An environmentally benign multi-component reaction: regioselective synthesis of fluorinated 2-aminopyridines using diverse properties of the nitro group

Xuan-Xuan Du, Quan-Xing Zi, Yu-Meng Wu, Yi Jin, Jun Lin and Sheng-Jiao Yan

Green Chem., 2019, 21, 1505
DOI: 10.1039/C8GC03698E

Alkali metal-ion assisted Michael addition reaction in controlled tailoring of topography in a superhydrophobic polymeric monolith

Adil M. Rather, Arpita Shome, Suresh Kumar, Bibhas K. Bhunia, Biman B. Mandal, Hemant Kumar Srivastava and Uttam Manna

J. Mater. Chem. A, 2018, 6, 17019
DOI: 10.1039/C8TA06329J

Facile access to N-formyl imide as an N-formylating agent for the direct synthesis of N-formamides, benzimidazoles and quinazolinones

Hsin-Yi Huang, Xiu-Yi Lin, Shih-Yao Yen and Chien-Fu Liang

Org. Biomol. Chem., 2020, 18, 5726
DOI: 10.1039/D0OB01080D

Green synthesis of new pyrrolidine-fused spirooxindoles via three-component domino reaction in EtOH/H2O

Yong-Chao Wang, Jun-Liang Wang, Kevin S. Burgess, Jiang-Wei Zhang, Qiu-Mei Zheng, Ya-Dan Pu, Li-Jun Yan and Xue-Bing Chen

RSC Adv., 2018, 8, 5702
DOI: 10.1039/C7RA13207G

One-pot three-component reaction of p-quinone monoacetals, l-proline and naphthols to afford N-aryl-2-arylpyrrolidines

Xin Wang, Gang Li, Xiaojie Li, Dunru Zhu and Ruwei Shen

Org. Chem. Front., 2021, 8, 297
DOI: 10.1039/D0QO01294G

Bridged rings from phenolic feedstocks: regio- and diastereoselective substitution-hemiketalization cyclization of bridged benzoxocin-4-ones with Grignard reagents

Xiaojie Li, Yishuai Fan, Haoran Yang and Ruwei Shen

Org. Chem. Front., 2025, 12, 1858
DOI: 10.1039/D4QO02197E

Chemistry of lignin and condensed tannins as aromatic biopolymers

Farzad Seidi, Yuqian Liu, Yang Huang, Huining Xiao and Daniel Crespy

Chem. Soc. Rev., 2025, 54, 3140
DOI: 10.1039/D4CS00440J

An environmentally benign cascade reaction of chromone-3-carboxaldehydes with ethyl 2-(pyridine-2-yl)acetate derivatives for highly site-selective synthesis of quinolizines and quinolizinium salts in water

Li Chen, Rong Huang, Kun Li, Xing-Han Yun, Chang-Long Yang and Sheng-Jiao Yan

Green Chem., 2020, 22, 6943
DOI: 10.1039/D0GC02460K

Zinc-catalyzed regioselective C–P coupling of p-quinol ethers with secondary phosphine oxides to afford 2-phosphinylphenols

Ming Zhang, Xiaoyu Jia, Haowei Zhu, Xutong Fang, Chenyi Ji, Sizhuo Zhao, Li-Biao Han and Ruwei Shen

Org. Biomol. Chem., 2019, 17, 2972
DOI: 10.1039/C9OB00129H

Cu(ii)-catalyzed annulation of α,β-unsaturated ketoxime acetates with 3-formylchromones for the synthesis of functionalized 2,4-diarylpyridines

Jing Yang, Xing-Mei Hu, Ke-Hua Zhao, Kun Huang and Sheng-Jiao Yan

New J. Chem., 2024, 48, 11682
DOI: 10.1039/D4NJ01648C

An Environmentally Benign Multicomponent Cascade Reaction of 3-Formylchromones, 2-Naphthols, and Heterocyclic Ketal Aminals: Site-Selective Synthesis of Functionalized Morphan Derivatives

