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Confining enzymes in porous organic frameworks: from synthetic strategy and characterization to healthcare applications

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Biomimetic catalysis of metal–organic frameworks

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Glucose oxidase-mediated tumor starvation therapy combined with photothermal therapy for colon cancer

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Glucose oxidase and Au nanocluster co-encapsulated metal–organic frameworks as a sensitive colorimetric sensor for glucose based on a cascade reaction

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Combined Fenton and starvation therapies using hemoglobin and glucose oxidase

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Cascade amplified colorimetric immunoassay based on an integrated multifunctional composite with catalytic coordination polymers for prostate specific antigen detection

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Exploring enzyme-immobilized MOFs and their application potential: biosensing, biocatalysis, targeted drug delivery and cancer therapy

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Palladium NPs supported on sulfonic acid functionalized metal–organic frameworks as catalysts for biomass cascade reactions

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A biomimetic MOF nanoreactor enables synergistic suppression of intracellular defense systems for augmented tumor ablation

Peng Gao, Mingwan Shi, Ruyue Wei, Wei Pan, Xiaohan Liu, Na Li and Bo Tang

Chem. Commun., 2020, 56, 924
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Enzyme–MOF (metal–organic framework) composites

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Review on recent progress in metal–organic framework-based materials for fabricating electrochemical glucose sensors

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Preparation and characterization of a Combi-CLEAs from pectinases and cellulases: a potential biocatalyst for grape juice clarification

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Poly(ethylene glycol)-mediated mineralization of metal–organic frameworks

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Recent advances in biomolecule immobilization based on self-assembly: organic–inorganic hybrid nanoflowers and metal–organic frameworks as novel substrates

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Incorporation of enzyme-mimic species in porous materials for the construction of porous biomimetic catalysts

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Enzyme encapsulation in metal–organic frameworks for applications in catalysis

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CrystEngComm, 2017, 19, 4082
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Phase dependent encapsulation and release profile of ZIF-based biocomposites

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Fast multipoint immobilization of lipase through chirall-proline on a MOF as a chiral bioreactor

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Co-immobilization of a bi-enzymatic cascade into hierarchically porous MIL-53 for efficient 6′-sialyllactose production

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Cell-free biology using remote-controlled digital microfluidics for individual droplet control

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Green Chem., 2021, 23, 2362
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Preparation of light core/shell magnetic composite microspheres and their application for lipase immobilization

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Construction of robust bienzyme-mimicking nanocatalysts for dye degradation by self-assembly of hematin, metal ions, and nucleotides

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A POM-based copper-coordination polymer crystal material for phenolic compound degradation by immobilizing horseradish peroxidase

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Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy

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Lanthanide/nucleotide coordination polymers: an excellent host platform for encapsulating enzymes and fluorescent nanoparticles to enhance ratiometric sensing

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Immobilized enzymes in inorganic hybrid nanoflowers for biocatalytic and biosensing applications

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Enzyme entrapment, biocatalyst immobilization without covalent attachment

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Sheltering proteins from protease-mediated degradation and a de novo strategy for preventing acute liver injury

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Preparation of functionalized star polymer nanoparticles by RAFT polymerization and their application in positionally assembled enzymes for cascade reactions

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An acid-responsive all-in-one signal amplification strategy for the ultrasensitive prostate-specific antigen detection

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Coupling two enzymes into a tandem nanoreactor utilizing a hierarchically structured MOF

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Aqueous core and hollow silica nanocapsules for confined enzyme modules

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Template-free and room temperature synthesis of hierarchical porous zeolitic imidazolate framework nanoparticles and their dye and CO2sorption

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Synthesis and characterization of thermoresponsive ZIF-8@PNIPAm-co-MAA microgel composites with enhanced performance as an adsorption/release platform

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MOF nanozymes: active sites and sensing applications

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Enhanced stability and reusability of recombinant silicatein upon biomimetic metal–organic framework crystallization

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One-pot synthesis of a metal–organic framework-based drug carrier for intelligent glucose-responsive insulin delivery

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Multifunctional magnetic particles for effective suppression of non-specific adsorption and coimmobilization of multiple enzymes by DNA directed immobilization

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Degradation of ZIF-8 in phosphate buffered saline media

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Facile preparation of MOF-derived MHCo3O4&Co/C with a hierarchical porous structure for entrapping enzymes: having both high stability and catalytic activity

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An integrated nanocatalyst combining enzymatic and metal–organic framework catalysts for cascade degradation of organophosphate nerve agents

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Boosting multi-enzyme cascade activity for glucose biosynthesis by kinetics-oriented grouped immobilization

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Magnetic metal–organic frameworks as scaffolds for spatial co-location and positional assembly of multi-enzyme systems enabling enhanced cascade biocatalysis

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