Determination of spectral markers of cytotoxicity and genotoxicity using in vitro Raman microspectroscopy: cellular responses to polyamidoamine dendrimer exposure

Esen Efeoglu, Alan Casey and Hugh J. Byrne

Analyst, 2017, 142, 3848
DOI: 10.1039/C7AN00969K

In vitro monitoring of time and dose dependent cytotoxicity of aminated nanoparticles using Raman spectroscopy

Esen Efeoglu, Alan Casey and Hugh J. Byrne

Analyst, 2016, 141, 5417
DOI: 10.1039/C6AN01199C

Evaluation of non-invasive toxicological analysis of nano-polystyrene in relativein vivoconditions toD. magna

A. Reynolds, M. Giltrap and G. Chambers

Environ. Sci.: Nano, 2019, 6, 2832
DOI: 10.1039/C9EN00434C

Strategies for robust and accurate experimental approaches to quantify nanomaterial bioaccumulation across a broad range of organisms

Elijah J. Petersen, Monika Mortimer, Robert M. Burgess, Richard Handy, Shannon Hanna, Kay T. Ho, Monique Johnson, Susana Loureiro, Henriette Selck, Janeck J. Scott-Fordsmand, David Spurgeon, Jason Unrine, Nico W. van den Brink, Ying Wang, Jason White and Patricia Holden

Environ. Sci.: Nano, 2019, 6, 1619
DOI: 10.1039/C8EN01378K

Label-free, high content screening using Raman microspectroscopy: the toxicological response of different cell lines to amine-modified polystyrene nanoparticles (PS-NH2)

Esen Efeoglu, Marcus A. Maher, Alan Casey and Hugh J. Byrne

Analyst, 2017, 142, 3500
DOI: 10.1039/C7AN00461C

Spectralomics – Towards a holistic adaptation of label free spectroscopy

Hugh J. Byrne

Vibrational Spectroscopy, 2024, 132, 103671
DOI: 10.1016/j.vibspec.2024.103671

Data mining Raman microspectroscopic responses of cells to drugs in vitro using multivariate curve resolution-alternating least squares

David Perez-Guaita, Guillermo Quintas, Zeineb Farhane, Roma Tauler and Hugh J. Byrne

Talanta, 2020, 208, 120386
DOI: 10.1016/j.talanta.2019.120386

Advancing Raman microspectroscopy for cellular and subcellular analysis: towards in vitro high-content spectralomic analysis

Hugh J. Byrne, Franck Bonnier, Alan Casey, Marcus Maher, Jennifer McIntyre, Esen Efeoglu and Zeineb Farhane

Appl. Opt., 2018, 57, E11
DOI: 10.1364/AO.57.000E11

Raman microspectroscopy as a useful tool for nanopathology

Kristina Čabanová, Pavlína Peikertová, Hana Bielniková, Hana Barošová, Oldřich Motyka, Lenka Čábalová, Jana Dvořáčková, Pavel Komínek and Jana Kukutschová

J Raman Spectroscopy, 2017, 48, 357
DOI: 10.1002/jrs.5045

Quantification of Polystyrene Uptake by Different Cell Lines Using Fluorescence Microscopy and Label-Free Visualization of Intracellular Polystyrene Particles by Raman Microspectroscopic Imaging

Amelie Roth, Astrid Tannert, Nadja Ziller, Simone Eiserloh, Bianca Göhrig, Rustam R. Guliev, María José Gonzalez Vazquez, Max Naumann, Alexander S. Mosig, Sven Stengel, Astrid R. R. Heutelbeck and Ute Neugebauer

Cells, 2024, 13, 454
DOI: 10.3390/cells13050454

Nanoparticles based on polyferylic and polygentisic acids as new carriers of anticancer drugs

I. V. Smirnov, A. V. Lisov, A. S. Kazakov, A. N. Zvonarev, N. E. Suzina and M. Y. Zemskova

RUBI, 2024, 50
DOI: 10.31857/S0132342324020024

Combining Pharmacokinetics and Vibrational Spectroscopy: MCR-ALS Hard-and-Soft Modelling of Drug Uptake In Vitro Using Tailored Kinetic Constraints

David Pérez-Guaita, Guillermo Quintás, Zeineb Farhane, Romá Tauler and Hugh J. Byrne

Cells, 2022, 11, 1555
DOI: 10.3390/cells11091555

Cell‐Nanoparticle Interactions at (Sub)–Nanometer Resolution Analyzed by Electron Microscopy and Correlative Coherent Anti‐Stokes Raman Scattering

Jukka Saarinen, Friederike Gütter, Mervi Lindman, Mikael Agopov, Sara J. Fraser‐Miller, Regina Scherließ, Eija Jokitalo, Hélder A. Santos, Leena Peltonen, Antti Isomäki and Clare J. Strachan

Biotechnology Journal, 2019, 14
DOI: 10.1002/biot.201800413

In vitrolocalisation and degradation of few-layer MoS2submicrometric plates in human macrophage-like cells: a label free Raman micro-spectroscopic study

Caroline Moore, Andrew Harvey, Jonathan N Coleman, Hugh J Byrne and Jennifer McIntyre