Ying-Gang Duan, Yi-Hua Chen, Zi-Han Lu, Rong Huang and Sheng-Jiao Yan

J. Org. Chem., 2022, 87, 8562
DOI: 10.1021/acs.joc.2c00695

TBAI/K2S2O8‐Promoted Multicomponent Domino Reaction of Aryl Methyl Ketones, Enaminones, and Indoles: A Facile Access to Multisubstituted 3‐Indolyl‐pyrroles

Jiao Yang, Pan Zhou, Biao Hu, Siyun Zhao, Qiaohe Zhang, Li Xu, Rui Yang and Fuchao Yu

ChemistrySelect, 2018, 3, 11938
DOI: 10.1002/slct.201803317

An Environmentally Benign Cascade Reaction of 1,1-Enediamines (EDAMs) for Site-Selective Synthesis of Highly Functionalized 2,10-Dihydro-1H-imidazo[1′,2′:1,6]pyrido[2,3-b]indoles and Pyrroles

Cong-Hai Zhang, Rong Huang, Zhong-Wei Zhang, Jun Lin and Sheng-Jiao Yan

J. Org. Chem., 2021, 86, 5744
DOI: 10.1021/acs.joc.1c00211

Pyrrolidine‐Catalyzed Annulations of Quinone Monoacetals with Naphthols: Synthesis of 2‐Oxabicyclo[3.3.1]nonane Skeletons, Transformations and Reaction Mechanism

Xiaojie Li, Tianyu Xiao, Guangke He, Shugao Zhu, Dunru Zhu and Ruwei Shen

Adv Synth Catal, 2022, 364, 622
DOI: 10.1002/adsc.202101166

Intermolecular enantioselective dearomatizing para-methoxylation of phenols using 2-iodoresorcinol/lactamide catalysts

Karol Kraszewski, Ireneusz Tomczyk and Marcin Kalek

Tetrahedron Letters, 2022, 108, 154127
DOI: 10.1016/j.tetlet.2022.154127

Highly Stereoselective Synthesis of α-Oxoketene N,X-Acetals (X = O, S, or N) under Mild Conditions

Jia-Cheng Li, Jia-Wang Li, Rui Zhang and Dewen Dong

Org. Lett., 2025, 27, 1906
DOI: 10.1021/acs.orglett.5c00174

Two Complementary Cyclization Reactions for the Chemoselective Synthesis of Spirooxindoles

Pan Zhou, Biao Hu, Jiao Yang, Lingdan Li, Kairui Rao, Daofei Zhu and Fuchao Yu

Eur J Org Chem, 2017, 2017, 7256
DOI: 10.1002/ejoc.201701413

Diastereoselective Cascade Double Michael Addition to Access Bridged Coumarins, Oxindoles and Spirooxindoles: A Sustainable Strategy for Synthesis of Anticancer Molecules

Shravani Battula, Haripriya Bhumannagari, S. S. S. S. Sudha Ambadipudi, Sai Balaji Andugulapati and Kiranmai Nayani

ChemMedChem, 2025, 20
DOI: 10.1002/cmdc.202400946

Site-Selective Reaction of Enaminones and Enamine Esters for the Synthesis of Novel Diverse Morphan Derivatives

Xing-Mei Hu, Bei Zhou, Chang-Long Yang, Jun Lin and Sheng-Jiao Yan

ACS Omega, 2018, 3, 5994
DOI: 10.1021/acsomega.8b00726

An environmentally benign cascade reaction of 1,2,3-indantriones with ethyl 2-(pyridine-2-yl)acetates for site-selective synthesis of 5H-isochromeno[4,3-b]indolizin-5-ones

Haodan He, Jiahui Nie, Yinggang Duan, Jun Lin and Shengjiao Yan

Green Synthesis and Catalysis, 2021, 2, 54
DOI: 10.1016/j.gresc.2021.01.002

Anion cascade reactions III: Synthesis of 3-isoquinuclidone bridged polycyclic lactams

