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Challenges and opportunities of pharmaceutical cocrystals: a focused review on non-steroidal anti-inflammatory drugs

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A 5-fluorouracil–kaempferol drug–drug cocrystal: a ternary phase diagram, characterization and property evaluation

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Drug–drug salts of mefenamic acid\tolfenamic acid and piperazine to improve physicochemical properties for potential veterinary use

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Isostructural cocrystals of metaxalone with improved dissolution characteristics

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Drug–Drug Cocrystals Provide Significant Improvements of Drug Properties in Treatment with Progesterone

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Crystal Growth & Design, 2020, 20, 3053
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Complex methodology for rational design of Apremilast-benzoic acid co-crystallization process

Jan Jirát, Daniel Ondo, Martin Babor, Luděk Ridvan and Miroslav Šoóš

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Strategy to Tune the Performance of Two Drug Components: Drug–Drug Cocrystals of Lobaplatin with Flavonoids

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A COMPREHENSIVE REVIEW ON MULTI-DRUG COCRYSTALS

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Nevirapine Pharmaceutical Cocrystal: Design, Development and Formulation

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Analytical Methods for Determination of Apremilast from Bulk, Dosage Form and Biological Fluids: A Critical Review

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Two Cocrystals of Berberine Chloride with Myricetin and Dihydromyricetin: Crystal Structures, Characterization, and Antitumor Activities

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Molecular complexes of drug combinations: A review of cocrystals, salts, coamorphous systems and amorphous solid dispersions

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International Journal of Pharmaceutics, 2023, 648, 123555
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Drug-drug salts of Naftopidil with non-steroidal anti-inflammatory drugs for potential multi-drug therapy

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Understanding the formation of apremilast cocrystals

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Hydrotropy and co-crystallization for synergistic enhancement of dissolution rate and in vivo anti-inflammatory efficacy of ebastine

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Structural Features of Sulfamethizole and Its Cocrystals: Beauty Within

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First cocrystal of esculetin: Simultaneously optimized in vitro/vivo properties and antioxidant effect

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Co-processing of Atorvastatin and Ezetimibe for Enhanced Dissolution Rate: In Vitro and In Vivo Correlation

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The cocrystal structure of praziquantel-hesperetin (1/1), C35H38N2O8

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Development of Apremilast Solid Dispersion Using TPGS and PVPVA with Enhanced Solubility and Bioavailability

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Formation of Isostructural Solvate Forms of Apremilast from the View of Nucleation Behavior

Qi Zhang, Yizhen Yan, Ang Li, Yisheng Xu and Xiangyang Zhang

Crystal Growth & Design, 2025, 25, 6558
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In vitro-in silico evaluation of Apremilast solid dispersions prepared via Corotating Twin Screw Extruder

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Unlocking the potential of drug-drug cocrystals – A comprehensive review

Madhulika Banerjee, Kartik Nimkar, Shivraj Naik and Vandana Patravale

Journal of Controlled Release, 2022, 348, 456
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The First Cocrystal of Baloxavir Marboxil: Insight to the Impact of the Unique O–H···O Hydrogen Bond on Cocrystal Structure and Properties

He-Mei Yin, Xin-Yu Sun, Ping Xu, Shu-Long Liu and Fu-Min Xue

Crystal Growth & Design, 2026, 26, 2519
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Slow-Release Drug–Drug Cocrystals of Oxaliplatin with Flavonoids: Delaying Hydrolysis and Reducing Toxicity

He-Mei Yin, Nan Wu, Bi-Jian Zhou, Ming-Huang Hong, Bin Zhu, Ming-Hui Qi and Guo-Bin Ren

Crystal Growth & Design, 2021, 21, 75
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Formation of the First Non-Isostructural Cocrystal of Apremilast Explained

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Apremilast Cocrystals with Phenolic Coformers

Yelizaveta Naumkina, Bohumil Kratochvíl, Elena Korotkova and Jan Čejka

Molecules, 2024, 29, 6060
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Technical and Formulation Aspects of Pharmaceutical Co‐Crystallization: A Systematic Review

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New Chrysin-based co-crystals: Synthesis, characterization and dissolution studies

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Structural and Solubility Studies of Novel Salts and Cocrystals of the Antihistamine Drug Bilastine with Carboxylic Acid Derivatives

Sunil Kumar Nechipadappu and Debasish Swain

Crystal Growth & Design, 2022, 22, 2470
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Solid State Characterization and Dissolution Enhancement of Nevirapine Cocrystals

Prabhakar Panzade, Giridhar Shendarkar, Deepak Kulkarni and Santosh Shelke

Adv Pharm Bull, 2020, 11, 772
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Drug-drug cocrystals: Opportunities and challenges

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An analysis of multidrug multicomponent crystals as tools for drug development

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Cocrystal design of vanillin with amide drugs: Crystal structure determination, solubility enhancement, DFT calculation

Jinbo Ouyang, Xiaohong Xing, Limin Zhou, Chuntao Zhang and Jerry.Y.Y. Heng

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Systematic Development of Hot Melt Extrusion-Based Amorphous Solid Dispersion: Integrating Quality by Design and In Silico Modeling

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Crystal Structures, Stability, and Solubility Evaluation of a 2:1 Diosgenin–Piperazine Cocrystal

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Simultaneously improving the physicochemical and pharmacokinetic properties of vemurafenib through cocrystallization strategy

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Apremilast Amorphous Solid Dispersions: Formulation Optimization using QbD and Comprehensive In vitro-In silico Assessment

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Solid-state and particle size control of pharmaceutical cocrystals using atomization-based techniques

Aaron O'Sullivan, Barry Long, Vivek Verma, Kevin M. Ryan and Luis Padrela

International Journal of Pharmaceutics, 2022, 621, 121798
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Structure–property relations of a unique and systematic dataset of 19 isostructural multicomponent apremilast forms

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