Microfluidic screening of antibiotic susceptibility at a single-cell level shows the inoculum effect of cefotaxime on E. coli

Witold Postek, Pawel Gargulinski, Ott Scheler, Tomasz S. Kaminski and Piotr Garstecki

Lab Chip, 2018, 18, 3668
DOI: 10.1039/C8LC00916C

Highly flexible and accurate serial picoinjection in droplets by combined pressure and flow rate control

Jolien Breukers, Hannah Op de Beeck, Iene Rutten, Montserrat López Fernández, Sven Eyckerman and Jeroen Lammertyn

Lab Chip, 2022, 22, 3475
DOI: 10.1039/D2LC00368F

Microfluidic flow cytometry for blood-based biomarker analysis

Yuxin Zhang, Ying Zhao, Tim Cole, Jiahao Zheng, Bayinqiaoge, Jinhong Guo and Shi-Yang Tang

Analyst, 2022, 147, 2895
DOI: 10.1039/D2AN00283C

A highly addressable static droplet array enabling digital control of a single droplet at pico-volume resolution

Heon-Ho Jeong, Byungjin Lee, Si Hyung Jin, Seong-Geun Jeong and Chang-Soo Lee

Lab Chip, 2016, 16, 1698
DOI: 10.1039/C6LC00212A

Liquid-capped encoded microcapsules for multiplex assays

Younghoon Song, Yunjin Jeong, Taehong Kwon, Daewon Lee, Dong Yoon Oh, Tae-Joon Park, Junhoi Kim, Jiyun Kim and Sunghoon Kwon

Lab Chip, 2017, 17, 429
DOI: 10.1039/C6LC01268J

Biosensors and bioassays for determination of matrix metalloproteinases: state of the art and recent advances

Zhen Lei, Minghong Jian, Xiaotong Li, Jia Wei, Xianying Meng and Zhenxin Wang

J. Mater. Chem. B, 2020, 8, 3261
DOI: 10.1039/C9TB02189B

Programmable Control of Multiscale Droplets using V‐Valves

Tian Xue, Ankit Jain, Xiaobao Cao, David Hess, Stavros Stavrakis and Andrew de Mello

Adv Materials Technologies, 2023, 8
DOI: 10.1002/admt.202201553

Enhancing Throughput of Combinatorial Droplet Devices via Droplet Bifurcation, Parallelized Droplet Fusion, and Parallelized Detection

Kuangwen Hsieh, Helena Zec, Polly Ma, Tushar Rane and Tza-Huei Wang

Micromachines, 2015, 6, 1490
DOI: 10.3390/mi6101434

Single cell multiplexed assay for proteolytic activity using droplet microfluidics

Ee Xien Ng, Miles A. Miller, Tengyang Jing and Chia-Hung Chen

Biosensors and Bioelectronics, 2016, 81, 408
DOI: 10.1016/j.bios.2016.03.002

Manipulating the duration of picoinjection controls the injected volume of individual droplets

R. Thakur and D. Weitz

Biomicrofluidics, 2024, 18
DOI: 10.1063/5.0206830

Droplet Microfluidics for High-Throughput Screening and Directed Evolution of Biomolecules

Goran Vladisavljević

Micromachines, 2024, 15, 971
DOI: 10.3390/mi15080971

An acoustofluidic picoinjector

Ty Naquin, Shivam Jain, Jinxin Zhang, Xianchen Xu, Gary Yao, Chloe M. Naquin, Shujie Yang, Jianping Xia, Janna Wang, Sebastian Jimenez and Tony Jun Huang

Sensors and Actuators B: Chemical, 2024, 418, 136294
DOI: 10.1016/j.snb.2024.136294

Development of a simple static microwell array with uniform cell seeding and a chemical concentration gradient

S. I. Yeh, C. C. Hau, C. J. Huang, H. C. Chang, C. H. Hsu and J. T. Yang

Microfluid Nanofluid, 2017, 21
DOI: 10.1007/s10404-017-1921-8

Single Cell Analysis of Leukocyte Protease Activity Using Integrated Continuous-Flow Microfluidics

Tengyang Jing, Zhangxing Lai, Lidan Wu, Jongyoon Han, Chwee Teck Lim and Chia-Hung Chen

Anal. Chem., 2016, 88, 11750
DOI: 10.1021/acs.analchem.6b03370

Xiurui Zhu, Shisheng Su, Mingzhu Fu, Junyuan Liu, Lingxiang Zhu, Wenjun Yang, Gaoshan Jing and Yong Guo

Sci Rep, 2018, 8
DOI: 10.1038/s41598-018-28270-8

Tunable and Contamination-Free Injection with Microfluidics by Stepinjection

Beiyu Hu, Shun Ye, Dongwei Chen, Bingliang Xie, Ran Hu, Yuxin Qiao, Yanghuan Yu, Haiyan Yu, Xu Zheng, Ying Lan and Wenbin Du

Anal. Chem., 2021, 93, 13112
DOI: 10.1021/acs.analchem.1c02721

Passive Picoinjection Enables Controlled Crystallization in a Droplet Microfluidic Device

Shunbo Li, Muling Zeng, Thembaninkosi Gaule, Michael J. McPherson and Fiona C. Meldrum