Zhiguo Zhang, Bingbing Shi, Xiyang Cao, Nana Ma, Hao Wu, Xingjie Zhang and Guisheng Zhang

Chinese Chemical Letters, 2024, 35, 109184
DOI: 10.1016/j.cclet.2023.109184

Bridged‐Ring Skeletons from Organoaluminium‐Mediated Nucleophilic Addition‐Cyclization Sequence of p‐Quinone Monoacetals and Grignard Reagents

Yishuai Fan, Kaixin Yin, Xiaojie Li, Jinzhe Huang and Ruwei Shen

Adv Synth Catal, 2023, 365, 3172
DOI: 10.1002/adsc.202300709

Base-promoted relay reaction of heterocyclic ketene aminals with o-difluorobenzene derivatives for the highly site-selective synthesis of functionalized indoles

Da-Yun Luo, Xing-Mei Hu, Rong Huang, Shi-Sheng Cui and Sheng-Jiao Yan

Tetrahedron, 2021, 92, 132275
DOI: 10.1016/j.tet.2021.132275

Synthesis of bridged bicyclic thiazine-2-thione and thiazole-2-thiones through DBU-promoted regioselective annulation of quinone monoacetals under mild conditions

Hong Qin, Man Yang, Yuguang Li, Xiaobing Yang, Yujing Hu, Chengkou Liu, Wei He, Zheng Fang and Kai Guo

Green Synthesis and Catalysis, 2025, 6, 399
DOI: 10.1016/j.gresc.2023.12.004

Multicomponent Cascade Reaction by Metal-Free Aerobic Oxidation for Synthesis of Highly Functionalized 2-Amino-4-coumarinyl-5-arylpyrroles

Quan-Xing Zi, Chang-Long Yang, Kun Li, Qin Luo, Jun Lin and Sheng-Jiao Yan

J. Org. Chem., 2020, 85, 327
DOI: 10.1021/acs.joc.9b02063

Highly selective synthesis of functionalized morphan derivatives through a multi-component cascade reaction of 3-formylchromones, 2-naphthols, and enaminones

Xinling Cao, Yinggang Duan, Kaihong Lv, Zihan Lu, Yihua Chen and Shengjiao Yan

Green Synthesis and Catalysis, 2023, 4, 321
DOI: 10.1016/j.gresc.2022.10.014

Substrate-Controlled Three-Component Synthesis of Diverse Fused Heterocycles

Anatoly A. Peshkov, Diana Gapanenok, Aleksandra Puzyk, Niyaz Amire, Alexander S. Novikov, Sofia D. Martynova, Stanislav Kalinin, Dmitry Dar’in, Vsevolod A. Peshkov and Mikhail Krasavin

J. Org. Chem., 2023, 88, 10508
DOI: 10.1021/acs.joc.3c00497

An Approach to One‐Pot Regioselective Synthesis of Indenones through Palladium‐Catalyzed Annulation in Water

Karu Ramesh and Gedu Satyanarayana

Eur J Org Chem, 2018, 2018, 4135
DOI: 10.1002/ejoc.201800591

Phosphatase CDC25B Inhibitors Produced by Basic Alumina-Supported One-Pot Gram-Scale Synthesis of Fluorinated 2-Alkylthio-4-aminoquinazolines Using Microwave Irradiation

Jin Liu, Yu-Ling Wang, Ji-Hong Zhang, Jian-Shan Yang, Han-Chuan Mou, Jun Lin and Sheng-Jiao Yan

ACS Omega, 2018, 3, 4534
DOI: 10.1021/acsomega.8b00640

Rational Chemical Engineering in Natural Protein Derived Functional Interface

Arpita Shome, Adil M. Rather, Aindrila Ghosal, Bibhas K. Bhunia, Biman B. Mandal and Uttam Manna

