responsive collagen hydrogel with Houttuynia Cordata Thunb vesicles for diabetic wound repair

Wenhao Yang, Zheng Xing, Xin Wang, Zhen Xu, Xiaolian Jiang, Jiang Xia, Lin Qiu, Jianda Xu and Jianhao Wang

International Journal of Biological Macromolecules, 2025, 320, 145840
DOI: 10.1016/j.ijbiomac.2025.145840

3D Matrices for Enhanced Encapsulation and Controlled Release of Anti-Inflammatory Bioactive Compounds in Wound Healing

Raluca Nicu, Diana Elena Ciolacu, Anca-Roxana Petrovici, Daniela Rusu, Mihaela Avadanei, Andreea Cristina Mihaila, Elena Butoi and Florin Ciolacu

IJMS, 2023, 24, 4213
DOI: 10.3390/ijms24044213

Gellan gum-dopamine mediated in situ synthesis of silver nanoparticles and development of nano/micro-composite injectable hydrogel with antimicrobial activity

Giuseppina Biscari, Michael Malkoch, Calogero Fiorica, Yanmiao Fan, Fabio Salvatore Palumbo, Serena Indelicato, David Bongiorno and Giovanna Pitarresi

International Journal of Biological Macromolecules, 2024, 258, 128766
DOI: 10.1016/j.ijbiomac.2023.128766

Chitosan-based composite film dressings with efficient self-diagnosis and synergistically inflammation resolution for accelerating diabetic wound healing

Can Li, Fei Chang, Fucheng Gao, Yandong Wang, Zhongqi Sun, Li Zhao, Yufei Yang, Haitao Wang, Lun Dong, Xiangrong Zheng and Yanyan Jiang

Applied Surface Science, 2024, 642, 158578
DOI: 10.1016/j.apsusc.2023.158578

An NIR-responsive “4A hydrogel” encapsulating wormwood essential oil: through antibacterial, antioxidant, anti-inflammation, and angiogenic to promote diabetic wound healing

Mengjuan Tao, Zhiwei Sun, Haiyan Wang, Na Meng, Xiangru Chen, Jianwei Mao, Heyan Huang, Yan Huang, Jin Liu, Zhenxing Wang, Weiqiang Tan, Yonggang Chen, Chuchao Zhou and Yanqing Yang

Materials Today Bio, 2025, 32, 101751
DOI: 10.1016/j.mtbio.2025.101751

Single-Component Starch-Based Hydrogels for Therapeutic Delivery

Alfio Pulvirenti, Antonella Caterina Boccia, Carolina Constantin, Mihaela Surcel, Adriana Munteanu, Victor-Eduard Peteu and Monica Neagu

Molecules, 2024, 29, 5463
DOI: 10.3390/molecules29225463

Double-Network Chitosan-Based Hydrogels with Improved Mechanical, Conductive, Antimicrobial, and Antibiofouling Properties

Rahela Carpa, Anca Farkas, Cristina Dobrota and Anca Butiuc-Keul

Gels, 2023, 9, 278
DOI: 10.3390/gels9040278

Development of phage-containing hydrogel for treating Enterococcus faecalis-infected wounds

Sahar Abed, Masoumeh Beig, Seyed Mahmoud Barzi, Morvarid Shafiei, Abdolrazagh Hashemi Shahraki, Sara Sadeghi, Aria Sohrabi and Abdelwahab Omri

PLoS ONE, 2024, 19, e0312469
DOI: 10.1371/journal.pone.0312469

Iron(III) cross-linked hydrogels based on Alteromonas macleodii Mo 169 exopolysaccharide

Patrícia Concórdio-Reis, Matilde Martins, Diana Araújo, Vítor D. Alves, Xavier Moppert, Jean Guézennec, Maria A.M. Reis and Filomena Freitas

International Journal of Biological Macromolecules, 2024, 274, 133312
DOI: 10.1016/j.ijbiomac.2024.133312

Tissue Regeneration with Gelatine/Polysaccharide Derived Hydrogel Scaffolds: From Formulation to In Vivo Efficacy

Jing Li, Keying He and Qian Xu

Gels, 2023, 9, 744
DOI: 10.3390/gels9090744

Unsaturated and thiolated derivatives of polysaccharides as functional matrixes for tissue engineering and pharmacology: A review

Ivan A. Farion, Vitalii F. Burdukovskii, Bato Ch. Kholkhoev and Peter S. Timashev

Carbohydrate Polymers, 2021, 259, 117735
DOI: 10.1016/j.carbpol.2021.117735

Recent developments of polysaccharide‐based double‐network hydrogels

Haodong Zhang, Ling Wa Eric Shi and Jinping Zhou

Journal of Polymer Science, 2023, 61, 7
DOI: 10.1002/pol.20220510

Polysaccharide-based hydrogels: New insights and futuristic prospects in wound healing

Neha Raina, Rakesh Pahwa, Vijay Kumar Thakur and Madhu Gupta

International Journal of Biological Macromolecules, 2022, 223, 1586
DOI: 10.1016/j.ijbiomac.2022.11.115