2D Mater., 2020, 7, 025003
DOI: 10.1088/2053-1583/ab5d98

Toxicity mitigation and biodistribution of albumin corona coated graphene oxide and carbon nanotubes in Caenorhabditis elegans

Francine Côa, Fabrício de Souza Delite, Mathias Strauss and Diego Stéfani Teodoro Martinez

NanoImpact, 2022, 27, 100413
DOI: 10.1016/j.impact.2022.100413

Engineered Polymeric Materials for Biological Applications: Overcoming Challenges of the Bio–Nano Interface

Joshua D Simpson, Samuel A Smith, Kristofer J. Thurecht and Georgina Such

Polymers, 2019, 11, 1441
DOI: 10.3390/polym11091441

Label-free screening of biochemical changes in macrophage-like cells following MoS2 exposure using Raman micro-spectroscopy

Caroline Moore, Andrew Harvey, Jonathan N. Coleman, Hugh J. Byrne and Jennifer McIntyre

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 246, 118916
DOI: 10.1016/j.saa.2020.118916

Nanoparticles Based on Polyferulic and Polygentisic Acids as New Carriers of Anticancer Drugs

I. V. Smirnov, A. V. Lisov, A. N. Zvonarev, N. E. Suzina, A. S. Kazakov and M. Y. Zemskova

Russ J Bioorg Chem, 2024, 50, 467
DOI: 10.1134/S1068162024020213

Mapping Selenium Nanoparticles Distribution Inside Cells through Confocal Raman Microspectroscopy

Davide Redolfi-Bristol, Kenta Yamamoto, Wenliang Zhu, Osam Mazda, Pietro Riello, Elia Marin and Giuseppe Pezzotti

ACS Appl. Mater. Interfaces, 2025, 17, 18124
DOI: 10.1021/acsami.5c00380

Prediction of viral loads for diagnosis of Hepatitis C infection in human plasma samples using Raman spectroscopy coupled with partial least squares regression analysis

H. Nawaz, N. Rashid, M. Saleem, M. Asif Hanif, M. Irfan Majeed, I. Amin, M. Iqbal, M. Rahman, Ola Ibrahim, S. M. Baig, M. Ahmed, F. Bonnier and H. J. Byrne

J Raman Spectroscopy, 2017, 48, 697
DOI: 10.1002/jrs.5108

Monitoring and modelling the dynamics of the cellular glycolysis pathway: A review and future perspectives

Nitin Patil, Orla Howe, Paul Cahill and Hugh J. Byrne

Molecular Metabolism, 2022, 66, 101635
DOI: 10.1016/j.molmet.2022.101635

A multivariate statistical investigation of background subtraction algorithms for Raman spectra of cytology samples recorded on glass slides

L.T. Kerr and B.M. Hennelly

Chemometrics and Intelligent Laboratory Systems, 2016, 158, 61
DOI: 10.1016/j.chemolab.2016.08.012

Using intracellular plasmonics to characterize nanomorphology in human cells

Ahmad Sohrabi Kashani, Alisa Piekny and Muthukumaran Packirisamy

Microsyst Nanoeng, 2020, 6
DOI: 10.1038/s41378-020-00219-w

Nanotechnology-Assisted Cell Tracking

Alessia Peserico, Chiara Di Berardino, Valentina Russo, Giulia Capacchietti, Oriana Di Giacinto, Angelo Canciello, Chiara Camerano Spelta Rapini and Barbara Barboni

Nanomaterials, 2022, 12, 1414
DOI: 10.3390/nano12091414

Toxicological assessment of nanomaterials: the role of in vitro Raman microspectroscopic analysis

Esen Efeoglu, Marcus A. Maher, Alan Casey and Hugh J. Byrne

Anal Bioanal Chem, 2018, 410, 1631
DOI: 10.1007/s00216-017-0812-x

Screening the low molecular weight fraction of human serum using ATR-IR spectroscopy

Franck Bonnier, Guillaume Brachet, Romain Duong, Tobiloba Sojinrin, Renaud Respaud, Nicolas Aubrey, Matthew J. Baker, Hugh J. Byrne and Igor Chourpa

J. Biophoton, 2016, 9, 1085
DOI: 10.1002/jbio.201600015

Graphene Nanoflake Uptake Mediated by Scavenger Receptors

Fatima Alnasser, Valentina Castagnola, Luca Boselli, Margarita Esquivel-Gaon, Esen Efeoglu, Jennifer McIntyre, Hugh J. Byrne and Kenneth A. Dawson

Nano Lett., 2019, 19, 1260
DOI: 10.1021/acs.nanolett.8b04820

In vitro Label Free Raman Microspectroscopic Analysis to Monitor the Uptake, Fate and Impacts of Nanoparticle Based Materials

Hugh J. Byrne, Franck Bonnier, Esen Efeoglu, Caroline Moore and Jennifer McIntyre

Front. Bioeng. Biotechnol., 2020, 8
DOI: 10.3389/fbioe.2020.544311

Seeding multivariate algorithms for spectral analysis, a data augmentation approach to enhance analytical performance

M.E. Keating and H.J. Byrne

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 340, 126369
DOI: 10.1016/j.saa.2025.126369