ACS Sustainable Chem. Eng., 2019, 7, 7502
DOI: 10.1021/acssuschemeng.9b00501

Three-Component Site-Selective Synthesis of Highly Substituted 5H-Chromeno-[4,3-b]pyridines

Cong-Hai Zhang, Rong Huang, Xing-Mei Hu, Jun Lin and Sheng-Jiao Yan

J. Org. Chem., 2018, 83, 4981
DOI: 10.1021/acs.joc.8b00099

Mn(OAc)3-Promoted Oxidative Csp3–P Bond Formation through Csp2–Csp2 and P–H Bond Cleavage: Access to β-Ketophosphonates

Pan Zhou, Biao Hu, Lingdan Li, Kairui Rao, Jiao Yang and Fuchao Yu

J. Org. Chem., 2017, 82, 13268
DOI: 10.1021/acs.joc.7b02391

An improved Pfitzinger reaction for the direct synthesis of quinoline-4-carboxylic esters/acids mediated by TMSCl

Pan Zhou, Biao Hu, Siyuan Zhao, Qiaohe Zhang, Yanqin Wang, Xiang Li and Fuchao Yu

Tetrahedron Letters, 2018, 59, 3116
DOI: 10.1016/j.tetlet.2018.07.006

Highly Selective Synthesis of 2-Amino-4,6-diarylpyridine Derivatives by the Cascade Reaction of 1,1-Enediamines with α,β-Unsaturated Ketones

Qin Luo, Rong Huang, Qiang Xiao, Yuan Yao, Jun Lin and Sheng-Jiao Yan

J. Org. Chem., 2019, 84, 1999
DOI: 10.1021/acs.joc.8b03008

Access to (Z)-1,2-Endiamides and 1,1-Endiamides via a Base-Promoted Tandem Reaction

Zhenming Zhang, Bei Fu, Hui Wang, Han Chen, Yongliang Tu and Junfeng Zhao

J. Org. Chem., 2020, 85, 5245
DOI: 10.1021/acs.joc.9b03305

Three-Component Cascade Reaction of 1,1-Enediamines, N,N-Dimethylformamide Dimethyl Acetal, and 1,3-Dicarbonyl Compounds: Selective Synthesis of Diverse 2-Aminopyridine Derivatives

Quan-Xing Zi, Sheng-Jiao Yan, Chang-Long Yang, Kun Li and Jun Lin

ACS Omega, 2019, 4, 2863
DOI: 10.1021/acsomega.8b03284

Organocatalytic Enantioselective Conia‐Ene‐Type Carbocyclization of Ynamide Cyclohexanones: Regiodivergent Synthesis of Morphans and Normorphans

Yin Xu, Qing Sun, Tong‐De Tan, Ming‐Yang Yang, Peng Yuan, Shao‐Qi Wu, Xin Lu, Xin Hong and Long‐Wu Ye

Angew Chem Int Ed, 2019, 58, 16252
DOI: 10.1002/anie.201908495

A Regioselective, One-Pot, Transition-Metal-Free α-Alkylation of Quinone Monoacetals for Various Organic Transformations

Pragya Sharma, Rahul Vishwakarma, Riya Rakheja, Sharda Pasricha and Chinmoy Kumar Hazra

Org. Lett., 2024, 26, 9682
DOI: 10.1021/acs.orglett.4c03430

Recent advances in the chemistry of two-carbon nitro-containing synthetic equivalents

D. N. Lyapustin, V. V. Fedotov, E. N. Ulomsky, V. L. Rusinov and O. N. Chupakhin

RUSS CHEM REV, 2023, 92, RCR5077
DOI: 10.57634/RCR5077

Solvent‐Switchable Regiodivergent Chlorination of Quinone Monoacetals: A Practical Route to 2‐ and 3‐Chlorophenols

Pragya Sharma, Sharda Pasricha, Sunny Singh, Mainak Dey and Chinmoy Kumar Hazra

Adv Synth Catal, 2026, 368
DOI: 10.1002/adsc.70234

Design, Synthesis, and Synergistic Activities of Eight‐Membered Carbon Bridged Neonicotinoid Derivatives

