Looking at new ligands for chelation therapy

Valeria Marina Nurchi, Maria de Guadalupe Jaraquemada-Pelaez, Joanna I. Lachowicz, Maria Antonietta Zoroddu, Massimiliano Peana, Alicia Domínguez-Martín, Duane Choquesillo-Lazarte, Maurizio Remelli, Zbigniew Szewczuk and Guido Crisponi

New J. Chem., 2018, 42, 8021
DOI: 10.1039/C7NJ03947F

para-Aminosalicylic acid in the treatment of manganese toxicity. Complexation of Mn2+ with 4-amino-2-hydroxybenzoic acid and its N-acetylated metabolite

Joanna Izabela Lachowicz, Valeria Marina Nurchi, Guido Crisponi, Ilaria Cappai, Rosita Cappai, Matteo Busato, Andrea Melchior, Marilena Tolazzi, Massimiliano Peana, Eugenio Garribba, Maria Antonietta Zoroddu, Pierpaolo Coni, Giuseppina Pichiri and Jan Aaseth

New J. Chem., 2018, 42, 8035
DOI: 10.1039/C7NJ04648K

Copper(ii) complexes of macrocyclic and open-chain pseudopeptidic ligands: synthesis, characterization and interaction with dicarboxylates

Enrico Faggi, Raquel Gavara, Michael Bolte, Lluís Fajarí, Luís Juliá, Laura Rodríguez and Ignacio Alfonso

Dalton Trans., 2015, 44, 12700
DOI: 10.1039/C5DT01496D

Zinc(ii) and cadmium(ii) complexes of N-terminally free peptides containing two separate cysteinyl binding sites

Norbert Lihi, Ágnes Grenács, Sarolta Timári, Ildikó Turi, István Bányai, Imre Sóvágó and Katalin Várnagy

New J. Chem., 2015, 39, 8364
DOI: 10.1039/C5NJ01677K

Novel insights into the metal binding ability of ZinT periplasmic protein from Escherichia coli and Salmonella enterica

Denise Bellotti, Magdalena Rowińska-Żyrek and Maurizio Remelli

Dalton Trans., 2020, 49, 9393
DOI: 10.1039/D0DT01626H

Hydroxypyridinones with enhanced iron chelating properties. Synthesis, characterization and in vivo tests of 5-hydroxy-2-(hydroxymethyl)pyridine-4(1H)-one

J. I. Lachowicz, V. M. Nurchi, G. Crisponi, M. G. Jaraquemada-Pelaez, M. Arca, A. Pintus, M. A. Santos, C. Quintanova, L. Gano, Z. Szewczuk, M. A. Zoroddu, M. Peana, A. Domínguez-Martín and D. Choquesillo-Lazarte

Dalton Trans., 2016, 45, 6517
DOI: 10.1039/C6DT00129G

A new tripodal-3-hydroxy-4-pyridinone for iron and aluminium sequestration: synthesis, complexation andin vivostudies

Rosita Cappai, Karam Chand, Joanna I. Lachowicz, Sílvia Chaves, Lurdes Gano, Guido Crisponi, Valeria M. Nurchi, Massimiliano Peana, Maria Antonietta Zoroddu and M. Amélia Santos

New J. Chem., 2018, 42, 8050
DOI: 10.1039/C8NJ00116B

Manganese and cobalt binding in a multi-histidinic fragment

Massimiliano Peana, Serenella Medici, Valeria Marina Nurchi, Guido Crisponi, Joanna Izabela Lachowicz and Maria Antonietta Zoroddu

Dalton Trans., 2013, 42, 16293
DOI: 10.1039/c3dt51091c

Manganism and Parkinson's disease: Mn(ii) and Zn(ii) interaction with a 30-amino acid fragment

Maurizio Remelli, Massimiliano Peana, Serenella Medici, Malgorzata Ostrowska, Elzbieta Gumienna-Kontecka and Maria Antonietta Zoroddu

Dalton Trans., 2016, 45, 5151
DOI: 10.1039/C6DT00184J

Thermodynamic and spectroscopic study of Cu(ii) and Zn(ii) complexes with the (148–156) peptide fragment of C4YJH2, a putative metal transporter ofCandida albicans

Denise Bellotti, Cinzia Tocchio, Remo Guerrini, Magdalena Rowińska-Żyrek and Maurizio Remelli

Metallomics, 2019, 11, 1988
DOI: 10.1039/C9MT00251K

Ni(ii) binding to the 429–460 peptide fragment from human Toll like receptor (hTLR4): a crucial role for nickel-induced contact allergy?

