Synthesis and bioevaluation of aryl hydroxamates distinguishing between NAD+ and ATP-dependent DNA ligases

Vandna Kukshal, Mridul Mishra, Arya Ajay, Taran Khanam, Rahul Sharma, Divya Dube, Deepti Chopra, Rama Pati Tripathi and Ravishankar Ramachandran

Med. Chem. Commun., 2012, 3, 453
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Bile acid amphiphiles with tunable head groups as highly selective antitubercular agents

Sandhya Bansal, Manish Singh, Saqib Kidwai, Priyanshu Bhargava, Ashima Singh, Vedagopuram Sreekanth, Ramandeep Singh and Avinash Bajaj

Med. Chem. Commun., 2014, 5, 1761
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Formal Nucleophilic Substitution of Bromocyclopropanes with Azoles

Pavel Ryabchuk, Marina Rubina, Jack Xu and Michael Rubin

Org. Lett., 2012, 14, 1752
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Homology Modeling of NAD + -Dependent DNA Ligase of the Wolbachia Endosymbiont of Brugia malayi and Its Drug Target Potential Using Dispiro-Cycloalkanones

Nidhi Shrivastava, Jeetendra K. Nag, Jyoti Pandey, Rama Pati Tripathi, Priyanka Shah, Mohammad Imran Siddiqi and Shailja Misra-Bhattacharya

Antimicrob Agents Chemother, 2015, 59, 3736
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Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD+-dependent DNA ligase A

Ankita Shukla, Mohammad Afsar, Nelam Kumar, Sanjay Kumar and Ravishankar Ramachandran

Journal of Structural Biology, 2021, 213, 107655
DOI: 10.1016/j.jsb.2020.107655

Biochemical and structural characterization of DNA ligases from bacteria and archaea

Giulia Pergolizzi, Gerd K. Wagner and Richard P. Bowater

Bioscience Reports, 2016, 36
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Formal Substitution of Bromocyclopropanes with Nitrogen Nucleophiles

Joseph E. Banning, Jacob Gentillon, Pavel G. Ryabchuk, Anthony R. Prosser, Andrew Rogers, Andrew Edwards, Andrew Holtzen, Ivan A. Babkov, Marina Rubina and Michael Rubin

J. Org. Chem., 2013, 78, 7601
DOI: 10.1021/jo4011798

Identification through structure-based methods of a bacterial NAD+-dependent DNA ligase inhibitor that avoids known resistance mutations

Kerry Murphy-Benenato, Hongming Wang, Helen M. McGuire, Hajnalka E. Davis, Ning Gao, D. Bryan Prince, Haris Jahic, Suzanne S. Stokes and P. Ann Boriack-Sjodin

Bioorganic & Medicinal Chemistry Letters, 2014, 24, 360
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