Small, 2017, 13
DOI: 10.1002/smll.201702154

Detection of Enzyme Inhibitors in Crude Natural Extracts Using Droplet-Based Microfluidics Coupled to HPLC

Abraham Ochoa, Enrique Álvarez-Bohórquez, Eduardo Castillero and Luis F. Olguin

Anal. Chem., 2017, 89, 4889
DOI: 10.1021/acs.analchem.6b04988

The Tumor Proteolytic Landscape: A Challenging Frontier in Cancer Diagnosis and Therapy

Matej Vizovisek, Dragana Ristanovic, Stefano Menghini, Michael G. Christiansen and Simone Schuerle

IJMS, 2021, 22, 2514
DOI: 10.3390/ijms22052514

Functional Stem Cell Sorting via Integrative Droplet Synchronization

Guoyun Sun, Yao Teng, Zixuan Zhao, Lih Feng Cheow, Hanry Yu and Chia-Hung Chen

Anal. Chem., 2020, 92, 7915
DOI: 10.1021/acs.analchem.0c01312

Microfluidic microscopy-assisted label-free approach for cancer screening: automated microfluidic cytology for cancer screening

Veerendra Kalyan Jagannadh, G. Gopakumar, Gorthi R. K. Sai Subrahmanyam and Sai Siva Gorthi

Med Biol Eng Comput, 2017, 55, 711
DOI: 10.1007/s11517-016-1549-y

An acoustofluidic embedding platform for rapid multiphase microparticle injection

Ruoyu Zhong, Xianchen Xu, Gianna Tutoni, Mingyuan Liu, Kaichun Yang, Ke Li, Ke Jin, Ying Chen, John D. H. Mai, Matthew L. Becker and Tony Jun Huang

Nat Commun, 2025, 16
DOI: 10.1038/s41467-025-59146-x

A multiplexable microfluidic injector for versatile encoding of droplets

Johnson Q. Cui, Binbin Cui, Frank X. Liu, Yuan Lin and Shuhuai Yao

Sensors and Actuators B: Chemical, 2022, 371, 132573
DOI: 10.1016/j.snb.2022.132573

Droplet acoustofluidics: Recent progress and challenges

Mushtaq Ali, Woohyuk Kim, Muhammad Soban Khan, Mehmet Akif Sahin, Ghulam Destgeer and Jinsoo Park

Biomicrofluidics, 2025, 19
DOI: 10.1063/5.0261531

Directed evolution of diacetylchitobiose deacetylase via high-throughput droplet sorting with a novel, bacteria-based biosensor

Guoyun Sun, Yaokang Wu, Ziyang Huang, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv and Long Liu

Biosensors and Bioelectronics, 2023, 219, 114818
DOI: 10.1016/j.bios.2022.114818

Microfluidic Tools for Bottom-Up Synthetic Cellularity

Martina Ugrinic, Andrew deMello and T.-Y. Dora Tang

Chem, 2019, 5, 1727
DOI: 10.1016/j.chempr.2019.03.012

Color-Coded Droplets and Microscopic Image Analysis for Multiplexed Antibiotic Susceptibility Testing

Yunjin Jeong, Haewook Jang, Junwon Kang, Juhong Nam, Kyoungseob Shin, Sunghoon Kwon and Jungil Choi

Biosensors, 2021, 11, 283
DOI: 10.3390/bios11080283

An improved fluorescent substrate for assaying soluble and membrane-associated ADAM family member activities

Marcia L. Moss, Dmitriy Minond, Toshie Yoneyama, Hinrich P. Hansen, Nikola Vujanovic and Fred H. Rasmussen

Analytical Biochemistry, 2016, 507, 13
DOI: 10.1016/j.ab.2016.05.001

Electrochemical impedance spectroscopy for quantization of matrix Metalloproteinase-14 based on peptides inhibiting its homodimerization and heterodimerization

Fen Ma, Jiedong Yan, Lina Sun and Yu Chen

Talanta, 2019, 205, 120142
DOI: 10.1016/j.talanta.2019.120142

From specialization to broad adoption: Key trends in droplet microfluidic innovations enhancing accessibility to non-experts

Jolien Breukers, Karen Ven, Wannes Verbist, Iene Rutten and Jeroen Lammertyn

Biomicrofluidics, 2025, 19
DOI: 10.1063/5.0242599

Hydrogel-Framed Nanofiber Matrix Integrated with a Microfluidic Device for Fluorescence Detection of Matrix Metalloproteinases-9

Sang Won Han and Won-Gun Koh

Anal. Chem., 2016, 88, 6247
DOI: 10.1021/acs.analchem.5b04867

Highly Efficient Real-Time Droplet Analysis Platform for High-Throughput Interrogation of DNA Sequences by Melt

Christine M. O’Keefe, Aniruddha M. Kaushik and Tza-Huei Wang

Anal. Chem., 2019, 91, 11275
DOI: 10.1021/acs.analchem.9b02346

Droplet microfluidics for high‐sensitivity and high‐throughput detection and screening of disease biomarkers

Aniruddha M. Kaushik, Kuangwen Hsieh and Tza‐Huei Wang

WIREs Nanomed Nanobiotechnol, 2018, 10
DOI: 10.1002/wnan.1522