Maria Antonietta Zoroddu, Massimiliano Peana, Serenella Medici, Slawomir Potocki and Henryk Kozlowski

Dalton Trans., 2014, 43, 2764
DOI: 10.1039/C3DT52187G

The Involvement of Amino Acid Side Chains in Shielding the Nickel Coordination Site: An NMR Study

Serenella Medici, Massimiliano Peana, Valeria Nurchi and Maria Zoroddu

Molecules, 2013, 18, 12396
DOI: 10.3390/molecules181012396

Exploring divalent metal ion coordination. Unraveling binding modes in Staphylococcus aureus MntH fragments

Valentyn Dzyhovskyi, Maurizio Remelli and Kamila Stokowa-Sołtys

Journal of Inorganic Biochemistry, 2025, 263, 112769
DOI: 10.1016/j.jinorgbio.2024.112769

"Metal elements and pesticides as risk factors for Parkinson's disease - A review"

Inam Ullah, Longhe Zhao, Yang Hai, Muhammad Fahim, Dhafer Alwayli, Xin Wang and Hongyu Li

Toxicology Reports, 2021, 8, 607
DOI: 10.1016/j.toxrep.2021.03.009

Manganese binding to antioxidant peptides involved in extreme radiation resistance in Deinococcus radiodurans

Massimiliano Peana, Serenella Medici, Heather A. Pangburn, Thomas J. Lamkin, Malgorzata Ostrowska, Elzbieta Gumienna-Kontecka and Maria Antonietta Zoroddu

Journal of Inorganic Biochemistry, 2016, 164, 49
DOI: 10.1016/j.jinorgbio.2016.08.012

Metals and Metal-Nanoparticles in Human Pathologies: From Exposure to Therapy

Joanna Izabela Lachowicz, Luigi Isaia Lecca, Federico Meloni and Marcello Campagna

Molecules, 2021, 26, 6639
DOI: 10.3390/molecules26216639

The Coordination Chemistry of Two Peptidic Models of NFeoB and Core CFeoB Regions of FeoB Protein: Complexes of Fe(II), Mn(II), and Zn(II)

Bartosz Orzel, Malgorzata Ostrowska, Slawomir Potocki, Maria Antonietta Zoroddu, Henryk Kozlowski, Massimiliano Peana and Elzbieta Gumienna-Kontecka

Inorg. Chem., 2025, 64, 5038
DOI: 10.1021/acs.inorgchem.4c05111

A Model for Manganese interaction with Deinococcus radiodurans proteome network involved in ROS response and defense

M. Peana, C.T. Chasapis, G. Simula, S. Medici and M.A. Zoroddu

Journal of Trace Elements in Medicine and Biology, 2018, 50, 465
DOI: 10.1016/j.jtemb.2018.02.001

Development of a Reversible Indicator Displacement Assay Based on the 1-(2-Pyridylazo)-2-naphthol for Colorimetric Determination of Cysteine in Biological Samples and Its Application to Constructing the Paper Test Strips and a Molecular-Scale Set/Reset Memorized Device

Gohar Deilamy-Rad, Khadijeh Asghari and Hossein Tavallali

Appl Biochem Biotechnol, 2020, 192, 85
DOI: 10.1007/s12010-019-03165-0

Ni(II) interaction with a peptide model of the human TLR4 ectodomain

Massimiliano Peana, Karolina Zdyb, Serenella Medici, Alessio Pelucelli, Giancarlo Simula, Elzbieta Gumienna-Kontecka and Maria Antonietta Zoroddu