Oral absorption mechanisms of polysaccharides and potential as carriers for the construction of nano-delivery systems: A review

Bing Yang, Yan Xu, Weiye Zhang, Dandan Zhu, Bin Huang, Yanjun Yang, Xiaobin Jia and Liang Feng

International Journal of Biological Macromolecules, 2025, 310, 143184
DOI: 10.1016/j.ijbiomac.2025.143184

Functional Agarose Hydrogels Obtained by Employing Homogeneous Synthesis Strategies

Martin Gericke, Markus Witzler, Astrid Enkelmann, Gerlind Schneider, Margit Schulze and Thomas Heinze

Polysaccharides, 2024, 5, 184
DOI: 10.3390/polysaccharides5030014

Preparation and Characterization of Natural Silk Fibroin Hydrogel for Protein Drug Delivery

Junwei Liu, Haowen Sun, Yuwei Peng, Ligen Chen, Wei Xu and Rong Shao

Molecules, 2022, 27, 3418
DOI: 10.3390/molecules27113418

Cationic peptide-based salt-responsive antibacterial hydrogel dressings for wound healing

Jingfeng Yuan, Dong Zhang, Xiaomin He, Yifeng Ni, Lingbin Che, Jiang Wu, Baoyi Wu, Yang Wang, Shuguang Wang, Dongyong Sha, Si Yu Zheng and Jintao Yang

International Journal of Biological Macromolecules, 2021, 190, 754
DOI: 10.1016/j.ijbiomac.2021.09.019

Bacterial cellulose-based hydrogel with regulated rehydration and enhanced antibacterial activity for wound healing

Lili Deng, Fangzhou Li, Zhiliang Han, Xiangyang Qu, Jing Li, Zhou Zhou, Shiyan Chen, Huaping Wang and Xiangguo Lv

International Journal of Biological Macromolecules, 2024, 267, 131291
DOI: 10.1016/j.ijbiomac.2024.131291

β-Alanine enhancing the crosslink of chitosan/poly-(γ-glutamic acid) hydrogel for a potential alkaline-adapted wound dressing

Ziwei Hu, Dandan Liu, Mengmeng Wang, Chenrui Yu, Zhenxing Han, Maodong Xu, Wenjin Yue and Guangjun Nie

International Journal of Biological Macromolecules, 2023, 231, 123157
DOI: 10.1016/j.ijbiomac.2023.123157

An additive-free multifunctional β-glucan-peptide hydrogel participates in the whole process of bacterial-infected wound healing

Li Li, Yinglu Wang, Zhengjun Huang, Zuxian Xu, Ruipin Cao, Jiaxin Li, Biyi Wu, Jian Ren Lu and Hu Zhu

Journal of Controlled Release, 2023, 362, 577
DOI: 10.1016/j.jconrel.2023.09.010

Sustained release of magnesium and zinc ions synergistically accelerates wound healing

Fan Yang, Yijia Xue, Feilong Wang, Danni Guo, Yunjiao He, Xiao Zhao, Fanyu Yan, Yuqian Xu, Dandan Xia and Yunsong Liu

Bioactive Materials, 2023, 26, 88
DOI: 10.1016/j.bioactmat.2023.02.019

Wound Dressing Double-Crosslinked Quick Self-Healing Hydrogel Based on Carboxymethyl Chitosan and Modified Nanocellulose

Anshan Huang, Yehong Chen and Chaojun Wu

Polymers, 2023, 15, 3389
DOI: 10.3390/polym15163389

Self-Immolative Hydrogels with Stimulus-Mediated On–Off Degradation

Jue Gong, Aneta Borecki and Elizabeth R. Gillies

Biomacromolecules, 2023, 24, 3629
DOI: 10.1021/acs.biomac.3c00382

Hydrogel Formation of Enzymatically Solubilized Corn Bran Feruloylated Arabinoxylan by Laccase-Catalyzed Cross-Linking

Changxin Liu, Zifan Zhao, Weijie Zhong, Zilong Su, Qing Zhang, Yiqing Zhang, Shang Lin, Xuesong Lu and Wen Qin

Foods, 2025, 14, 2819
DOI: 10.3390/foods14162819

A Comprehensive Review on Bio-Based Materials for Chronic Diabetic Wounds

Jinjin Pei, Chella Perumal Palanisamy, Phaniendra Alugoju, Naga Venkata Anusha Anthikapalli, Prabhu Manickam Natarajan, Vidhya Rekha Umapathy, Bhuminathan Swamikannu, Selvaraj Jayaraman, Ponnulakshmi Rajagopal and Sirilux Poompradub

Molecules, 2023, 28, 604
DOI: 10.3390/molecules28020604

Injectable antibacterial drug-free hydrogel dressing enabled by a bioactive peptide-mimicking synthetic peptidyl polymer

Rong Zhang, Yongchang Tian, Jiaming Cui, Ian W Hamley, Chunsheng Xiao and Li Chen

Acta Biomaterialia, 2025, 193, 143
DOI: 10.1016/j.actbio.2025.01.008