Du Tan, Xiaoyong Xu, Zhong Li, Zhiping Xu and Xusheng Shao

Chemistry & Biodiversity, 2024, 21
DOI: 10.1002/cbdv.202301412

Convenient Synthesis of Quinoline‐4‐carboxylate Derivatives through the Bi(OTf)3‐Catalyzed Domino Cyclization/Esterification Reaction of Isatins with Enaminones in Alcohols

Pan Zhou, Biao Hu, Yanqin Wang, Qiaohe Zhang, Xiang Li, Shengjiao Yan and Fuchao Yu

Eur J Org Chem, 2018, 2018, 4527
DOI: 10.1002/ejoc.201800734

Multicomponent Synthesis of Diversified Chromeno[3,2-d]oxazoles

Parisa Zamani, Joshua Phipps, Jiyun Hu, Faizan Cheema, Hadi Amiri Rudbari, Abdol-Khalegh Bordbar, Ahmad R. Khosropour and Hudson Beyzavi

ACS Comb. Sci., 2019, 21, 557
DOI: 10.1021/acscombsci.9b00084

An environmentally benign multi-component reaction: Highly regioselective synthesis of functionalized 2-(diarylphosphoryl)-1,2-dihydro-pyridine derivatives

Kun Li, Ying Lv, Zihan Lu, Xinghan Yun and Shengjiao Yan

Green Synthesis and Catalysis, 2022, 3, 59
DOI: 10.1016/j.gresc.2021.10.008

Direct Access to α-Oxoketene Aminals via Copper-Catalyzed Formal Oxyaminalization of Alkenes under Mild Conditions

Lu Wang, Chaorong Qi, Tianzuo Guo and Huanfeng Jiang

Org. Lett., 2019, 21, 2223
DOI: 10.1021/acs.orglett.9b00518

Anion Cascade Reactions II: Synthesis of 3-Isoquinuclidone-Based Bridged Polycyclic Lactams

Bingbing Shi, Zhiguo Zhang, Xiyang Cao, Nana Ma, Shujun Li, Hao Wu, Xingjie Zhang and Guisheng Zhang

Org. Lett., 2023, 25, 6846
DOI: 10.1021/acs.orglett.3c02356

Iridium/Acid Dual-Catalyzed Enantioselective Aza-ene-type Allylic Alkylation of Nitro Ketene Aminals with Racemic Allylic Alcohols

Diancong Chen, Man Zhang, Dongxu Zhang, Ziqi Zhang, Xusheng Shao, Xiaoyong Xu, Zhong Li and Wu-Lin Yang

Org. Lett., 2024, 26, 508
DOI: 10.1021/acs.orglett.3c03939

Substrate-Tuned Domino Annulation for Selective Synthesis of Poly-substituted Benzo[f]imidazo[2,1-a][2,7]naphthyridines and 3-Azaheterocyclic Substituted 2-Arylquinolines

Zhimin Ying, Jie Cen, Feng Luo, You Wu, Shuangrong Liu, Wenteng Chen, Jiaan Shao and Yongping Yu

J. Org. Chem., 2021, 86, 4747
DOI: 10.1021/acs.joc.1c00112

Iron-Catalyzed Reductive Ring-Rearrangement Reaction of Bridged Benzo[b]oxocin-4-ones with Grignard Reagents to Afford Bridged Benzo[b]oxocin-2-ols

Yishuai Fan, Haoran Yang, Ri Peng, Dunru Zhu and Ruwei Shen

Org. Lett., 2025, 27, 2693
DOI: 10.1021/acs.orglett.5c00451

Cascade Reactions Utilizing the Nucleophilic Properties of 1,1‐Enediamines for the Regioselective Synthesis of 4‐Aryl‐2‐aminopyridines