Journal of Trace Elements in Medicine and Biology, 2017, 44, 151
DOI: 10.1016/j.jtemb.2017.07.006

Decreased circulating Zinc levels in Parkinson’s disease: a meta-analysis study

Ke Du, Ming-Yan Liu, Xin Zhong and Min-Jie Wei

Sci Rep, 2017, 7
DOI: 10.1038/s41598-017-04252-0

Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders

Sarah van Veen, Danny M. SÃ¸rensen, Tine Holemans, Henrik W. Holen, Michael G. Palmgren and Peter Vangheluwe

Front. Mol. Neurosci., 2014, 7
DOI: 10.3389/fnmol.2014.00048

Exploring the Specificity of Rationally Designed Peptides Reconstituted from the Cell-Free Extract of Deinococcus radiodurans toward Mn(II) and Cu(II)

Massimiliano Peana, Elzbieta Gumienna-Kontecka, Francesca Piras, Malgorzata Ostrowska, Karolina Piasta, Karolina Krzywoszynska, Serenella Medici and Maria Antonietta Zoroddu

Inorg. Chem., 2020, 59, 4661
DOI: 10.1021/acs.inorgchem.9b03737

Interaction of Cu(II) and Ni(II) with Ypk9 Protein FragmentviaNMR Studies

Massimiliano Francesco Peana, Serenella Medici, Alessia Ledda, Valeria Marina Nurchi and Maria Antonietta Zoroddu

The Scientific World Journal, 2014, 2014, 1
DOI: 10.1155/2014/656201

Interaction of a chelating agent, 5-hydroxy-2-(hydroxymethyl)pyridin-4(1 H )-one, with Al(III), Cu(II) and Zn(II) ions

Massimiliano Peana, Serenella Medici, Valeria Marina Nurchi, Joanna I. Lachowicz, Guido Crisponi, Eugenio Garribba, Daniele Sanna and Maria Antonietta Zoroddu

Journal of Inorganic Biochemistry, 2017, 171, 18
DOI: 10.1016/j.jinorgbio.2017.03.001

Zinc Interactions with a Soluble Mutated Rat Amylin to Mimic Whole Human Amylin: An Experimental and Simulation Approach to Understand Stoichiometry, Speciation and Coordination of the Metal Complexes

Antonio Magrì, Giovanni Tabbì, Giuseppe Di Natale, Diego La Mendola, Adriana Pietropaolo, Maria Antonietta Zoroddu, Massimiliano Peana and Enrico Rizzarelli

Chemistry A European J, 2020, 26, 13072
DOI: 10.1002/chem.202002114

Speciation in Metal Toxicity and Metal-Based Therapeutics

Douglas Templeton

Toxics, 2015, 3, 170
DOI: 10.3390/toxics3020170

Nanofabrication of Metals and Their Compounds for Effective Medicinal and Environmental Applications (A Review)

Satya, K. Hashmi, S. Gupta, N. Singh, T. Khan and S. Joshi

Russ J Gen Chem, 2023, 93, 635
DOI: 10.1134/S1070363223030209

Positively charged residues play a significant role in enhancing the antibacterial activity of calcitermin

Silvia Leveraro, Maria D'Accolti, Erika Marzola, Elisabetta Caselli, Remo Guerrini, Magdalena Rowinska-Zyrek, Maurizio Remelli and Denise Bellotti

Journal of Inorganic Biochemistry, 2025, 262, 112761
DOI: 10.1016/j.jinorgbio.2024.112761

Nanoparticles released during metal-processing operations: A systematic review

Noemi Paulin, Roberta Pernetti, Enrico Bergamaschi and Enrico Oddone

Cleaner Engineering and Technology, 2025, 24, 100873
DOI: 10.1016/j.clet.2024.100873

A novel dye-based colorimetric chemosensors for sequential detection of Cu2+ and cysteine in aqueous solution

Hossein Tavallali, Gohar Deilamy-Rad, Mohammad Ali Karimi and Eisa Rahimy

Analytical Biochemistry, 2019, 583, 113376
DOI: 10.1016/j.ab.2019.113376