Ling‐Bin Kong, Sheng‐Jiao Yan, Yuan Yao, Qiang Xiao and Jun Lin

ChemistrySelect, 2019, 4, 3083
DOI: 10.1002/slct.201900026

Cu(II)/Iodine(III) Oxide Dimerization of Heterocyclic Ketene Aminals: Tandem TEMPO Oxidation for the Highly Selective Synthesis of Functionalized 2H-Pyrrolo[1,2-a]imidazol-7(3H)-ones

Kun Li, Rong Huang, Li Chen, Ying Lv and Sheng-Jiao Yan

Org. Lett., 2020, 22, 8210
DOI: 10.1021/acs.orglett.0c02689

Transition metal-catalyzed carboxylation of olefins with Carbon dioxide: a comprehensive review

Sandhya Saini, Pankaj Kumar Prajapati and Suman L Jain

Catalysis Reviews, 2022, 64, 631
DOI: 10.1080/01614940.2020.1831757

Diastereoselective Synthesis of Morphan Derivatives by Michael and Hetero-Michael Addition of 1,1-Enediamines to Quinone Monoketals

Xing-Mei Hu, Da-Yun Luo, Quan-Xing Zi, Jun Lin and Sheng-Jiao Yan

ACS Omega, 2018, 3, 8
DOI: 10.1021/acsomega.7b01493

Molecular Complexity from Aromatics: Recent Advances in the Chemistry of paraQuinol and Masked para‐Quinone Monoketal

Girish Chandra and Samridhi Patel

ChemistrySelect, 2020, 5, 12885
DOI: 10.1002/slct.202003802

Copper-catalyzed direct oxidative C(sp 2 )-H α -sulfenylation of enaminones with disulfides or thiophenols: Synthesis of polyfunctionalized aminothioalkenes

Biao Hu, Pan Zhou, Kairui Rao, Jiao Yang, Lingdan Li, Shengjiao Yan and Fuchao Yu

Tetrahedron Letters, 2018, 59, 1438
DOI: 10.1016/j.tetlet.2018.02.079

An eco-friendly electrochemical process for the formation of a new desloratadine derivative and its antibacterial susceptibility. Report of a new type of ortho-quinhydrone complex

Faezeh Zivari-Moshfegh and Davood Nematollahi

Electrochimica Acta, 2022, 421, 140518
DOI: 10.1016/j.electacta.2022.140518

Organocatalytic Enantioselective Conia‐Ene‐Type Carbocyclization of Ynamide Cyclohexanones: Regiodivergent Synthesis of Morphans and Normorphans

Yin Xu, Qing Sun, Tong‐De Tan, Ming‐Yang Yang, Peng Yuan, Shao‐Qi Wu, Xin Lu, Xin Hong and Long‐Wu Ye

Angewandte Chemie, 2019, 131, 16398
DOI: 10.1002/ange.201908495

Cascade Reaction of Isatins with 1,1-Enediamines: Synthesis of Multisubstituted Quinoline-4-carboxamides

Bao-Qu Wang, Cong-Hai Zhang, Xiao-Xue Tian, Jun Lin and Sheng-Jiao Yan

Org. Lett., 2018, 20, 660
DOI: 10.1021/acs.orglett.7b03803

Facile Route to the Synthesis of 1,3-Diazahetero-Cycle-Fused [1,2-a]Quinoline Derivatives via Cascade Reactions

Liang Chen, Rong Huang, Ling-Bin Kong, Jun Lin and Sheng-Jiao Yan

ACS Omega, 2018, 3, 1126
DOI: 10.1021/acsomega.7b01856

Cascade Reaction of 1,1-Enediamines with 2-Benzylidene-1H-indene-1,3(2H)-diones: Selective Synthesis of Indenodihydropyridine and Indenopyridine Compounds

Qin Luo, Rong Huang, Qiang Xiao, Ling-Bin Kong, Jun Lin and Sheng-Jiao Yan

ACS Omega, 2019, 4, 6637
DOI: 10.1021/acsomega.9b00407